Security

Token

There is no security token.

Firewall

main Name
Security enabled
Stateless

Configuration

Key Value
provider security.user.provider.concrete.app_user_provider
context main
entry_point App\Security\KbinAuthenticator
user_checker App\Security\UserChecker
access_denied_handler (none)
access_denied_url (none)
authenticators
[
  "two_factor"
  "remember_me"
  "App\Security\KbinAuthenticator"
  "App\Security\FacebookAuthenticator"
  "App\Security\GoogleAuthenticator"
  "App\Security\GithubAuthenticator"
  "App\Security\KeycloakAuthenticator"
]

Listeners

Listener Duration Response
Symfony\Component\Security\Http\Firewall\ChannelListener {#723
  -map: Symfony\Component\Security\Http\AccessMap {#722 …}
  -logger: Monolog\Logger {#783 …}
  -httpPort: 80
  -httpsPort: 443
}
0.00 ms (none)
Symfony\Component\Security\Http\Firewall\ContextListener {#706
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\TokenStorage {#1017 …}
  -sessionKey: "_security_main"
  -logger: Monolog\Logger {#783 …}
  -userProviders: Symfony\Component\DependencyInjection\Argument\RewindableGenerator {#705 …}
  -dispatcher: Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher {#747 …}
  -registered: false
  -trustResolver: Scheb\TwoFactorBundle\Security\Authentication\AuthenticationTrustResolver {#780 …}
  -sessionTrackerEnabler: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage::enableUsageTracking(): void {#703 …}
}
6.70 ms (none)
Symfony\Component\Security\Http\Firewall\AuthenticatorManagerListener {#584
  -authenticatorManager: Symfony\Component\Security\Http\Authentication\AuthenticatorManager {#595 …}
}
0.00 ms (none)
Scheb\TwoFactorBundle\Security\Http\Firewall\TwoFactorAccessListener {#582
  -twoFactorFirewallConfig: Scheb\TwoFactorBundle\Security\TwoFactor\TwoFactorFirewallConfig {#842 …}
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -twoFactorAccessDecider: Scheb\TwoFactorBundle\Security\Authorization\TwoFactorAccessDecider {#581 …}
}
0.06 ms (none)
Symfony\Component\Security\Http\Firewall\AccessListener {#579
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -accessDecisionManager: Symfony\Component\Security\Core\Authorization\TraceableAccessDecisionManager {#937 …}
  -map: Symfony\Component\Security\Http\AccessMap {#722 …}
}
0.00 ms (none)
Symfony\Component\Security\Http\Firewall\LogoutListener {#786
  -tokenStorage: Symfony\Component\Security\Core\Authentication\Token\Storage\UsageTrackingTokenStorage {#1018 …}
  -options: [
    "csrf_parameter" => "_csrf_token"
    "csrf_token_id" => "logout"
    "logout_path" => "app_logout"
  ]
  -httpUtils: Symfony\Component\Security\Http\HttpUtils {#841 …}
  -csrfTokenManager: Symfony\Component\Security\Csrf\CsrfTokenManager {#1015 …}
  -eventDispatcher: Symfony\Component\EventDispatcher\Debug\TraceableEventDispatcher {#747 …}
}
0.00 ms (none)

Authenticators

No authenticators have been recorded. Check previous profiles on your authentication endpoint.

Access Decision

affirmative Strategy
# Voter class
1
"Symfony\Component\Security\Core\Authorization\Voter\AuthenticatedVoter"
2
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
3
"Symfony\Component\Security\Core\Authorization\Voter\RoleHierarchyVoter"
4
"Symfony\Component\Security\Core\Authorization\Voter\ExpressionVoter"
5
"App\Security\Voter\EntryCommentVoter"
6
"App\Security\Voter\EntryVoter"
7
"App\Security\Voter\MagazineVoter"
8
"App\Security\Voter\MessageThreadVoter"
9
"App\Security\Voter\MessageVoter"
10
"App\Security\Voter\NotificationVoter"
11
"App\Security\Voter\OAuth2UserConsentVoter"
12
"App\Security\Voter\PostCommentVoter"
13
"App\Security\Voter\PostVoter"
14
"App\Security\Voter\UserVoter"

Access decision log

# Result Attributes Object
1 DENIED ROLE_USER
null
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"Symfony\Component\Security\Core\Authorization\Voter\RoleHierarchyVoter"
ACCESS DENIED
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS ABSTAIN
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
2 DENIED moderate
App\Entity\Entry {#2400
  +user: Proxies\__CG__\App\Entity\User {#1978 …}
  +magazine: App\Entity\Magazine {#265
    +icon: Proxies\__CG__\App\Entity\Image {#246 …}
    +name: "asklemmy@lemmy.world"
    +title: "asklemmy"
    +description: """
      A Fediverse community for open-ended, thought provoking questions\n
      -----------------------------------------------------------------\n
      \n
      ---\n
      \n
      **Rules: (interactive)**\n
      ------------------------\n
      \n
      ---\n
      \n
      1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
      \n
      ---\n
      \n
      2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
      \n
      ---\n
      \n
      3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
      \n
      ---\n
      \n
      4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
      \n
      ---\n
      \n
      5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
      \n
      ---\n
      \n
      Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
      \n
      Partnered Communities:\n
      ----------------------\n
      \n
      [Tech Support](/c/techsupport@lemmy.world)\n
      \n
      [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
      \n
      [You Should Know](/c/youshouldknow@lemmy.world)\n
      \n
      [Reddit](/c/reddit@lemmy.world)\n
      \n
      [Jokes](/c/jokes@lemmy.world)\n
      \n
      [Ask Ouija](/c/askouija@lemmy.world)\n
      \n
      ---\n
      \n
      Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
      \n
      ---\n
      \n
      ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
      """
    +rules: null
    +subscriptionsCount: 1
    +entryCount: 1179
    +entryCommentCount: 42676
    +postCount: 3
    +postCommentCount: 67
    +isAdult: false
    +customCss: null
    +lastActive: DateTime @1729583245 {#275
      date: 2024-10-22 09:47:25.0 +02:00
    }
    +markedForDeletionAt: null
    +tags: null
    +moderators: Doctrine\ORM\PersistentCollection {#237 …}
    +ownershipRequests: Doctrine\ORM\PersistentCollection {#233 …}
    +moderatorRequests: Doctrine\ORM\PersistentCollection {#222 …}
    +entries: Doctrine\ORM\PersistentCollection {#180 …}
    +posts: Doctrine\ORM\PersistentCollection {#138 …}
    +subscriptions: Doctrine\ORM\PersistentCollection {#200 …}
    +bans: Doctrine\ORM\PersistentCollection {#117 …}
    +reports: Doctrine\ORM\PersistentCollection {#103 …}
    +badges: Doctrine\ORM\PersistentCollection {#81 …}
    +logs: Doctrine\ORM\PersistentCollection {#71 …}
    +awards: Doctrine\ORM\PersistentCollection {#1346 …}
    +categories: Doctrine\ORM\PersistentCollection {#1823 …}
    -id: 49
    +apId: "asklemmy@lemmy.world"
    +apProfileId: "https://lemmy.world/c/asklemmy"
    +apPublicUrl: "https://lemmy.world/c/asklemmy"
    +apFollowersUrl: "https://lemmy.world/c/asklemmy/followers"
    +apInboxUrl: "https://lemmy.world/inbox"
    +apDomain: "lemmy.world"
    +apPreferredUsername: "asklemmy"
    +apDiscoverable: true
    +apManuallyApprovesFollowers: null
    +privateKey: null
    +publicKey: null
    +apFetchedAt: DateTime @1729583301 {#269
      date: 2024-10-22 09:48:21.0 +02:00
    }
    +apDeletedAt: null
    +apTimeoutAt: null
    +visibility: "visible             "
    +createdAt: DateTimeImmutable @1697177027 {#271
      date: 2023-10-13 08:03:47.0 +02:00
    }
  }
  +image: null
  +domain: Proxies\__CG__\App\Entity\Domain {#1889 …}
  +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
  +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
  +url: null
  +body: """
    > **Generic name (Brand/street name)**\n
    \n
    Discussion paragraphs/submission\n
    \n
    ---\n
    \n
