Security

Token

There is no security token.

Firewall

main Name
Security enabled
Stateless

Configuration

Key Value
provider security.user.provider.concrete.app_user_provider
context main
entry_point App\Security\KbinAuthenticator
user_checker App\Security\UserChecker
access_denied_handler (none)
access_denied_url (none)
authenticators
[
  "two_factor"
  "remember_me"
  "App\Security\KbinAuthenticator"
  "App\Security\FacebookAuthenticator"
  "App\Security\GoogleAuthenticator"
  "App\Security\GithubAuthenticator"
  "App\Security\KeycloakAuthenticator"
]

Listeners

Listener Duration Response
Symfony\Component\Security\Http\Firewall\ChannelListener {#723
  -map: Symfony\Component\Security\Http\AccessMap {#722 …}
  -logger: Monolog\Logger {#783 …}
  -httpPort: 80
  -httpsPort: 443
}
0.00 ms (none)
Symfony\Component\Security\Http\Firewall\ContextListener {#706
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\TokenStorage {#1017 …}
  -sessionKey: "_security_main"
  -logger: Monolog\Logger {#783 …}
  -userProviders: Symfony\Component\DependencyInjection\Argument\RewindableGenerator {#705 …}
  -dispatcher: Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher {#747 …}
  -registered: false
  -trustResolver: Scheb\TwoFactorBundle\Security\Authentication\AuthenticationTrustResolver {#780 …}
  -sessionTrackerEnabler: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage::enableUsageTracking(): void {#703 …}
}
5.13 ms (none)
Symfony\Component\Security\Http\Firewall\AuthenticatorManagerListener {#584
  -authenticatorManager: Symfony\Component\Security\Http\Authentication\AuthenticatorManager {#595 …}
}
0.00 ms (none)
Scheb\TwoFactorBundle\Security\Http\Firewall\TwoFactorAccessListener {#582
  -twoFactorFirewallConfig: Scheb\TwoFactorBundle\Security\TwoFactor\TwoFactorFirewallConfig {#842 …}
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -twoFactorAccessDecider: Scheb\TwoFactorBundle\Security\Authorization\TwoFactorAccessDecider {#581 …}
}
0.05 ms (none)
Symfony\Component\Security\Http\Firewall\AccessListener {#579
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -accessDecisionManager: Symfony\Component\Security\Core\Authorization\TraceableAccessDecisionManager {#937 …}
  -map: Symfony\Component\Security\Http\AccessMap {#722 …}
}
0.00 ms (none)
Symfony\Component\Security\Http\Firewall\LogoutListener {#786
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -options: [
    "csrf_parameter" => "_csrf_token"
    "csrf_token_id" => "logout"
    "logout_path" => "app_logout"
  ]
  -httpUtils: Symfony\Component\Security\Http\HttpUtils {#841 …}
  -csrfTokenManager: Symfony\Component\Security\Csrf\CsrfTokenManager {#1015 …}
  -eventDispatcher: Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher {#747 …}
}
0.00 ms (none)

Authenticators

No authenticators have been recorded. Check previous profiles on your authentication endpoint.

Access Decision

affirmative Strategy
# Voter class
1
"Symfony\Component\Security\Core\Authorization\Voter\AuthenticatedVoter"
2
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
3
"Symfony\Component\Security\Core\Authorization\Voter\RoleHierarchyVoter"
4
"Symfony\Component\Security\Core\Authorization\Voter\ExpressionVoter"
5
"App\Security\Voter\EntryCommentVoter"
6
"App\Security\Voter\EntryVoter"
7
"App\Security\Voter\MagazineVoter"
8
"App\Security\Voter\MessageThreadVoter"
9
"App\Security\Voter\MessageVoter"
10
"App\Security\Voter\NotificationVoter"
11
"App\Security\Voter\OAuth2UserConsentVoter"
12
"App\Security\Voter\PostCommentVoter"
13
"App\Security\Voter\PostVoter"
14
"App\Security\Voter\UserVoter"

Access decision log

# Result Attributes Object
1 DENIED ROLE_USER
null
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"Symfony\Component\Security\Core\Authorization\Voter\RoleHierarchyVoter"
ACCESS DENIED
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS ABSTAIN
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
2 DENIED moderate
App\Entity\Entry {#2388
  +user: Proxies\__CG__\App\Entity\User {#1943 …}
  +magazine: App\Entity\Magazine {#266
    +icon: Proxies\__CG__\App\Entity\Image {#247 …}
    +name: "upliftingnews@lemmy.world"
    +title: "upliftingnews"
    +description: """
      **Welcome to /c/UpliftingNews**, a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity often found in today’s news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news that gives hope, fosters empathy, and strengthens the belief in humanity’s capacity for good.\n
      \n
      Here in /c/UpliftingNews, we uphold the values of respect, empathy, and inclusivity, fostering a supportive and vibrant community. We encourage you to share your positive news, comment, engage in uplifting conversations, and find solace in the goodness that exists around us. We are more than a news-sharing platform; we are a community built on the power of positivity and the collective desire for a more hopeful world. Remember, your small acts of kindness can be someone else’s big ray of hope. Be part of the positivity revolution; share, uplift, inspire!
