GET https://kbin.spritesserver.nl/u/@Chetzemoka@startrek.website/hot/2023-12-23::2023-12-23

Security

Token

There is no security token.

Firewall

main Name
Security enabled
Stateless

Configuration

Key Value
provider security.user.provider.concrete.app_user_provider
context main
entry_point App\Security\KbinAuthenticator
user_checker App\Security\UserChecker
access_denied_handler (none)
access_denied_url (none)
authenticators
[
  "two_factor"
  "remember_me"
  "App\Security\KbinAuthenticator"
  "App\Security\FacebookAuthenticator"
  "App\Security\GoogleAuthenticator"
  "App\Security\GithubAuthenticator"
  "App\Security\KeycloakAuthenticator"
]

Listeners

Listener Duration Response
Symfony\Component\Security\Http\Firewall\ChannelListener {#723
  -map: Symfony\Component\Security\Http\AccessMap {#722 …}
  -logger: Monolog\Logger {#783 …}
  -httpPort: 80
  -httpsPort: 443
}
0.00 ms (none)
Symfony\Component\Security\Http\Firewall\ContextListener {#706
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\TokenStorage {#1017 …}
  -sessionKey: "_security_main"
  -logger: Monolog\Logger {#783 …}
  -userProviders: Symfony\Component\DependencyInjection\Argument\RewindableGenerator {#705 …}
  -dispatcher: Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher {#747 …}
  -registered: false
  -trustResolver: Scheb\TwoFactorBundle\Security\Authentication\AuthenticationTrustResolver {#780 …}
  -sessionTrackerEnabler: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage::enableUsageTracking(): void {#703 …}
}
0.13 ms (none)
Symfony\Component\Security\Http\Firewall\AuthenticatorManagerListener {#584
  -authenticatorManager: Symfony\Component\Security\Http\Authentication\AuthenticatorManager {#595 …}
}
0.00 ms (none)
Scheb\TwoFactorBundle\Security\Http\Firewall\TwoFactorAccessListener {#582
  -twoFactorFirewallConfig: Scheb\TwoFactorBundle\Security\TwoFactor\TwoFactorFirewallConfig {#842 …}
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -twoFactorAccessDecider: Scheb\TwoFactorBundle\Security\Authorization\TwoFactorAccessDecider {#581 …}
}
0.03 ms (none)
Symfony\Component\Security\Http\Firewall\AccessListener {#579
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -accessDecisionManager: Symfony\Component\Security\Core\Authorization\TraceableAccessDecisionManager {#937 …}
  -map: Symfony\Component\Security\Http\AccessMap {#722 …}
}
0.00 ms (none)
Symfony\Component\Security\Http\Firewall\LogoutListener {#786
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -options: [
    "csrf_parameter" => "_csrf_token"
    "csrf_token_id" => "logout"
    "logout_path" => "app_logout"
  ]
  -httpUtils: Symfony\Component\Security\Http\HttpUtils {#841 …}
  -csrfTokenManager: Symfony\Component\Security\Csrf\CsrfTokenManager {#1015 …}
  -eventDispatcher: Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher {#747 …}
}
0.00 ms (none)

Authenticators

No authenticators have been recorded. Check previous profiles on your authentication endpoint.

Access Decision

affirmative Strategy
# Voter class
1
"Symfony\Component\Security\Core\Authorization\Voter\AuthenticatedVoter"
2
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
3
"Symfony\Component\Security\Core\Authorization\Voter\RoleHierarchyVoter"
4
"Symfony\Component\Security\Core\Authorization\Voter\ExpressionVoter"
5
"App\Security\Voter\EntryCommentVoter"
6
"App\Security\Voter\EntryVoter"
7
"App\Security\Voter\MagazineVoter"
8
"App\Security\Voter\MessageThreadVoter"
9
"App\Security\Voter\MessageVoter"
10
"App\Security\Voter\NotificationVoter"
11
"App\Security\Voter\OAuth2UserConsentVoter"
12
"App\Security\Voter\PostCommentVoter"
13
"App\Security\Voter\PostVoter"
14
"App\Security\Voter\UserVoter"