    *If you are curious about a specific substance but can’t answer, please follow this format—\n
    \n
    > **Generic name (Brand/street name)**\n
    \n
    [relevant keywords associated]
    """
  +type: "article"
  +lang: "en"
  +isOc: false
  +hasEmbed: false
  +commentCount: 60
  +favouriteCount: 21
  +score: 0
  +isAdult: false
  +sticky: false
  +lastActive: DateTime @1701928342 {#2414
    date: 2023-12-07 06:52:22.0 +01:00
  }
  +ip: null
  +adaAmount: 0
  +tags: null
  +mentions: null
  +comments: Doctrine\ORM\PersistentCollection {#1688 …}
  +votes: Doctrine\ORM\PersistentCollection {#1966 …}
  +reports: Doctrine\ORM\PersistentCollection {#1965 …}
  +favourites: Doctrine\ORM\PersistentCollection {#1368 …}
  +notifications: Doctrine\ORM\PersistentCollection {#2426 …}
  +badges: Doctrine\ORM\PersistentCollection {#2439 …}
  +children: []
  -id: 20756
  -titleTs: "'bold':16 'brand/street':19 'experiment':1 'folk':23 'gem':6 'hidden':5 'ideal':12 'make':10 'medications/drugs/substances':7 'name':18,20 'new':21 'paragraph':22 'substanc':17 'usecas':15"
  -bodyTs: "'answer':18 'associ':29 'brand/street':3,25 'curious':10 'discuss':5 'follow':20 'format':22 'generic':1,23 'keyword':28 'name':2,4,24,26 'paragraphs/submission':6 'pleas':19 'relev':27 'specif':13 'substanc':14"
  +cross: false
  +upVotes: 0
  +downVotes: 0
  +ranking: 1701990636
  +visibility: "visible             "
  +apId: "https://lemmy.world/post/9238615"
  +editedAt: DateTimeImmutable @1703295886 {#1793
    date: 2023-12-23 02:44:46.0 +01:00
  }
  +createdAt: DateTimeImmutable @1701904236 {#2402
    date: 2023-12-07 00:10:36.0 +01:00
  }
}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS DENIED
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
3 DENIED edit
App\Entity\Entry {#2400
  +user: Proxies\__CG__\App\Entity\User {#1978 …}
  +magazine: App\Entity\Magazine {#265
    +icon: Proxies\__CG__\App\Entity\Image {#246 …}
    +name: "asklemmy@lemmy.world"
    +title: "asklemmy"
    +description: """
      A Fediverse community for open-ended, thought provoking questions\n
      -----------------------------------------------------------------\n
      \n
      ---\n
      \n
      **Rules: (interactive)**\n
      ------------------------\n
      \n
      ---\n
      \n
      1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
      \n
      ---\n
      \n
      2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
      \n
      ---\n
      \n
      3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
      \n
      ---\n
      \n
      4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
      \n
      ---\n
      \n
      5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
      \n
      ---\n
      \n
      Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
      \n
      Partnered Communities:\n
      ----------------------\n
      \n
      [Tech Support](/c/techsupport@lemmy.world)\n
      \n
      [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
      \n
      [You Should Know](/c/youshouldknow@lemmy.world)\n
      \n
      [Reddit](/c/reddit@lemmy.world)\n
      \n
      [Jokes](/c/jokes@lemmy.world)\n
      \n
      [Ask Ouija](/c/askouija@lemmy.world)\n
      \n
      ---\n
      \n
      Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
      \n
      ---\n
      \n
      ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
      """
    +rules: null
    +subscriptionsCount: 1
    +entryCount: 1179
    +entryCommentCount: 42676
    +postCount: 3
    +postCommentCount: 67
    +isAdult: false
    +customCss: null
    +lastActive: DateTime @1729583245 {#275
      date: 2024-10-22 09:47:25.0 +02:00
    }
    +markedForDeletionAt: null
    +tags: null
    +moderators: Doctrine\ORM\PersistentCollection {#237 …}
    +ownershipRequests: Doctrine\ORM\PersistentCollection {#233 …}
    +moderatorRequests: Doctrine\ORM\PersistentCollection {#222 …}
    +entries: Doctrine\ORM\PersistentCollection {#180 …}
    +posts: Doctrine\ORM\PersistentCollection {#138 …}
    +subscriptions: Doctrine\ORM\PersistentCollection {#200 …}
    +bans: Doctrine\ORM\PersistentCollection {#117 …}
    +reports: Doctrine\ORM\PersistentCollection {#103 …}
    +badges: Doctrine\ORM\PersistentCollection {#81 …}
    +logs: Doctrine\ORM\PersistentCollection {#71 …}
    +awards: Doctrine\ORM\PersistentCollection {#1346 …}
    +categories: Doctrine\ORM\PersistentCollection {#1823 …}
    -id: 49
    +apId: "asklemmy@lemmy.world"
    +apProfileId: "https://lemmy.world/c/asklemmy"
    +apPublicUrl: "https://lemmy.world/c/asklemmy"
    +apFollowersUrl: "https://lemmy.world/c/asklemmy/followers"
    +apInboxUrl: "https://lemmy.world/inbox"
    +apDomain: "lemmy.world"
    +apPreferredUsername: "asklemmy"
    +apDiscoverable: true
    +apManuallyApprovesFollowers: null
    +privateKey: null
    +publicKey: null
    +apFetchedAt: DateTime @1729583301 {#269
      date: 2024-10-22 09:48:21.0 +02:00
    }
    +apDeletedAt: null
    +apTimeoutAt: null
    +visibility: "visible             "
    +createdAt: DateTimeImmutable @1697177027 {#271
      date: 2023-10-13 08:03:47.0 +02:00
    }
  }
  +image: null
  +domain: Proxies\__CG__\App\Entity\Domain {#1889 …}
  +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
  +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
  +url: null
  +body: """
    > **Generic name (Brand/street name)**\n
    \n
    Discussion paragraphs/submission\n
    \n
    ---\n
    \n
    *If you are curious about a specific substance but can’t answer, please follow this format—\n
    \n
    > **Generic name (Brand/street name)**\n
    \n
    [relevant keywords associated]
    """
  +type: "article"
  +lang: "en"
  +isOc: false
  +hasEmbed: false
  +commentCount: 60
  +favouriteCount: 21
  +score: 0
  +isAdult: false
  +sticky: false
  +lastActive: DateTime @1701928342 {#2414
    date: 2023-12-07 06:52:22.0 +01:00
  }
  +ip: null
  +adaAmount: 0
  +tags: null
  +mentions: null
  +comments: Doctrine\ORM\PersistentCollection {#1688 …}
  +votes: Doctrine\ORM\PersistentCollection {#1966 …}
  +reports: Doctrine\ORM\PersistentCollection {#1965 …}
  +favourites: Doctrine\ORM\PersistentCollection {#1368 …}
  +notifications: Doctrine\ORM\PersistentCollection {#2426 …}
  +badges: Doctrine\ORM\PersistentCollection {#2439 …}
  +children: []
  -id: 20756
  -titleTs: "'bold':16 'brand/street':19 'experiment':1 'folk':23 'gem':6 'hidden':5 'ideal':12 'make':10 'medications/drugs/substances':7 'name':18,20 'new':21 'paragraph':22 'substanc':17 'usecas':15"
  -bodyTs: "'answer':18 'associ':29 'brand/street':3,25 'curious':10 'discuss':5 'follow':20 'format':22 'generic':1,23 'keyword':28 'name':2,4,24,26 'paragraphs/submission':6 'pleas':19 'relev':27 'specif':13 'substanc':14"
  +cross: false
  +upVotes: 0
  +downVotes: 0
  +ranking: 1701990636
  +visibility: "visible             "
  +apId: "https://lemmy.world/post/9238615"
  +editedAt: DateTimeImmutable @1703295886 {#1793
    date: 2023-12-23 02:44:46.0 +01:00
  }
  +createdAt: DateTimeImmutable @1701904236 {#2402
    date: 2023-12-07 00:10:36.0 +01:00
  }
}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS DENIED
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
4 DENIED moderate
App\Entity\Entry {#2400
  +user: Proxies\__CG__\App\Entity\User {#1978 …}
  +magazine: App\Entity\Magazine {#265
    +icon: Proxies\__CG__\App\Entity\Image {#246 …}
    +name: "asklemmy@lemmy.world"
    +title: "asklemmy"
    +description: """
      A Fediverse community for open-ended, thought provoking questions\n
      -----------------------------------------------------------------\n
      \n
      ---\n
      \n
      **Rules: (interactive)**\n
      ------------------------\n
      \n
      ---\n
      \n