      """
    +rules: null
    +subscriptionsCount: 1
    +entryCount: 479
    +entryCommentCount: 3989
    +postCount: 1
    +postCommentCount: 1
    +isAdult: false
    +customCss: null
    +lastActive: DateTime @1729387639 {#276
      date: 2024-10-20 03:27:19.0 +02:00
    }
    +markedForDeletionAt: null
    +tags: null
    +moderators: Doctrine\ORM\PersistentCollection {#238 …}
    +ownershipRequests: Doctrine\ORM\PersistentCollection {#234 …}
    +moderatorRequests: Doctrine\ORM\PersistentCollection {#223 …}
    +entries: Doctrine\ORM\PersistentCollection {#181 …}
    +posts: Doctrine\ORM\PersistentCollection {#139 …}
    +subscriptions: Doctrine\ORM\PersistentCollection {#201 …}
    +bans: Doctrine\ORM\PersistentCollection {#118 …}
    +reports: Doctrine\ORM\PersistentCollection {#104 …}
    +badges: Doctrine\ORM\PersistentCollection {#82 …}
    +logs: Doctrine\ORM\PersistentCollection {#72 …}
    +awards: Doctrine\ORM\PersistentCollection {#61 …}
    +categories: Doctrine\ORM\PersistentCollection {#1820 …}
    -id: 16
    +apId: "upliftingnews@lemmy.world"
    +apProfileId: "https://lemmy.world/c/upliftingnews"
    +apPublicUrl: "https://lemmy.world/c/upliftingnews"
    +apFollowersUrl: "https://lemmy.world/c/upliftingnews/followers"
    +apInboxUrl: "https://lemmy.world/inbox"
    +apDomain: "lemmy.world"
    +apPreferredUsername: "upliftingnews"
    +apDiscoverable: true
    +apManuallyApprovesFollowers: null
    +privateKey: null
    +publicKey: null
    +apFetchedAt: DateTime @1729583670 {#270
      date: 2024-10-22 09:54:30.0 +02:00
    }
    +apDeletedAt: null
    +apTimeoutAt: null
    +visibility: "visible             "
    +createdAt: DateTimeImmutable @1687397496 {#272
      date: 2023-06-22 03:31:36.0 +02:00
    }
  }
  +image: Proxies\__CG__\App\Entity\Image {#1962 …}
  +domain: Proxies\__CG__\App\Entity\Domain {#1924 …}
  +slug: "Tumor-destroying-sound-waves-receive-FDA-approval-for-liver-treatment-in"
  +title: "Tumor-destroying sound waves receive FDA approval for liver treatment in humans"
  +url: "https://news.umich.edu/tumor-destroying-sound-waves-receive-fda-approval-for-liver-treatment-in-humans/"
  +body: null
  +type: "link"
  +lang: "en"
  +isOc: false
  +hasEmbed: false
  +commentCount: 16
  +favouriteCount: 379
  +score: 0
  +isAdult: false
  +sticky: false
  +lastActive: DateTime @1697403497 {#2410
    date: 2023-10-15 22:58:17.0 +02:00
  }
  +ip: null
  +adaAmount: 0
  +tags: null
  +mentions: null
  +comments: Doctrine\ORM\PersistentCollection {#1886 …}
  +votes: Doctrine\ORM\PersistentCollection {#1973 …}
  +reports: Doctrine\ORM\PersistentCollection {#1948 …}
  +favourites: Doctrine\ORM\PersistentCollection {#1927 …}
  +notifications: Doctrine\ORM\PersistentCollection {#2442 …}
  +badges: Doctrine\ORM\PersistentCollection {#2440 …}
  +children: []
  -id: 5514
  -titleTs: "'approv':8 'destroy':3 'fda':7 'human':13 'liver':10 'receiv':6 'sound':4 'treatment':11 'tumor':2 'tumor-destroy':1 'wave':5"
  -bodyTs: null