Access decision log

# Result Attributes Object
1 DENIED ROLE_USER
null
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"Symfony\Component\Security\Core\Authorization\Voter\RoleHierarchyVoter"
ACCESS DENIED
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS ABSTAIN
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
2 DENIED moderate
Proxies\__CG__\App\Entity\Entry {#1571
  +user: Proxies\__CG__\App\Entity\User {#1740 …}
  +magazine: Proxies\__CG__\App\Entity\Magazine {#1572 …}
  +image: null
  +domain: Proxies\__CG__\App\Entity\Domain {#1407 …}
  +slug: "What-is-Something-Scientific-that-you-just-don-t-believe-in"
  +title: "What is Something Scientific that you just don't believe in at all?"
  +url: null
  +body: "EDIT: Let’s cool it with the downvotes, dudes. We’re not out to cut funding to your black hole detection chamber or revoke the degrees of chiropractors just because a couple of us don’t believe in it, okay? Chill out, participate with the prompt and continue with having a nice day. I’m sure almost everybody has something to add."
  +type: "article"
  +lang: "en"
  +isOc: false
  +hasEmbed: false
  +commentCount: 442
  +favouriteCount: 259
  +score: 0
  +isAdult: false
  +sticky: false
  +lastActive: DateTime @1703801499 {#2462
    date: 2023-12-28 23:11:39.0 +01:00
  }
  +ip: null
  +adaAmount: 0
  +tags: null
  +mentions: null
  +comments: Doctrine\ORM\PersistentCollection {#1883 …}
  +votes: Doctrine\ORM\PersistentCollection {#1705 …}
  +reports: Doctrine\ORM\PersistentCollection {#1723 …}
  +favourites: Doctrine\ORM\PersistentCollection {#1404 …}
  +notifications: Doctrine\ORM\PersistentCollection {#1405 …}
  +badges: Doctrine\ORM\PersistentCollection {#2025 …}
  +children: [
    1 => App\Entity\EntryComment {#1620
      +user: App\Entity\User {#265 …}
      +entry: Proxies\__CG__\App\Entity\Entry {#1571 …2}
      +magazine: Proxies\__CG__\App\Entity\Magazine {#1572 …}
      +image: null
      +parent: Proxies\__CG__\App\Entity\EntryComment {#1613 …}
      +root: Proxies\__CG__\App\Entity\EntryComment {#1613 …}
      +body: """
        But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
        \n
        Same as it ever was.
        """
      +lang: "en"
      +isAdult: false
      +favouriteCount: 5
      +score: 0
      +lastActive: DateTime @1703366725 {#1555
        date: 2023-12-23 22:25:25.0 +01:00
      }
      +ip: null
      +tags: null
      +mentions: [
        "@doctorcrimson@lemmy.world"
        "@captain_aggravated@sh.itjust.works"
      ]
      +children: Doctrine\ORM\PersistentCollection {#1604 …}
      +nested: Doctrine\ORM\PersistentCollection {#1619 …}
      +votes: Doctrine\ORM\PersistentCollection {#1701 …}
      +reports: Doctrine\ORM\PersistentCollection {#1687 …}
      +favourites: Doctrine\ORM\PersistentCollection {#1689 …}
      +notifications: Doctrine\ORM\PersistentCollection {#1691 …}
      -id: 246935
      -bodyTs: "'acknowledg':8,78 'add':69 'allow':91 'astronom':41 'astronomi':13 'caus':32 'contribut':85 'current':25,38 'dark':23 'effect':34,48 'ever':101 'exact':54 'fail':76 'field':14 'figur':57,95 'final':94 'foundat':88 'fulli':7 'hey':55 'hoard':80 'hope':50 'liter':4 'll':65 'name':22,71 'pantheon':74 'paper':62 'peopl':83 'person':68 'physic':11 'physicist':39 'prais':66 'publish':52 'receiv':20 'research':46,89 'see':29 'spend':43 'thing':19 'time':45 'true':5"
      +ranking: 0
      +commentCount: 0
      +upVotes: 0
      +downVotes: 0
      +visibility: "visible             "
      +apId: "https://startrek.website/comment/5183633"
      +editedAt: null
      +createdAt: DateTimeImmutable @1703366725 {#1621
        date: 2023-12-23 22:25:25.0 +01:00
      }
      +"title": 246935
    }
    2 => App\Entity\EntryComment {#1696
      +user: App\Entity\User {#265 …}
      +entry: Proxies\__CG__\App\Entity\Entry {#1571 …2}
      +magazine: Proxies\__CG__\App\Entity\Magazine {#1572 …}
      +image: null
      +parent: Proxies\__CG__\App\Entity\EntryComment {#1650 …}
      +root: Proxies\__CG__\App\Entity\EntryComment {#1650 …}
      +body: "That’s not science."
      +lang: "en"
      +isAdult: false
      +favouriteCount: 6
      +score: 0
      +lastActive: DateTime @1703365714 {#1428
        date: 2023-12-23 22:08:34.0 +01:00
      }
      +ip: null
      +tags: null
      +mentions: [
        "@doctorcrimson@lemmy.world"
        "@AzureInfinity@leminal.space"
      ]
      +children: Doctrine\ORM\PersistentCollection {#1679 …}
      +nested: Doctrine\ORM\PersistentCollection {#1667 …}
      +votes: Doctrine\ORM\PersistentCollection {#1670 …}
      +reports: Doctrine\ORM\PersistentCollection {#1678 …}