      1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
      \n
      ---\n
      \n
      2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
      \n
      ---\n
      \n
      3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
      \n
      ---\n
      \n
      4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
      \n
      ---\n
      \n
      5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
      \n
      ---\n
      \n
      Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
      \n
      Partnered Communities:\n
      ----------------------\n
      \n
      [Tech Support](/c/techsupport@lemmy.world)\n
      \n
      [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
      \n
      [You Should Know](/c/youshouldknow@lemmy.world)\n
      \n
      [Reddit](/c/reddit@lemmy.world)\n
      \n
      [Jokes](/c/jokes@lemmy.world)\n
      \n
      [Ask Ouija](/c/askouija@lemmy.world)\n
      \n
      ---\n
      \n
      Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
      \n
      ---\n
      \n
      ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
      """
    +rules: null
    +subscriptionsCount: 1
    +entryCount: 1179
    +entryCommentCount: 42676
    +postCount: 3
    +postCommentCount: 67
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        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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Show voter details
9 DENIED ROLE_USER
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10 DENIED moderate
App\Entity\EntryComment {#4075
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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    > **Coenzyme Q10**\n
    \n
    Energy, mitochondrial support, antioxidant\n
    \n
    Personally, I think everyone should be taking this. Extremely safe, improves cardiac outcomes, some evidence that it can reverse damage in chronic kidney disease. Most people won’t feel different, but I take high dose CoQ10 for mitochondrial dysfunction, and I can tell you it definitely has a huge impact. Love this stuff.\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC8092430/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092430/)\n
    \n
    [www.mdpi.com/2076-3921/8/2/44#:~:text=Chronic Kid…](https://www.mdpi.com/2076-3921/8/2/44#:~:text=Chronic%20Kidney%20Disease%20(CKD),-The%20role%20of&text=There%20is%20evidence%20that%20CoQ10,dialysis%20in%20patients%20with%20CKD).
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Show voter details
11 DENIED edit
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        \n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        \n
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        \n
        ---\n
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        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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14 DENIED moderate
App\Entity\EntryComment {#4157
  +user: App\Entity\User {#4058 …}
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    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
    +url: null
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      \n
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      \n
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  +magazine: App\Entity\Magazine {#265}
  +image: null
  +parent: null
  +root: null
  +body: """
    > **Apigenin (herbal supplement)**\n
    \n
    Insomnia, anxiety\n
    \n
    Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
    """
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    date: 2023-12-07 04:15:02.0 +01:00
  }
}
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ACCESS ABSTAIN
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ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
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ACCESS ABSTAIN
Show voter details
15 DENIED edit
App\Entity\EntryComment {#4157
  +user: App\Entity\User {#4058 …}
  +entry: App\Entity\Entry {#2400
    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
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        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
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      Discussion paragraphs/submission\n
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      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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    +createdAt: DateTimeImmutable @1701904236 {#2402
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  }
  +magazine: App\Entity\Magazine {#265}
  +image: null
  +parent: null
  +root: null
  +body: """
    > **Apigenin (herbal supplement)**\n
    \n
    Insomnia, anxiety\n
    \n
    Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
    """
  +lang: "en"
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ACCESS ABSTAIN
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ACCESS DENIED
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
Show voter details
16 DENIED moderate
App\Entity\EntryComment {#4157
  +user: App\Entity\User {#4058 …}
  +entry: App\Entity\Entry {#2400
    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
      +rules: null
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        \n
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        \n
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        \n
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        \n
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        \n
        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        ---\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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      Discussion paragraphs/submission\n
      \n
      ---\n
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      \n
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      \n
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        \n
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        \n
        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
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  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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}
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Show voter details
23 DENIED edit
App\Entity\EntryComment {#4606
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    +user: Proxies\__CG__\App\Entity\User {#1978 …}
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      +title: "asklemmy"
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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        > **Apigenin (herbal supplement)**\n
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        Insomnia, anxiety\n
        \n
        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
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  +root: App\Entity\EntryComment {#4157}
  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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}
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ACCESS DENIED
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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Show voter details
24 DENIED moderate
App\Entity\EntryComment {#4606
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      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
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        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
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  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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  +body: "Thanks! Is it expensive? How much do you get?"