  +cross: false
  +upVotes: 0
  +downVotes: 0
  +ranking: 1697460651
  +visibility: "visible             "
  +apId: "https://lemmy.world/post/6831355"
  +editedAt: null
  +createdAt: DateTimeImmutable @1697374251 {#1850
    date: 2023-10-15 14:50:51.0 +02:00
  }
}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS DENIED
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
3 DENIED edit
App\Entity\Entry {#2388
  +user: Proxies\__CG__\App\Entity\User {#1943 …}
  +magazine: App\Entity\Magazine {#266
    +icon: Proxies\__CG__\App\Entity\Image {#247 …}
    +name: "upliftingnews@lemmy.world"
    +title: "upliftingnews"
    +description: """
      **Welcome to /c/UpliftingNews**, a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity often found in today’s news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news that gives hope, fosters empathy, and strengthens the belief in humanity’s capacity for good.\n
      \n
      Here in /c/UpliftingNews, we uphold the values of respect, empathy, and inclusivity, fostering a supportive and vibrant community. We encourage you to share your positive news, comment, engage in uplifting conversations, and find solace in the goodness that exists around us. We are more than a news-sharing platform; we are a community built on the power of positivity and the collective desire for a more hopeful world. Remember, your small acts of kindness can be someone else’s big ray of hope. Be part of the positivity revolution; share, uplift, inspire!
      """
    +rules: null
    +subscriptionsCount: 1
    +entryCount: 479
    +entryCommentCount: 3989
    +postCount: 1
    +postCommentCount: 1
    +isAdult: false
    +customCss: null
    +lastActive: DateTime @1729387639 {#276
      date: 2024-10-20 03:27:19.0 +02:00
    }
    +markedForDeletionAt: null
    +tags: null
    +moderators: Doctrine\ORM\PersistentCollection {#238 …}
    +ownershipRequests: Doctrine\ORM\PersistentCollection {#234 …}
    +moderatorRequests: Doctrine\ORM\PersistentCollection {#223 …}
    +entries: Doctrine\ORM\PersistentCollection {#181 …}
    +posts: Doctrine\ORM\PersistentCollection {#139 …}
    +subscriptions: Doctrine\ORM\PersistentCollection {#201 …}
    +bans: Doctrine\ORM\PersistentCollection {#118 …}
    +reports: Doctrine\ORM\PersistentCollection {#104 …}
    +badges: Doctrine\ORM\PersistentCollection {#82 …}
    +logs: Doctrine\ORM\PersistentCollection {#72 …}
    +awards: Doctrine\ORM\PersistentCollection {#61 …}
    +categories: Doctrine\ORM\PersistentCollection {#1820 …}
    -id: 16
    +apId: "upliftingnews@lemmy.world"
    +apProfileId: "https://lemmy.world/c/upliftingnews"
    +apPublicUrl: "https://lemmy.world/c/upliftingnews"
    +apFollowersUrl: "https://lemmy.world/c/upliftingnews/followers"
    +apInboxUrl: "https://lemmy.world/inbox"
    +apDomain: "lemmy.world"
    +apPreferredUsername: "upliftingnews"
    +apDiscoverable: true
    +apManuallyApprovesFollowers: null
    +privateKey: null
    +publicKey: null