      +favourites: Doctrine\ORM\PersistentCollection {#1573 …}
      +notifications: Doctrine\ORM\PersistentCollection {#1586 …}
      -id: 246902
      -bodyTs: "'scienc':4"
      +ranking: 0
      +commentCount: 0
      +upVotes: 0
      +downVotes: 0
      +visibility: "visible             "
      +apId: "https://startrek.website/comment/5183408"
      +editedAt: null
      +createdAt: DateTimeImmutable @1703365714 {#1440
        date: 2023-12-23 22:08:34.0 +01:00
      }
      +"title": 246902
    }
    0 => App\Entity\EntryComment {#1550
      +user: App\Entity\User {#265 …}
      +entry: Proxies\__CG__\App\Entity\Entry {#1571 …2}
      +magazine: Proxies\__CG__\App\Entity\Magazine {#1572 …}
      +image: null
      +parent: Proxies\__CG__\App\Entity\EntryComment {#1525 …}
      +root: Proxies\__CG__\App\Entity\EntryComment {#1528 …}
      +body: """
        Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
        \n
        For example, it is well established that there is a subset of people with Crohn’s disease who go into remission while taking an antidepressant called bupropion and we have no idea why. No one believes this is because these people’s Crohn’s was caused by a psychological problem, but rather that the bupropion appears to have effects on the immune system that aren’t well understood. And this appears to only work in certain people. Do those people have a different “kind” of Crohn’s? Different underlying genetic response to bupropion? Those questions aren’t as easy to answer as you might think.\n
        \n
        [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
        """
      +lang: "en"
      +isAdult: false
      +favouriteCount: 2
      +score: 0
      +lastActive: DateTime @1703366310 {#1577
        date: 2023-12-23 22:18:30.0 +01:00
      }
      +ip: null
      +tags: null
      +mentions: [
        "@doctorcrimson@lemmy.world"
        "@Sekrayray@lemmy.world"
        "@russjr08@bitforged.space"
      ]
      +children: Doctrine\ORM\PersistentCollection {#1527 …}
      +nested: Doctrine\ORM\PersistentCollection {#1548 …}
      +votes: Doctrine\ORM\PersistentCollection {#1566 …}
      +reports: Doctrine\ORM\PersistentCollection {#1562 …}
      +favourites: Doctrine\ORM\PersistentCollection {#1554 …}
      +notifications: Doctrine\ORM\PersistentCollection {#1556 …}
      -id: 246926
      -bodyTs: "'/article/':152 '/article/s0016-5085(03)01316-7/fulltext#:~:text=another%202%20patients%20with%20crohn''s,factor%2d%ce%b1%20(tnf)).':157 '/fulltext':153 '/pmc/articles/pmc1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc1774386/)':44 'also':31 'answer':145 'antidepress':69 'appear':100,115 'aren':109,140 'awar':41 'believ':80 'bupropion':71,99,137 'call':70 'caus':90 'certain':120 'comment':26 'complic':35 'crohn':2,14,29,59,87,130 'differ':5,13,18,127,132 'diseas':61 'easi':143 'effect':103 'establish':50 'even':1 'exampl':46 'explain':11 'general':38 'genet':134 'go':63 'idea':76 'immun':106 'kind':128 'like':24 'lupus':28 'might':148 'much':23,33 'one':79 'patient':16 'peopl':57,85,121,124 'problem':94 'psycholog':93 'public':39 'question':139 'rather':96 'remiss':65 'respond':17 'respons':135 'subset':55 'subtyp':6 'suspect':9 'system':107 'take':67 'text':154 'think':149 'treatment':22 'under':133 'understood':112 'well':49,111 'work':118 'www.gastrojournal.org':151,156 'www.gastrojournal.org/article/':150 'www.gastrojournal.org/article/s0016-5085(03)01316-7/fulltext#:~:text=another%202%20patients%20with%20crohn''s,factor%2d%ce%b1%20(tnf)).':155 'www.ncbi.nlm.nih.gov':43 'www.ncbi.nlm.nih.gov/pmc/articles/pmc1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc1774386/)':42"
      +ranking: 0
      +commentCount: 0
      +upVotes: 0
      +downVotes: 0
      +visibility: "visible             "
      +apId: "https://startrek.website/comment/5183558"
      +editedAt: null
      +createdAt: DateTimeImmutable @1703366310 {#1567
        date: 2023-12-23 22:18:30.0 +01:00
      }
      +"title": 246926
    }
  ]
  -id: 23947
  -titleTs: "'believ':10 'scientif':4 'someth':3"
  -bodyTs: "'add':62 'almost':57 'believ':37 'black':19 'chamber':22 'chill':41 'chiropractor':28 'continu':48 'cool':4 'coupl':32 'cut':15 'day':53 'degre':26 'detect':21 'downvot':8 'dude':9 'edit':1 'everybodi':58 'fund':16 'hole':20 'let':2 'm':55 'nice':52 'okay':40 'particip':43 'prompt':46 're':11 'revok':24 'someth':60 'sure':56 'us':34"
  +cross: false
  +upVotes: 0
  +downVotes: 0
  +ranking: 1703300170
  +visibility: "visible             "
  +apId: "https://lemmy.world/post/9845370"
  +editedAt: null
  +createdAt: DateTimeImmutable @1703213770 {#1698
    date: 2023-12-22 03:56:10.0 +01:00
  }