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Show voter details
27 DENIED edit
App\Entity\EntryComment {#4674
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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          > **Apigenin (herbal supplement)**\n
          \n
          Insomnia, anxiety\n
          \n
          Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
          """
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      +body: "Was curious about this since Andrew Huberman mentioned it"
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    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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  +body: "Thanks! Is it expensive? How much do you get?"
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Show voter details
28 DENIED moderate
App\Entity\EntryComment {#4674
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      +title: "asklemmy"
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        date: 2023-10-13 08:03:47.0 +02:00
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
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      > **Generic name (Brand/street name)**\n
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      Discussion paragraphs/submission\n
      \n
      ---\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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          > **Apigenin (herbal supplement)**\n
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          Insomnia, anxiety\n
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          Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
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    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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  +body: "Thanks! Is it expensive? How much do you get?"
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
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      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
    \n
    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
    """
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}
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ACCESS ABSTAIN
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Show voter details
31 DENIED edit
App\Entity\EntryComment {#4728
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      +title: "asklemmy"
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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  +magazine: App\Entity\Magazine {#265}
  +image: null
  +parent: App\Entity\EntryComment {#4674
    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +entry: App\Entity\Entry {#2400}
    +magazine: App\Entity\Magazine {#265}
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    +parent: App\Entity\EntryComment {#4606
      +user: App\Entity\User {#4058 …}
      +entry: App\Entity\Entry {#2400}
      +magazine: App\Entity\Magazine {#265}
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        +parent: App\Entity\EntryComment {#4157
          +user: App\Entity\User {#4058 …}
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          +magazine: App\Entity\Magazine {#265}
          +image: null
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          +body: """
            > **Apigenin (herbal supplement)**\n
            \n
            Insomnia, anxiety\n
            \n
            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
            """
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            date: 2023-12-07 04:15:02.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Was curious about this since Andrew Huberman mentioned it"
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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        date: 2023-12-07 04:25:07.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Thanks! Is it expensive? How much do you get?"
    +lang: "en"
    +isAdult: false
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      "@Chetzemoka@startrek.website"
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    +children: Doctrine\ORM\PersistentCollection {#4675 …}
    +nested: Doctrine\ORM\PersistentCollection {#4677 …}
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      date: 2023-12-07 04:26:04.0 +01:00
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: """
    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
    \n
    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
    """
  +lang: "en"
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    date: 2023-12-07 04:43:04.0 +01:00
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    "@Chetzemoka@startrek.website"
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  +children: Doctrine\ORM\PersistentCollection {#4729 …}
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}
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Show voter details
32 DENIED moderate
App\Entity\EntryComment {#4728
  +user: App\Entity\User {#4058 …}
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    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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            > **Apigenin (herbal supplement)**\n
            \n
            Insomnia, anxiety\n
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            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
            """
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        +body: "Was curious about this since Andrew Huberman mentioned it"
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      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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    +body: "Thanks! Is it expensive? How much do you get?"
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    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
    \n
    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
    """
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        +user: App\Entity\User {#4058 …}
        +entry: App\Entity\Entry {#2400}
        +magazine: App\Entity\Magazine {#265}
        +image: null
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              > **Apigenin (herbal supplement)**\n
              \n
              Insomnia, anxiety\n
              \n
              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
              """
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              date: 2023-12-07 04:15:02.0 +01:00
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          +body: "Was curious about this since Andrew Huberman mentioned it"
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        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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      +body: "Thanks! Is it expensive? How much do you get?"
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    +body: """
      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
      \n
      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
      """
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  +body: "Is that the dose, 1/night before bed?"
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35 DENIED edit
App\Entity\EntryComment {#4765
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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              > **Apigenin (herbal supplement)**\n
              \n
              Insomnia, anxiety\n
              \n
              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
              """
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        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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    +body: """
      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
      \n
      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
      """
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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              > **Apigenin (herbal supplement)**\n
              \n
              Insomnia, anxiety\n
              \n
              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
              """
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          +body: "Was curious about this since Andrew Huberman mentioned it"
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        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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      +body: "Thanks! Is it expensive? How much do you get?"
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    +body: """
      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
      \n
      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
      """
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ACCESS ABSTAIN
Show voter details
37 DENIED ROLE_USER
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ACCESS ABSTAIN
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ACCESS DENIED
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
Show voter details
38 DENIED moderate
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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    +body: """
      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
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      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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      > **Generic name (Brand/street name)**\n
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  +magazine: App\Entity\Magazine {#265}
  +image: null
  +parent: App\Entity\EntryComment {#4765
    +user: Proxies\__CG__\App\Entity\User {#1978 …}
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    +magazine: App\Entity\Magazine {#265}
    +image: null
    +parent: App\Entity\EntryComment {#4728
      +user: App\Entity\User {#4058 …}
      +entry: App\Entity\Entry {#2400}
      +magazine: App\Entity\Magazine {#265}
      +image: null
      +parent: App\Entity\EntryComment {#4674
        +user: Proxies\__CG__\App\Entity\User {#1978 …}
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        +magazine: App\Entity\Magazine {#265}
        +image: null
        +parent: App\Entity\EntryComment {#4606
          +user: App\Entity\User {#4058 …}
          +entry: App\Entity\Entry {#2400}
          +magazine: App\Entity\Magazine {#265}
          +image: null
          +parent: App\Entity\EntryComment {#4506
            +user: Proxies\__CG__\App\Entity\User {#1978 …}
            +entry: App\Entity\Entry {#2400}
            +magazine: App\Entity\Magazine {#265}
            +image: null
            +parent: App\Entity\EntryComment {#4157
              +user: App\Entity\User {#4058 …}
              +entry: App\Entity\Entry {#2400}
              +magazine: App\Entity\Magazine {#265}
              +image: null
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              +body: """
                > **Apigenin (herbal supplement)**\n
                \n
                Insomnia, anxiety\n
                \n
                Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                """
              +lang: "en"
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                date: 2023-12-23 01:53:45.0 +01:00
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                "@cheese_greater@lemmy.world"
              ]
              +children: Doctrine\ORM\PersistentCollection {#4158 …}
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              -id: 205080
              -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
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                date: 2023-12-22 23:57:18.0 +01:00
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                date: 2023-12-07 04:15:02.0 +01:00
              }
            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Was curious about this since Andrew Huberman mentioned it"
            +lang: "en"
            +isAdult: false
            +favouriteCount: 1
            +score: 0
            +lastActive: DateTime @1701919366 {#4504
              date: 2023-12-07 04:22:46.0 +01:00
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
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            +children: Doctrine\ORM\PersistentCollection {#4507 …}
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            -bodyTs: "'andrew':6 'curious':2 'huberman':7 'mention':8 'sinc':5"
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              date: 2023-12-07 04:22:46.0 +01:00
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
          +lang: "en"
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
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          -id: 205119
          -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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            date: 2023-12-07 04:25:07.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Thanks! Is it expensive? How much do you get?"