    +apFetchedAt: DateTime @1729583670 {#270
      date: 2024-10-22 09:54:30.0 +02:00
    }
    +apDeletedAt: null
    +apTimeoutAt: null
    +visibility: "visible             "
    +createdAt: DateTimeImmutable @1687397496 {#272
      date: 2023-06-22 03:31:36.0 +02:00
    }
  }
  +image: Proxies\__CG__\App\Entity\Image {#1962 …}
  +domain: Proxies\__CG__\App\Entity\Domain {#1924 …}
  +slug: "Tumor-destroying-sound-waves-receive-FDA-approval-for-liver-treatment-in"
  +title: "Tumor-destroying sound waves receive FDA approval for liver treatment in humans"
  +url: "https://news.umich.edu/tumor-destroying-sound-waves-receive-fda-approval-for-liver-treatment-in-humans/"
  +body: null
  +type: "link"
  +lang: "en"
  +isOc: false
  +hasEmbed: false
  +commentCount: 16
  +favouriteCount: 379
  +score: 0
  +isAdult: false
  +sticky: false
  +lastActive: DateTime @1697403497 {#2410
    date: 2023-10-15 22:58:17.0 +02:00
  }
  +ip: null
  +adaAmount: 0
  +tags: null
  +mentions: null
  +comments: Doctrine\ORM\PersistentCollection {#1886 …}
  +votes: Doctrine\ORM\PersistentCollection {#1973 …}
  +reports: Doctrine\ORM\PersistentCollection {#1948 …}
  +favourites: Doctrine\ORM\PersistentCollection {#1927 …}
  +notifications: Doctrine\ORM\PersistentCollection {#2442 …}
  +badges: Doctrine\ORM\PersistentCollection {#2440 …}
  +children: []
  -id: 5514
  -titleTs: "'approv':8 'destroy':3 'fda':7 'human':13 'liver':10 'receiv':6 'sound':4 'treatment':11 'tumor':2 'tumor-destroy':1 'wave':5"
  -bodyTs: null
  +cross: false
  +upVotes: 0
  +downVotes: 0
  +ranking: 1697460651
  +visibility: "visible             "
  +apId: "https://lemmy.world/post/6831355"
  +editedAt: null
  +createdAt: DateTimeImmutable @1697374251 {#1850
    date: 2023-10-15 14:50:51.0 +02:00
  }
}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS DENIED
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
4 DENIED moderate
App\Entity\Entry {#2388
  +user: Proxies\__CG__\App\Entity\User {#1943 …}
  +magazine: App\Entity\Magazine {#266
    +icon: Proxies\__CG__\App\Entity\Image {#247 …}
    +name: "upliftingnews@lemmy.world"
    +title: "upliftingnews"
    +description: """
      **Welcome to /c/UpliftingNews**, a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity often found in today’s news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news that gives hope, fosters empathy, and strengthens the belief in humanity’s capacity for good.\n
      \n
      Here in /c/UpliftingNews, we uphold the values of respect, empathy, and inclusivity, fostering a supportive and vibrant community. We encourage you to share your positive news, comment, engage in uplifting conversations, and find solace in the goodness that exists around us. We are more than a news-sharing platform; we are a community built on the power of positivity and the collective desire for a more hopeful world. Remember, your small acts of kindness can be someone else’s big ray of hope. Be part of the positivity revolution; share, uplift, inspire!