  +__isInitialized__: true
   …2
}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS DENIED
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
3 DENIED edit
Proxies\__CG__\App\Entity\Entry {#1571
  +user: Proxies\__CG__\App\Entity\User {#1740 …}
  +magazine: Proxies\__CG__\App\Entity\Magazine {#1572 …}
  +image: null
  +domain: Proxies\__CG__\App\Entity\Domain {#1407 …}
  +slug: "What-is-Something-Scientific-that-you-just-don-t-believe-in"
  +title: "What is Something Scientific that you just don't believe in at all?"
  +url: null
  +body: "EDIT: Let’s cool it with the downvotes, dudes. We’re not out to cut funding to your black hole detection chamber or revoke the degrees of chiropractors just because a couple of us don’t believe in it, okay? Chill out, participate with the prompt and continue with having a nice day. I’m sure almost everybody has something to add."
  +type: "article"
  +lang: "en"
  +isOc: false
  +hasEmbed: false
  +commentCount: 442
  +favouriteCount: 259
  +score: 0
  +isAdult: false
  +sticky: false
  +lastActive: DateTime @1703801499 {#2462
    date: 2023-12-28 23:11:39.0 +01:00
  }
  +ip: null
  +adaAmount: 0
  +tags: null
  +mentions: null
  +comments: Doctrine\ORM\PersistentCollection {#1883 …}
  +votes: Doctrine\ORM\PersistentCollection {#1705 …}
  +reports: Doctrine\ORM\PersistentCollection {#1723 …}
  +favourites: Doctrine\ORM\PersistentCollection {#1404 …}
  +notifications: Doctrine\ORM\PersistentCollection {#1405 …}
  +badges: Doctrine\ORM\PersistentCollection {#2025 …}
  +children: [
    1 => App\Entity\EntryComment {#1620
      +user: App\Entity\User {#265 …}
      +entry: Proxies\__CG__\App\Entity\Entry {#1571 …2}
      +magazine: Proxies\__CG__\App\Entity\Magazine {#1572 …}
      +image: null
      +parent: Proxies\__CG__\App\Entity\EntryComment {#1613 …}
      +root: Proxies\__CG__\App\Entity\EntryComment {#1613 …}
      +body: """
        But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
        \n
        Same as it ever was.
        """
      +lang: "en"
      +isAdult: false
      +favouriteCount: 5
      +score: 0
      +lastActive: DateTime @1703366725 {#1555
        date: 2023-12-23 22:25:25.0 +01:00
      }
      +ip: null
      +tags: null
      +mentions: [
        "@doctorcrimson@lemmy.world"
        "@captain_aggravated@sh.itjust.works"
      ]
      +children: Doctrine\ORM\PersistentCollection {#1604 …}
      +nested: Doctrine\ORM\PersistentCollection {#1619 …}
      +votes: Doctrine\ORM\PersistentCollection {#1701 …}
      +reports: Doctrine\ORM\PersistentCollection {#1687 …}
      +favourites: Doctrine\ORM\PersistentCollection {#1689 …}
      +notifications: Doctrine\ORM\PersistentCollection {#1691 …}
      -id: 246935
      -bodyTs: "'acknowledg':8,78 'add':69 'allow':91 'astronom':41 'astronomi':13 'caus':32 'contribut':85 'current':25,38 'dark':23 'effect':34,48 'ever':101 'exact':54 'fail':76 'field':14 'figur':57,95 'final':94 'foundat':88 'fulli':7 'hey':55 'hoard':80 'hope':50 'liter':4 'll':65 'name':22,71 'pantheon':74 'paper':62 'peopl':83 'person':68 'physic':11 'physicist':39 'prais':66 'publish':52 'receiv':20 'research':46,89 'see':29 'spend':43 'thing':19 'time':45 'true':5"
      +ranking: 0
      +commentCount: 0
      +upVotes: 0
      +downVotes: 0
      +visibility: "visible             "
      +apId: "https://startrek.website/comment/5183633"
      +editedAt: null
      +createdAt: DateTimeImmutable @1703366725 {#1621
        date: 2023-12-23 22:25:25.0 +01:00
      }
      +"title": 246935
    }
    2 => App\Entity\EntryComment {#1696
      +user: App\Entity\User {#265 …}
      +entry: Proxies\__CG__\App\Entity\Entry {#1571 …2}
      +magazine: Proxies\__CG__\App\Entity\Magazine {#1572 …}
      +image: null
      +parent: Proxies\__CG__\App\Entity\EntryComment {#1650 …}
      +root: Proxies\__CG__\App\Entity\EntryComment {#1650 …}
      +body: "That’s not science."
      +lang: "en"
      +isAdult: false
      +favouriteCount: 6
      +score: 0
      +lastActive: DateTime @1703365714 {#1428
        date: 2023-12-23 22:08:34.0 +01:00
      }
      +ip: null
      +tags: null
      +mentions: [
        "@doctorcrimson@lemmy.world"
        "@AzureInfinity@leminal.space"
      ]
      +children: Doctrine\ORM\PersistentCollection {#1679 …}
      +nested: Doctrine\ORM\PersistentCollection {#1667 …}
      +votes: Doctrine\ORM\PersistentCollection {#1670 …}
      +reports: Doctrine\ORM\PersistentCollection {#1678 …}
      +favourites: Doctrine\ORM\PersistentCollection {#1573 …}
      +notifications: Doctrine\ORM\PersistentCollection {#1586 …}
      -id: 246902
      -bodyTs: "'scienc':4"
      +ranking: 0