        +lang: "en"
        +isAdult: false
        +favouriteCount: 2
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          date: 2023-12-07 04:26:04.0 +01:00
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          "@cheese_greater@lemmy.world"
          "@Chetzemoka@startrek.website"
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          date: 2023-12-22 23:55:09.0 +01:00
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          date: 2023-12-07 04:26:04.0 +01:00
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: """
        Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
        \n
        I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
        """
      +lang: "en"
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        date: 2023-12-07 04:43:04.0 +01:00
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        "@Chetzemoka@startrek.website"
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      -id: 205159
      -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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        date: 2023-12-07 04:43:04.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Is that the dose, 1/night before bed?"
    +lang: "en"
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      "@Chetzemoka@startrek.website"
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      date: 2023-12-07 04:45:44.0 +01:00
    }
  }
  +root: App\Entity\EntryComment {#4157}
  +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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    "@Chetzemoka@startrek.website"
  ]
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  +createdAt: DateTimeImmutable @1701920820 {#4781
    date: 2023-12-07 04:47:00.0 +01:00
  }
}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryCommentVoter"
ACCESS DENIED
"App\Security\Voter\EntryVoter"
ACCESS ABSTAIN
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
39 DENIED edit
App\Entity\EntryComment {#4779
  +user: App\Entity\User {#4058 …}
  +entry: App\Entity\Entry {#2400
    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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                > **Apigenin (herbal supplement)**\n
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                Insomnia, anxiety\n
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                Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                """
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            +body: "Was curious about this since Andrew Huberman mentioned it"
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          +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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        +body: "Thanks! Is it expensive? How much do you get?"
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      +body: """
        Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
        \n
        I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
        """
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    +body: "Is that the dose, 1/night before bed?"
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  +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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    -id: 20756
    -titleTs: "'bold':16 'brand/street':19 'experiment':1 'folk':23 'gem':6 'hidden':5 'ideal':12 'make':10 'medications/drugs/substances':7 'name':18,20 'new':21 'paragraph':22 'substanc':17 'usecas':15"
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              +body: """
                > **Apigenin (herbal supplement)**\n
                \n
                Insomnia, anxiety\n
                \n
                Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                """
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            +body: "Was curious about this since Andrew Huberman mentioned it"
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          +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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        +body: "Thanks! Is it expensive? How much do you get?"
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      +body: """
        Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
        \n
        I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
        """
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    +body: "Is that the dose, 1/night before bed?"
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  +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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        \n
        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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                +body: """
                  > **Apigenin (herbal supplement)**\n
                  \n
                  Insomnia, anxiety\n
                  \n
                  Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                  """
                +lang: "en"
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                  date: 2023-12-23 01:53:45.0 +01:00
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                  date: 2023-12-22 23:57:18.0 +01:00
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                  date: 2023-12-07 04:15:02.0 +01:00
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Was curious about this since Andrew Huberman mentioned it"
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                date: 2023-12-07 04:22:46.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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          +root: App\Entity\EntryComment {#4157}
          +body: "Thanks! Is it expensive? How much do you get?"
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            date: 2023-12-07 04:26:04.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: """
          Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
          \n
          I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
          """
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      +body: "Is that the dose, 1/night before bed?"
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    +root: App\Entity\EntryComment {#4157}
    +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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Show voter details
43 DENIED edit
App\Entity\EntryComment {#4815
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        A Fediverse community for open-ended, thought provoking questions\n
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        **Rules: (interactive)**\n
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        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
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      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
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      [relevant keywords associated]
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                +body: """
                  > **Apigenin (herbal supplement)**\n
                  \n
                  Insomnia, anxiety\n
                  \n
                  Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                  """
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                  date: 2023-12-07 04:15:02.0 +01:00
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              +root: App\Entity\EntryComment {#4157}
              +body: "Was curious about this since Andrew Huberman mentioned it"
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            +root: App\Entity\EntryComment {#4157}
            +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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          +body: "Thanks! Is it expensive? How much do you get?"
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        +body: """
          Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
          \n
          I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
          """
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      +body: "Is that the dose, 1/night before bed?"
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    +root: App\Entity\EntryComment {#4157}
    +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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  +root: App\Entity\EntryComment {#4157}
  +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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                  > **Apigenin (herbal supplement)**\n
                  \n
                  Insomnia, anxiety\n
                  \n
                  Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                  """
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              +body: "Was curious about this since Andrew Huberman mentioned it"
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            +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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            -id: 205119
            -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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              date: 2023-12-07 04:25:07.0 +01:00
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          +body: "Thanks! Is it expensive? How much do you get?"
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            "@Chetzemoka@startrek.website"
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            date: 2023-12-22 23:55:09.0 +01:00
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            date: 2023-12-07 04:26:04.0 +01:00
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        +root: App\Entity\EntryComment {#4157}
        +body: """
          Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
          \n
          I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
          """
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      +body: "Is that the dose, 1/night before bed?"
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    +root: App\Entity\EntryComment {#4157}
    +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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      date: 2023-12-07 04:47:00.0 +01:00
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  +root: App\Entity\EntryComment {#4157}
  +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
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      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
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                  +body: """
                    > **Apigenin (herbal supplement)**\n
                    \n
                    Insomnia, anxiety\n
                    \n
                    Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                    """
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                +body: "Was curious about this since Andrew Huberman mentioned it"
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              +root: App\Entity\EntryComment {#4157}
              +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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              -id: 205119
              -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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              +editedAt: null
              +createdAt: DateTimeImmutable @1701919507 {#4605
                date: 2023-12-07 04:25:07.0 +01:00
              }
            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Thanks! Is it expensive? How much do you get?"
            +lang: "en"
            +isAdult: false
            +favouriteCount: 2
            +score: 0
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              date: 2023-12-07 04:26:04.0 +01:00
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
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              date: 2023-12-22 23:55:09.0 +01:00
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              date: 2023-12-07 04:26:04.0 +01:00
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
            \n
            I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
            """
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          -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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            date: 2023-12-07 04:43:04.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Is that the dose, 1/night before bed?"