      """
    +rules: null
    +subscriptionsCount: 1
    +entryCount: 479
    +entryCommentCount: 3989
    +postCount: 1
    +postCommentCount: 1
    +isAdult: false
    +customCss: null
    +lastActive: DateTime @1729387639 {#276
      date: 2024-10-20 03:27:19.0 +02:00
    }
    +markedForDeletionAt: null
    +tags: null
    +moderators: Doctrine\ORM\PersistentCollection {#238 …}
    +ownershipRequests: Doctrine\ORM\PersistentCollection {#234 …}
    +moderatorRequests: Doctrine\ORM\PersistentCollection {#223 …}
    +entries: Doctrine\ORM\PersistentCollection {#181 …}
    +posts: Doctrine\ORM\PersistentCollection {#139 …}
    +subscriptions: Doctrine\ORM\PersistentCollection {#201 …}
    +bans: Doctrine\ORM\PersistentCollection {#118 …}
    +reports: Doctrine\ORM\PersistentCollection {#104 …}
    +badges: Doctrine\ORM\PersistentCollection {#82 …}
    +logs: Doctrine\ORM\PersistentCollection {#72 …}
    +awards: Doctrine\ORM\PersistentCollection {#61 …}
    +categories: Doctrine\ORM\PersistentCollection {#1820 …}
    -id: 16
    +apId: "upliftingnews@lemmy.world"
    +apProfileId: "https://lemmy.world/c/upliftingnews"
    +apPublicUrl: "https://lemmy.world/c/upliftingnews"
    +apFollowersUrl: "https://lemmy.world/c/upliftingnews/followers"
    +apInboxUrl: "https://lemmy.world/inbox"
    +apDomain: "lemmy.world"
    +apPreferredUsername: "upliftingnews"
    +apDiscoverable: true
    +apManuallyApprovesFollowers: null
    +privateKey: null
    +publicKey: null
    +apFetchedAt: DateTime @1729583670 {#270
      date: 2024-10-22 09:54:30.0 +02:00
    }
    +apDeletedAt: null
    +apTimeoutAt: null
    +visibility: "visible             "
    +createdAt: DateTimeImmutable @1687397496 {#272
      date: 2023-06-22 03:31:36.0 +02:00
    }
  }
  +image: Proxies\__CG__\App\Entity\Image {#1962 …}
  +domain: Proxies\__CG__\App\Entity\Domain {#1924 …}
  +slug: "Tumor-destroying-sound-waves-receive-FDA-approval-for-liver-treatment-in"
  +title: "Tumor-destroying sound waves receive FDA approval for liver treatment in humans"
  +url: "https://news.umich.edu/tumor-destroying-sound-waves-receive-fda-approval-for-liver-treatment-in-humans/"
  +body: null
  +type: "link"
  +lang: "en"
  +isOc: false
  +hasEmbed: false
  +commentCount: 16
  +favouriteCount: 379
  +score: 0
  +isAdult: false
  +sticky: false
  +lastActive: DateTime @1697403497 {#2410
    date: 2023-10-15 22:58:17.0 +02:00
  }
  +ip: null
  +adaAmount: 0
  +tags: null
  +mentions: null
  +comments: Doctrine\ORM\PersistentCollection {#1886 …}
  +votes: Doctrine\ORM\PersistentCollection {#1973 …}
  +reports: Doctrine\ORM\PersistentCollection {#1948 …}
  +favourites: Doctrine\ORM\PersistentCollection {#1927 …}
  +notifications: Doctrine\ORM\PersistentCollection {#2442 …}
  +badges: Doctrine\ORM\PersistentCollection {#2440 …}
  +children: []
  -id: 5514
  -titleTs: "'approv':8 'destroy':3 'fda':7 'human':13 'liver':10 'receiv':6 'sound':4 'treatment':11 'tumor':2 'tumor-destroy':1 'wave':5"
  -bodyTs: null
  +cross: false
  +upVotes: 0
  +downVotes: 0
  +ranking: 1697460651
  +visibility: "visible             "
  +apId: "https://lemmy.world/post/6831355"
  +editedAt: null
  +createdAt: DateTimeImmutable @1697374251 {#1850
    date: 2023-10-15 14:50:51.0 +02:00
  }
}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS DENIED
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
5 DENIED ROLE_USER
null
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"Symfony\Component\Security\Core\Authorization\Voter\RoleHierarchyVoter"
ACCESS DENIED
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS ABSTAIN
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
6 DENIED moderate
App\Entity\EntryComment {#3995
  +user: App\Entity\User {#3943 …}
  +entry: App\Entity\Entry {#2388
    +user: Proxies\__CG__\App\Entity\User {#1943 …}
    +magazine: App\Entity\Magazine {#266
      +icon: Proxies\__CG__\App\Entity\Image {#247 …}
      +name: "upliftingnews@lemmy.world"
      +title: "upliftingnews"
      +description: """
        **Welcome to /c/UpliftingNews**, a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity often found in today’s news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news that gives hope, fosters empathy, and strengthens the belief in humanity’s capacity for good.\n
        \n
        Here in /c/UpliftingNews, we uphold the values of respect, empathy, and inclusivity, fostering a supportive and vibrant community. We encourage you to share your positive news, comment, engage in uplifting conversations, and find solace in the goodness that exists around us. We are more than a news-sharing platform; we are a community built on the power of positivity and the collective desire for a more hopeful world. Remember, your small acts of kindness can be someone else’s big ray of hope. Be part of the positivity revolution; share, uplift, inspire!