      +commentCount: 0
      +upVotes: 0
      +downVotes: 0
      +visibility: "visible             "
      +apId: "https://startrek.website/comment/5183408"
      +editedAt: null
      +createdAt: DateTimeImmutable @1703365714 {#1440
        date: 2023-12-23 22:08:34.0 +01:00
      }
      +"title": 246902
    }
    0 => App\Entity\EntryComment {#1550
      +user: App\Entity\User {#265 …}
      +entry: Proxies\__CG__\App\Entity\Entry {#1571 …2}
      +magazine: Proxies\__CG__\App\Entity\Magazine {#1572 …}
      +image: null
      +parent: Proxies\__CG__\App\Entity\EntryComment {#1525 …}
      +root: Proxies\__CG__\App\Entity\EntryComment {#1528 …}
      +body: """
        Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
        \n
        For example, it is well established that there is a subset of people with Crohn’s disease who go into remission while taking an antidepressant called bupropion and we have no idea why. No one believes this is because these people’s Crohn’s was caused by a psychological problem, but rather that the bupropion appears to have effects on the immune system that aren’t well understood. And this appears to only work in certain people. Do those people have a different “kind” of Crohn’s? Different underlying genetic response to bupropion? Those questions aren’t as easy to answer as you might think.\n
        \n
        [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
        """
      +lang: "en"
      +isAdult: false
      +favouriteCount: 2
      +score: 0
      +lastActive: DateTime @1703366310 {#1577
        date: 2023-12-23 22:18:30.0 +01:00
      }
      +ip: null
      +tags: null
      +mentions: [
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4 DENIED moderate
Proxies\__CG__\App\Entity\Entry {#1571
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  +slug: "What-is-Something-Scientific-that-you-just-don-t-believe-in"
  +title: "What is Something Scientific that you just don't believe in at all?"
  +url: null
  +body: "EDIT: Let’s cool it with the downvotes, dudes. We’re not out to cut funding to your black hole detection chamber or revoke the degrees of chiropractors just because a couple of us don’t believe in it, okay? Chill out, participate with the prompt and continue with having a nice day. I’m sure almost everybody has something to add."
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        But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
        \n
        Same as it ever was.
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        Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
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        [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
        """
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6 DENIED moderate
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    +slug: "What-is-Something-Scientific-that-you-just-don-t-believe-in"
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          Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
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          [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
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          \n
          [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
          """
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    But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
    \n
    Same as it ever was.
    """
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          Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
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          For example, it is well established that there is a subset of people with Crohn’s disease who go into remission while taking an antidepressant called bupropion and we have no idea why. No one believes this is because these people’s Crohn’s was caused by a psychological problem, but rather that the bupropion appears to have effects on the immune system that aren’t well understood. And this appears to only work in certain people. Do those people have a different “kind” of Crohn’s? Different underlying genetic response to bupropion? Those questions aren’t as easy to answer as you might think.\n
          \n
          [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
          """
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    But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
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    Same as it ever was.
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          Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
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          \n