        +lang: "en"
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          date: 2023-12-07 04:45:44.0 +01:00
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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        date: 2023-12-07 04:47:00.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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      date: 2023-12-07 04:48:49.0 +01:00
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
    \n
    I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
    \n
    The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
    \n
    Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
    """
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}
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Show voter details
47 DENIED edit
App\Entity\EntryComment {#4837
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        ---\n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
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                  +image: null
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                  +body: """
                    > **Apigenin (herbal supplement)**\n
                    \n
                    Insomnia, anxiety\n
                    \n
                    Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                    """
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                    date: 2023-12-07 04:15:02.0 +01:00
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                }
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                +body: "Was curious about this since Andrew Huberman mentioned it"
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                  date: 2023-12-07 04:22:46.0 +01:00
                }
              }
              +root: App\Entity\EntryComment {#4157}
              +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
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              -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                date: 2023-12-07 04:25:07.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Thanks! Is it expensive? How much do you get?"
            +lang: "en"
            +isAdult: false
            +favouriteCount: 2
            +score: 0
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              "@Chetzemoka@startrek.website"
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              date: 2023-12-22 23:55:09.0 +01:00
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              date: 2023-12-07 04:26:04.0 +01:00
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          +body: """
            Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
            \n
            I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
            """
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            date: 2023-12-07 04:43:04.0 +01:00
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        +body: "Is that the dose, 1/night before bed?"
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      +root: App\Entity\EntryComment {#4157}
      +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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        date: 2023-12-07 04:47:00.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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  +body: """
    I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
    \n
    I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
    \n
    The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
    \n
    Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
    """
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48 DENIED moderate
App\Entity\EntryComment {#4837
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        A Fediverse community for open-ended, thought provoking questions\n
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        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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                    > **Apigenin (herbal supplement)**\n
                    \n
                    Insomnia, anxiety\n
                    \n
                    Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                    """
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                +root: App\Entity\EntryComment {#4157}
                +body: "Was curious about this since Andrew Huberman mentioned it"
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Thanks! Is it expensive? How much do you get?"
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          +root: App\Entity\EntryComment {#4157}
          +body: """
            Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
            \n
            I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
            """
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        +body: "Is that the dose, 1/night before bed?"
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      +root: App\Entity\EntryComment {#4157}
      +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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    +root: App\Entity\EntryComment {#4157}
    +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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  +body: """
    I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
    \n
    I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
    \n
    The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
    \n
    Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
    """
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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                  +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                  +magazine: App\Entity\Magazine {#265}
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                  +parent: App\Entity\EntryComment {#4157
                    +user: App\Entity\User {#4058 …}
                    +entry: App\Entity\Entry {#2400}
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                    +image: null
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                    +body: """
                      > **Apigenin (herbal supplement)**\n
                      \n
                      Insomnia, anxiety\n
                      \n
                      Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                      """
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                      date: 2023-12-23 01:53:45.0 +01:00
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                    -id: 205080
                    -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
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                      date: 2023-12-22 23:57:18.0 +01:00
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                      date: 2023-12-07 04:15:02.0 +01:00
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Was curious about this since Andrew Huberman mentioned it"
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                +root: App\Entity\EntryComment {#4157}
                +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Thanks! Is it expensive? How much do you get?"
              +lang: "en"
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                date: 2023-12-22 23:55:09.0 +01:00
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                date: 2023-12-07 04:26:04.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
              \n
              I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
              """
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              "@Chetzemoka@startrek.website"
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          +body: "Is that the dose, 1/night before bed?"
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        +root: App\Entity\EntryComment {#4157}
        +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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          date: 2023-12-07 04:47:00.0 +01:00
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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        date: 2023-12-07 04:48:49.0 +01:00
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
      \n
      I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
      \n
      The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
      \n
      Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    Thanks, I’m in talks with the right expert hehe :)\n
    \n
    More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
    """
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App\Entity\EntryComment {#4851
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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                    +body: """
                      > **Apigenin (herbal supplement)**\n
                      \n
                      Insomnia, anxiety\n
                      \n
                      Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                      """
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                  +root: App\Entity\EntryComment {#4157}
                  +body: "Was curious about this since Andrew Huberman mentioned it"
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                -id: 205119
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              +root: App\Entity\EntryComment {#4157}
              +body: "Thanks! Is it expensive? How much do you get?"
              +lang: "en"
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                date: 2023-12-22 23:55:09.0 +01:00
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                date: 2023-12-07 04:26:04.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
              \n
              I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
              """
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          +body: "Is that the dose, 1/night before bed?"
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        +root: App\Entity\EntryComment {#4157}
        +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
      \n
      I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
      \n
      The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
      \n
      Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    Thanks, I’m in talks with the right expert hehe :)\n
    \n
    More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
    """
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}
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"App\Security\Voter\EntryCommentVoter"
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"App\Security\Voter\MessageThreadVoter"
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Show voter details
52 DENIED moderate
App\Entity\EntryComment {#4851
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      +title: "asklemmy"
      +description: """
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        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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      > **Generic name (Brand/street name)**\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                      > **Apigenin (herbal supplement)**\n
                      \n
                      Insomnia, anxiety\n
                      \n
                      Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                      """
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                  +body: "Was curious about this since Andrew Huberman mentioned it"
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                +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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              +body: "Thanks! Is it expensive? How much do you get?"
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            +body: """
              Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
              \n
              I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
              """
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          +body: "Is that the dose, 1/night before bed?"
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        +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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      +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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    +body: """
      I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
      \n
      I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
      \n
      The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
      \n
      Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
      """
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  +body: """
    Thanks, I’m in talks with the right expert hehe :)\n
    \n
    More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
    """
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54 DENIED moderate
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
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        **Rules: (interactive)**\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                      +body: """
                        > **Apigenin (herbal supplement)**\n
                        \n
                        Insomnia, anxiety\n
                        \n
                        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                        """
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                    +body: "Was curious about this since Andrew Huberman mentioned it"
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                  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                +body: "Thanks! Is it expensive? How much do you get?"
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              +body: """
                Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                \n
                I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                """
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            +body: "Is that the dose, 1/night before bed?"
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          +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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        +root: App\Entity\EntryComment {#4157}
        +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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      +body: """
        I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
        \n
        I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
        \n
        The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
        \n
        Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
        """
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      Thanks, I’m in talks with the right expert hehe :)\n
      \n
      More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
      """
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      date: 2023-12-07 05:01:17.0 +01:00
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: "Hahaha, I love working with older folks. They’re my favorite patients."