        """
      +rules: null
      +subscriptionsCount: 1
      +entryCount: 479
      +entryCommentCount: 3989
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      Bonus!\n
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      > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
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    Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
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    Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
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      Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
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        Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
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          Bonus!\n
          \n
          > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
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          This would really be a game changer.
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        Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
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          Bonus!\n
          \n
          > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
          \n
          This would really be a game changer.
          """
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        Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
        \n
        Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
        """
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            Bonus!\n
            \n
            > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
            \n
            This would really be a game changer.
            """
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          Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
          \n
          Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
          """
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    I’m no expert, but I am familiar with the concept of “tuning” the immune system to recognize cancerous cells via pharmaceuticals. Some of these treatments may cause the immune system to attack healthy tissue. I don’t know if this is still the case.\n
    \n
    I think the difference here is that the sound treatment causes the initial disruption to the cells, and then the immune system realizes (on its own) that the cells are a threat. Then, the immune system can start attacking the bad cells.
    """
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23 DENIED edit
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            Bonus!\n
            \n
            > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
            \n
            This would really be a game changer.
            """
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          Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
          \n
          Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
          """
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      +body: "I have not heard of this obstacle"
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    +body: "Maybe I’m extrapolating incorrectly - I think that’s an obstacle because of all the news articles in the past talking about novel ways to targetedly mark cancer cells as the bad ones, and all the discussion of cancer and autoimmune disease being similar"
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    I’m no expert, but I am familiar with the concept of “tuning” the immune system to recognize cancerous cells via pharmaceuticals. Some of these treatments may cause the immune system to attack healthy tissue. I don’t know if this is still the case.\n
    \n
    I think the difference here is that the sound treatment causes the initial disruption to the cells, and then the immune system realizes (on its own) that the cells are a threat. Then, the immune system can start attacking the bad cells.
    """
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Show voter details
24 DENIED moderate
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            Bonus!\n
            \n
            > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
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            This would really be a game changer.
            """
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          Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
          \n
          Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
          """
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    +body: "Maybe I’m extrapolating incorrectly - I think that’s an obstacle because of all the news articles in the past talking about novel ways to targetedly mark cancer cells as the bad ones, and all the discussion of cancer and autoimmune disease being similar"
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    I’m no expert, but I am familiar with the concept of “tuning” the immune system to recognize cancerous cells via pharmaceuticals. Some of these treatments may cause the immune system to attack healthy tissue. I don’t know if this is still the case.\n
    \n
    I think the difference here is that the sound treatment causes the initial disruption to the cells, and then the immune system realizes (on its own) that the cells are a threat. Then, the immune system can start attacking the bad cells.
    """
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        **Welcome to /c/UpliftingNews**, a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity often found in today’s news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news that gives hope, fosters empathy, and strengthens the belief in humanity’s capacity for good.\n
        \n
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            +body: """
              Bonus!\n
              \n
              > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
              \n
              This would really be a game changer.
              """
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            Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
            \n
            Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
            """
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            date: 2023-10-15 16:14:33.0 +02:00
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        +body: "I have not heard of this obstacle"
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      I’m no expert, but I am familiar with the concept of “tuning” the immune system to recognize cancerous cells via pharmaceuticals. Some of these treatments may cause the immune system to attack healthy tissue. I don’t know if this is still the case.\n
      \n
      I think the difference here is that the sound treatment causes the initial disruption to the cells, and then the immune system realizes (on its own) that the cells are a threat. Then, the immune system can start attacking the bad cells.
      """
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    Since the sound treatment is approved by the FDA, I assume it’s safe, and it’s awesome news\n
    \n
    I can’t tell if the article is misunderstanding the science when they say it might help the immune system target the cancer cells in the future, though\n
    \n
    Most of the time I see news about it being promising in lab rats, it doesn’t work in humans - which isn’t a failing of science, it’s a failing of the media IMO
    """
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        \n
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    +title: "Tumor-destroying sound waves receive FDA approval for liver treatment in humans"
    +url: "https://news.umich.edu/tumor-destroying-sound-waves-receive-fda-approval-for-liver-treatment-in-humans/"
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            +image: null
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            +body: """
              Bonus!\n
              \n
              > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
              \n
              This would really be a game changer.