          [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
          """
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    But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
    \n
    Same as it ever was.
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          But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
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          Same as it ever was.
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          date: 2023-12-23 22:25:25.0 +01:00
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      2 => App\Entity\EntryComment {#1696}
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          Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
          \n
          For example, it is well established that there is a subset of people with Crohn’s disease who go into remission while taking an antidepressant called bupropion and we have no idea why. No one believes this is because these people’s Crohn’s was caused by a psychological problem, but rather that the bupropion appears to have effects on the immune system that aren’t well understood. And this appears to only work in certain people. Do those people have a different “kind” of Crohn’s? Different underlying genetic response to bupropion? Those questions aren’t as easy to answer as you might think.\n
          \n
          [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
          """
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11 DENIED edit
App\Entity\EntryComment {#1696
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    +url: null
    +body: "EDIT: Let’s cool it with the downvotes, dudes. We’re not out to cut funding to your black hole detection chamber or revoke the degrees of chiropractors just because a couple of us don’t believe in it, okay? Chill out, participate with the prompt and continue with having a nice day. I’m sure almost everybody has something to add."
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          But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
          \n
          Same as it ever was.
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          Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
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          \n
          [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
          """
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          "@Sekrayray@lemmy.world"
          "@russjr08@bitforged.space"
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12 DENIED moderate
App\Entity\EntryComment {#1696
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    +slug: "What-is-Something-Scientific-that-you-just-don-t-believe-in"
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    +url: null
    +body: "EDIT: Let’s cool it with the downvotes, dudes. We’re not out to cut funding to your black hole detection chamber or revoke the degrees of chiropractors just because a couple of us don’t believe in it, okay? Chill out, participate with the prompt and continue with having a nice day. I’m sure almost everybody has something to add."
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          But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
          \n
          Same as it ever was.
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          "@captain_aggravated@sh.itjust.works"
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          Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
          \n
          For example, it is well established that there is a subset of people with Crohn’s disease who go into remission while taking an antidepressant called bupropion and we have no idea why. No one believes this is because these people’s Crohn’s was caused by a psychological problem, but rather that the bupropion appears to have effects on the immune system that aren’t well understood. And this appears to only work in certain people. Do those people have a different “kind” of Crohn’s? Different underlying genetic response to bupropion? Those questions aren’t as easy to answer as you might think.\n
          \n
          [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
          """
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14 DENIED moderate
App\Entity\EntryComment {#1550
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          But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
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          Same as it ever was.
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    Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