  +lang: "en"
  +isAdult: false
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    date: 2023-12-07 05:05:08.0 +01:00
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}
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Show voter details
55 DENIED edit
App\Entity\EntryComment {#4882
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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    +body: """
      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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              +parent: App\Entity\EntryComment {#4674
                +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                +magazine: App\Entity\Magazine {#265}
                +image: null
                +parent: App\Entity\EntryComment {#4606
                  +user: App\Entity\User {#4058 …}
                  +entry: App\Entity\Entry {#2400}
                  +magazine: App\Entity\Magazine {#265}
                  +image: null
                  +parent: App\Entity\EntryComment {#4506
                    +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                    +magazine: App\Entity\Magazine {#265}
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                    +parent: App\Entity\EntryComment {#4157
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                      +body: """
                        > **Apigenin (herbal supplement)**\n
                        \n
                        Insomnia, anxiety\n
                        \n
                        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                        """
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                        date: 2023-12-07 04:15:02.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Was curious about this since Andrew Huberman mentioned it"
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                      "@Chetzemoka@startrek.website"
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                      date: 2023-12-07 04:22:46.0 +01:00
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                    date: 2023-12-07 04:25:07.0 +01:00
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
                  ]
                  +children: Doctrine\ORM\PersistentCollection {#4607 …}
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                  -id: 205119
                  -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                    date: 2023-12-07 04:25:07.0 +01:00
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Thanks! Is it expensive? How much do you get?"
                +lang: "en"
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                  "@Chetzemoka@startrek.website"
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                -bodyTs: "'expens':4 'get':9 'much':6 'thank':1"
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: """
                Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                \n
                I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                """
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              -id: 205159
              -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                date: 2023-12-07 04:43:04.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Is that the dose, 1/night before bed?"
            +lang: "en"
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              date: 2023-12-07 04:45:44.0 +01:00
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          +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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        +root: App\Entity\EntryComment {#4157}
        +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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          date: 2023-12-07 04:48:49.0 +01:00
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      +body: """
        I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
        \n
        I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
        \n
        The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
        \n
        Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
        """
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    +body: """
      Thanks, I’m in talks with the right expert hehe :)\n
      \n
      More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
      """
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  +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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                      +body: """
                        > **Apigenin (herbal supplement)**\n
                        \n
                        Insomnia, anxiety\n
                        \n
                        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                        """
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                    +body: "Was curious about this since Andrew Huberman mentioned it"
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                  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                  -id: 205119
                  -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
                  +ranking: 0
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                  +editedAt: null
                  +createdAt: DateTimeImmutable @1701919507 {#4605
                    date: 2023-12-07 04:25:07.0 +01:00
                  }
                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Thanks! Is it expensive? How much do you get?"
                +lang: "en"
                +isAdult: false
                +favouriteCount: 2
                +score: 0
                +lastActive: DateTime @1701919564 {#4671
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                  "@cheese_greater@lemmy.world"
                  "@Chetzemoka@startrek.website"
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                +apId: "https://lemmy.world/comment/5862429"
                +editedAt: DateTimeImmutable @1703285709 {#4672
                  date: 2023-12-22 23:55:09.0 +01:00
                }
                +createdAt: DateTimeImmutable @1701919564 {#4673
                  date: 2023-12-07 04:26:04.0 +01:00
                }
              }
              +root: App\Entity\EntryComment {#4157}
              +body: """
                Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                \n
                I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                """
              +lang: "en"
              +isAdult: false
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                date: 2023-12-07 04:43:04.0 +01:00
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
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              -id: 205159
              -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                date: 2023-12-07 04:43:04.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Is that the dose, 1/night before bed?"
            +lang: "en"
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              "@Chetzemoka@startrek.website"
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              date: 2023-12-07 04:45:44.0 +01:00
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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            "@Chetzemoka@startrek.website"
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            date: 2023-12-07 04:47:00.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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          date: 2023-12-07 04:48:49.0 +01:00
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      +root: App\Entity\EntryComment {#4157}
      +body: """
        I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
        \n
        I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
        \n
        The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
        \n
        Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
        """
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      Thanks, I’m in talks with the right expert hehe :)\n
      \n
      More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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                  +magazine: App\Entity\Magazine {#265}
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                    +user: App\Entity\User {#4058 …}
                    +entry: App\Entity\Entry {#2400}
                    +magazine: App\Entity\Magazine {#265}
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                    +parent: App\Entity\EntryComment {#4506
                      +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                      +parent: App\Entity\EntryComment {#4157
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                        +entry: App\Entity\Entry {#2400}
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                        +image: null
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                        +root: null
                        +body: """
                          > **Apigenin (herbal supplement)**\n
                          \n
                          Insomnia, anxiety\n
                          \n
                          Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                          """
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                          date: 2023-12-22 23:57:18.0 +01:00
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                          date: 2023-12-07 04:15:02.0 +01:00
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                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Was curious about this since Andrew Huberman mentioned it"
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                        date: 2023-12-07 04:22:46.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                      "@Chetzemoka@startrek.website"
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                    -id: 205119
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                      date: 2023-12-07 04:25:07.0 +01:00
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Thanks! Is it expensive? How much do you get?"
                  +lang: "en"
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                    "@Chetzemoka@startrek.website"
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                    date: 2023-12-22 23:55:09.0 +01:00
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                    date: 2023-12-07 04:26:04.0 +01:00
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: """
                  Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                  \n
                  I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                  """
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                  date: 2023-12-07 04:43:04.0 +01:00
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                  "@Chetzemoka@startrek.website"
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                -id: 205159
                -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                  date: 2023-12-07 04:43:04.0 +01:00
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Is that the dose, 1/night before bed?"
              +lang: "en"
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                date: 2023-12-07 04:45:44.0 +01:00
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              -id: 205164
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                date: 2023-12-07 04:45:44.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
            +lang: "en"
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              date: 2023-12-07 04:47:00.0 +01:00
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            -id: 205166
            -bodyTs: "'200mg':8 'bedtim':13 'dose':7 'hour':11 'like':9 'recommend':6 'usual':5 'yep':1"
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              date: 2023-12-07 04:47:00.0 +01:00
            }
          }
          +root: App\Entity\EntryComment {#4157}
          +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
          +lang: "en"
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            date: 2023-12-07 04:48:49.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: """
          I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
          \n
          I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
          \n
          The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
          \n
          Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
          """
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        +isAdult: false
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          date: 2023-12-07 04:59:05.0 +01:00
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: """
        Thanks, I’m in talks with the right expert hehe :)\n
        \n
        More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
        """
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        date: 2023-12-23 00:18:32.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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      date: 2023-12-07 05:05:08.0 +01:00
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: "Re:Apigenin -> sleep quality?"
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    date: 2023-12-23 00:21:11.0 +01:00
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}
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Show voter details
59 DENIED edit
App\Entity\EntryComment {#4896
  +user: Proxies\__CG__\App\Entity\User {#1978 …}
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    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                        +body: """
                          > **Apigenin (herbal supplement)**\n
                          \n
                          Insomnia, anxiety\n
                          \n
                          Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                          """
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                      +body: "Was curious about this since Andrew Huberman mentioned it"
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                    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                  +body: "Thanks! Is it expensive? How much do you get?"
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                +body: """
                  Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                  \n
                  I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                  """
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              +body: "Is that the dose, 1/night before bed?"