              """
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            -id: 50594
            -bodyTs: "'activ':54 'benefit':6 'beyond':8 'bodi':45 'bonus':1 'cancer':37,61 'cell':38 'changer':68 'clean':27 'clean-up':26 'continu':47 'destruct':10 'enabl':43 'fight':48 'game':67 'go':7 'help':53 'histotripsi':3 'identifi':36 'immun':31,57 'initi':50 'last':13 'learn':33 'natur':56 'pair':16 'potenti':5 'preclin':18 'process':29 'realli':64 'respons':58 'rodent':21 'studi':19 'suggest':22 'system':32 'threat':40 'tumor':9,51 'would':63 'year':14"
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              date: 2023-10-15 15:35:57.0 +02:00
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          +root: App\Entity\EntryComment {#3995}
          +body: """
            Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
            \n
            Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
            """
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            "@oDDmON@lemmy.world"
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          -id: 50647
          -bodyTs: "'approach':39 'attack':28 'cancer':19 'caus':24 'cell':30 'fight':18 'get':11 'healthi':29 'hope':1 'immun':15 'initi':48 'less':43 'like':44 'major':8 'make':41 'obstacl':9 'one':5 'person':13 'problem':52 'someth':35 'system':16 'thought':4 'understand':49 'uniqu':36 'well':32 'wrong':53"
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            date: 2023-10-15 16:14:33.0 +02:00
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        }
        +root: App\Entity\EntryComment {#3995}
        +body: "I have not heard of this obstacle"
        +lang: "en"
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          date: 2023-10-15 16:23:08.0 +02:00
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          "@oDDmON@lemmy.world"
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      +body: "Maybe I’m extrapolating incorrectly - I think that’s an obstacle because of all the news articles in the past talking about novel ways to targetedly mark cancer cells as the bad ones, and all the discussion of cancer and autoimmune disease being similar"
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        "@oDDmON@lemmy.world"
        "@ozymandias117@lemmy.world"
        "@ryannathans@aussie.zone"
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    +root: App\Entity\EntryComment {#3995}
    +body: """
      I’m no expert, but I am familiar with the concept of “tuning” the immune system to recognize cancerous cells via pharmaceuticals. Some of these treatments may cause the immune system to attack healthy tissue. I don’t know if this is still the case.\n
      \n
      I think the difference here is that the sound treatment causes the initial disruption to the cells, and then the immune system realizes (on its own) that the cells are a threat. Then, the immune system can start attacking the bad cells.
      """
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      "@ryannathans@aussie.zone"
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    Since the sound treatment is approved by the FDA, I assume it’s safe, and it’s awesome news\n
    \n
    I can’t tell if the article is misunderstanding the science when they say it might help the immune system target the cancer cells in the future, though\n
    \n
    Most of the time I see news about it being promising in lab rats, it doesn’t work in humans - which isn’t a failing of science, it’s a failing of the media IMO
    """
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    "@magicalman315@lemmy.world"
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        \n
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        """
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            +body: """
              Bonus!\n
              \n
              > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
              \n
              This would really be a game changer.
              """
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            Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
            \n
            Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
            """
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        +body: "I have not heard of this obstacle"
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      +body: "Maybe I’m extrapolating incorrectly - I think that’s an obstacle because of all the news articles in the past talking about novel ways to targetedly mark cancer cells as the bad ones, and all the discussion of cancer and autoimmune disease being similar"
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      I’m no expert, but I am familiar with the concept of “tuning” the immune system to recognize cancerous cells via pharmaceuticals. Some of these treatments may cause the immune system to attack healthy tissue. I don’t know if this is still the case.\n
      \n
      I think the difference here is that the sound treatment causes the initial disruption to the cells, and then the immune system realizes (on its own) that the cells are a threat. Then, the immune system can start attacking the bad cells.