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    For example, it is well established that there is a subset of people with Crohn’s disease who go into remission while taking an antidepressant called bupropion and we have no idea why. No one believes this is because these people’s Crohn’s was caused by a psychological problem, but rather that the bupropion appears to have effects on the immune system that aren’t well understood. And this appears to only work in certain people. Do those people have a different “kind” of Crohn’s? Different underlying genetic response to bupropion? Those questions aren’t as easy to answer as you might think.\n
    \n
    [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
    """
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15 DENIED edit
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          But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
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    Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
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    \n
    [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
    """
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16 DENIED moderate
App\Entity\EntryComment {#1550
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          But that’s literally true and fully acknowledged by the physics and astronomy fields. It’s why those things received the names “dark.” Because currently we can’t see what’s causing those effects. And there are currently physicists and astronomers who spend their time researching these effects in hopes of publishing that exact “Hey! I figured out what it is” paper. Then we’ll praise that person, add their name to the pantheon and fail to acknowledge the hoards of other people who contributed to the foundational research that allowed them to finally figure it out.\n
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  +body: """
    Even Crohn’s has different subtypes that are suspected to explain why different Crohn’s patients respond differently to the same treatments. Much like the comment about lupus. Crohn’s also is much more complicated than the general public is aware.\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774386/)\n
    \n
    For example, it is well established that there is a subset of people with Crohn’s disease who go into remission while taking an antidepressant called bupropion and we have no idea why. No one believes this is because these people’s Crohn’s was caused by a psychological problem, but rather that the bupropion appears to have effects on the immune system that aren’t well understood. And this appears to only work in certain people. Do those people have a different “kind” of Crohn’s? Different underlying genetic response to bupropion? Those questions aren’t as easy to answer as you might think.\n
    \n
    [www.gastrojournal.org/article/…/fulltext#:~:text=…](https://www.gastrojournal.org/article/S0016-5085(03)01316-7/fulltext#:~:text=Another%202%20patients%20with%20Crohn's,factor%2D%CE%B1%20(TNF)).
    """
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    "@Sekrayray@lemmy.world"
    "@russjr08@bitforged.space"
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  -id: 246926
  -bodyTs: "'/article/':152 '/article/s0016-5085(03)01316-7/fulltext#:~:text=another%202%20patients%20with%20crohn''s,factor%2d%ce%b1%20(tnf)).':157 '/fulltext':153 '/pmc/articles/pmc1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc1774386/)':44 'also':31 'answer':145 'antidepress':69 'appear':100,115 'aren':109,140 'awar':41 'believ':80 'bupropion':71,99,137 'call':70 'caus':90 'certain':120 'comment':26 'complic':35 'crohn':2,14,29,59,87,130 'differ':5,13,18,127,132 'diseas':61 'easi':143 'effect':103 'establish':50 'even':1 'exampl':46 'explain':11 'general':38 'genet':134 'go':63 'idea':76 'immun':106 'kind':128 'like':24 'lupus':28 'might':148 'much':23,33 'one':79 'patient':16 'peopl':57,85,121,124 'problem':94 'psycholog':93 'public':39 'question':139 'rather':96 'remiss':65 'respond':17 'respons':135 'subset':55 'subtyp':6 'suspect':9 'system':107 'take':67 'text':154 'think':149 'treatment':22 'under':133 'understood':112 'well':49,111 'work':118 'www.gastrojournal.org':151,156 'www.gastrojournal.org/article/':150 'www.gastrojournal.org/article/s0016-5085(03)01316-7/fulltext#:~:text=another%202%20patients%20with%20crohn''s,factor%2d%ce%b1%20(tnf)).':155 'www.ncbi.nlm.nih.gov':43 'www.ncbi.nlm.nih.gov/pmc/articles/pmc1774386/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc1774386/)':42"
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