      """
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    Since the sound treatment is approved by the FDA, I assume it’s safe, and it’s awesome news\n
    \n
    I can’t tell if the article is misunderstanding the science when they say it might help the immune system target the cancer cells in the future, though\n
    \n
    Most of the time I see news about it being promising in lab rats, it doesn’t work in humans - which isn’t a failing of science, it’s a failing of the media IMO
    """
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          Bonus!\n
          \n
          > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
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          This would really be a game changer.
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        Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
        \n
        Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
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    It is a general obstacle. Cancer cells are basically normal cells have mutated in such a way that they a) still survive, b) subdivide rampantly and c) fly under the radar of white blood cells, which normally pick up and deal with said anomalies before they become a problem.\n
    \n
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          Bonus!\n
          \n
          > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
          \n
          This would really be a game changer.
          """
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        Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
        \n
        Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
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    It is a general obstacle. Cancer cells are basically normal cells have mutated in such a way that they a) still survive, b) subdivide rampantly and c) fly under the radar of white blood cells, which normally pick up and deal with said anomalies before they become a problem.\n
    \n
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          Bonus!\n
          \n
          > And histotripsy’s potential benefits go beyond tumor destruction. In the last year, a pair of preclinical studies in rodents suggest that in the clean-up process, the immune system learns how to identify cancer cells as threats. This can enable the body to continue fighting the initial tumor and help activate a natural immune response to the cancer.\n
          \n
          This would really be a game changer.
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        Hopefully, but I thought one of the major obstacles of getting a person’s immune system to fight cancer was that it has caused it to then attack healthy cells as well\n
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        Is there something unique about this approach that makes this less likely, or is my initial understanding of the problem wrong?
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    It is a general obstacle. Cancer cells are basically normal cells have mutated in such a way that they a) still survive, b) subdivide rampantly and c) fly under the radar of white blood cells, which normally pick up and deal with said anomalies before they become a problem.\n
    \n
    So the trick is about getting white blood cells to detect amd attack anomalies that it previously wouldn't, while not attacking healthy cells.
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    The sound waves are focused onto the tumor, so they only have enough energy to damage tissue there, and not anywhere else.\n
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    The sound waves are focused onto the tumor, so they only have enough energy to damage tissue there, and not anywhere else.\n
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    Think about focusing the sun’s rays through a magnifying glass; they’re only concentrated enough to burn at a very small area. The focused ultrasound is similar, although they’re probably using some form of phased array to get the equivalent effect.
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    The sound waves are focused onto the tumor, so they only have enough energy to damage tissue there, and not anywhere else.\n
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    Think about focusing the sun’s rays through a magnifying glass; they’re only concentrated enough to burn at a very small area. The focused ultrasound is similar, although they’re probably using some form of phased array to get the equivalent effect.
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    This is my non expert opinion but based on what I know about sound waves I think this is how they are doing it. Hopefully someone more knowledgeable can chip in with more sources.\n
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    It looks like you can target and focus the sound waves to converge and only be strong enough to trigger the cavitation effect in tumorous areas . The cavitation creates tiny bubbles and damage the tissue only in the focus area.\n
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    It’s similar to how radiotherapy works in that it’s concentrated damage in a targeted area, but less much less damaging to other tissue that it passes through.\n
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Show voter details
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50 DENIED moderate
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Show voter details
52 DENIED moderate
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Show voter details
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Show voter details
56 DENIED moderate
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Show voter details
57 DENIED ROLE_USER
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Show voter details
58 DENIED moderate
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Show voter details
68 DENIED moderate
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Show voter details
69 DENIED edit
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    **Welcome to /c/UpliftingNews**, a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity often found in today’s news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news that gives hope, fosters empathy, and strengthens the belief in humanity’s capacity for good.\n
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    Here in /c/UpliftingNews, we uphold the values of respect, empathy, and inclusivity, fostering a supportive and vibrant community. We encourage you to share your positive news, comment, engage in uplifting conversations, and find solace in the goodness that exists around us. We are more than a news-sharing platform; we are a community built on the power of positivity and the collective desire for a more hopeful world. Remember, your small acts of kindness can be someone else’s big ray of hope. Be part of the positivity revolution; share, uplift, inspire!
    """
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