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            +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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          +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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        +body: """
          I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
          \n
          I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
          \n
          The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
          \n
          Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
          """
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      +body: """
        Thanks, I’m in talks with the right expert hehe :)\n
        \n
        More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
        """
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    +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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  +body: "Re:Apigenin -> sleep quality?"
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60 DENIED moderate
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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                        +body: """
                          > **Apigenin (herbal supplement)**\n
                          \n
                          Insomnia, anxiety\n
                          \n
                          Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                          """
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                      +body: "Was curious about this since Andrew Huberman mentioned it"
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                    +root: App\Entity\EntryComment {#4157}
                    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                    -id: 205119
                    -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                  +body: "Thanks! Is it expensive? How much do you get?"
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                +body: """
                  Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                  \n
                  I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                  """
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              +root: App\Entity\EntryComment {#4157}
              +body: "Is that the dose, 1/night before bed?"
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            +root: App\Entity\EntryComment {#4157}
            +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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          +root: App\Entity\EntryComment {#4157}
          +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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        +body: """
          I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
          \n
          I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
          \n
          The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
          \n
          Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
          """
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      +body: """
        Thanks, I’m in talks with the right expert hehe :)\n
        \n
        More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
        """
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    +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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  +body: "Re:Apigenin -> sleep quality?"
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                          +body: """
                            > **Apigenin (herbal supplement)**\n
                            \n
                            Insomnia, anxiety\n
                            \n
                            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                            """
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                        +body: "Was curious about this since Andrew Huberman mentioned it"
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                      +root: App\Entity\EntryComment {#4157}
                      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                      -id: 205119
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Thanks! Is it expensive? How much do you get?"
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                      date: 2023-12-07 04:26:04.0 +01:00
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: """
                    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                    \n
                    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                    """
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                +body: "Is that the dose, 1/night before bed?"
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              +root: App\Entity\EntryComment {#4157}
              +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                date: 2023-12-07 04:47:00.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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              date: 2023-12-07 04:48:49.0 +01:00
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          +body: """
            I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
            \n
            I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
            \n
            The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
            \n
            Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
            """
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        +body: """
          Thanks, I’m in talks with the right expert hehe :)\n
          \n
          More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
          """
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      +root: App\Entity\EntryComment {#4157}
      +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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    +root: App\Entity\EntryComment {#4157}
    +body: "Re:Apigenin -> sleep quality?"
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  +root: App\Entity\EntryComment {#4157}
  +body: "Literally the only thing that gives me refreshing sleep. (See also: mitochondrial dysfunction that I mentioned in my other comment about CQ10.) Apigenin seems to improve what’s called “sleep architecture” in a way that none of the pharmaceuticals I’ve ever tried do."
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App\Entity\EntryComment {#4927
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        A Fediverse community for open-ended, thought provoking questions\n
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        **Rules: (interactive)**\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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                          +body: """
                            > **Apigenin (herbal supplement)**\n
                            \n
                            Insomnia, anxiety\n
                            \n
                            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                            """
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                        +body: "Was curious about this since Andrew Huberman mentioned it"
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                      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                    +body: "Thanks! Is it expensive? How much do you get?"
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                  +body: """
                    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                    \n
                    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                    """
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                +body: "Is that the dose, 1/night before bed?"
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              +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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            +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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          +body: """
            I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
            \n
            I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
            \n
            The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
            \n
            Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
            """
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        +body: """
          Thanks, I’m in talks with the right expert hehe :)\n
          \n
          More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
          """
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      +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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    +body: "Re:Apigenin -> sleep quality?"
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  +root: App\Entity\EntryComment {#4157}
  +body: "Literally the only thing that gives me refreshing sleep. (See also: mitochondrial dysfunction that I mentioned in my other comment about CQ10.) Apigenin seems to improve what’s called “sleep architecture” in a way that none of the pharmaceuticals I’ve ever tried do."
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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                          +magazine: App\Entity\Magazine {#265}
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                          +body: """
                            > **Apigenin (herbal supplement)**\n
                            \n
                            Insomnia, anxiety\n
                            \n
                            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                            """
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                        +body: "Was curious about this since Andrew Huberman mentioned it"
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                      +root: App\Entity\EntryComment {#4157}
                      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                    +body: "Thanks! Is it expensive? How much do you get?"
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                  +body: """
                    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                    \n
                    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                    """
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                +body: "Is that the dose, 1/night before bed?"
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              +root: App\Entity\EntryComment {#4157}
              +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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            +root: App\Entity\EntryComment {#4157}
            +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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          +body: """
            I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
            \n
            I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
            \n
            The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
            \n
            Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
            """
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        +body: """
          Thanks, I’m in talks with the right expert hehe :)\n
          \n
          More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
          """
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      +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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    +body: "Re:Apigenin -> sleep quality?"
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  +body: "Literally the only thing that gives me refreshing sleep. (See also: mitochondrial dysfunction that I mentioned in my other comment about CQ10.) Apigenin seems to improve what’s called “sleep architecture” in a way that none of the pharmaceuticals I’ve ever tried do."
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                            +magazine: App\Entity\Magazine {#265}
                            +image: null
                            +parent: null
                            +root: null
                            +body: """
                              > **Apigenin (herbal supplement)**\n
                              \n
                              Insomnia, anxiety\n
                              \n
                              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                              """
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                              date: 2023-12-23 01:53:45.0 +01:00
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                            +tags: null
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                              "@cheese_greater@lemmy.world"
                            ]
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                            -id: 205080
                            -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
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                            +editedAt: DateTimeImmutable @1703285838 {#4152
                              date: 2023-12-22 23:57:18.0 +01:00
                            }
                            +createdAt: DateTimeImmutable @1701918902 {#4153
                              date: 2023-12-07 04:15:02.0 +01:00
                            }
                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Was curious about this since Andrew Huberman mentioned it"
                          +lang: "en"
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                            "@Chetzemoka@startrek.website"
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                            date: 2023-12-07 04:22:46.0 +01:00
                          }
                        }
                        +root: App\Entity\EntryComment {#4157}
                        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                          "@Chetzemoka@startrek.website"
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                          date: 2023-12-07 04:25:07.0 +01:00
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                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Thanks! Is it expensive? How much do you get?"
                      +lang: "en"
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                        date: 2023-12-22 23:55:09.0 +01:00
                      }
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                        date: 2023-12-07 04:26:04.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: """
                      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                      \n
                      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                      """
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                      date: 2023-12-07 04:43:04.0 +01:00
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                      "@Chetzemoka@startrek.website"
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                      date: 2023-12-07 04:43:04.0 +01:00
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Is that the dose, 1/night before bed?"
                  +lang: "en"
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                    date: 2023-12-07 04:45:44.0 +01:00
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
                +lang: "en"
                +isAdult: false
                +favouriteCount: 2
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                  date: 2023-12-07 04:47:00.0 +01:00
                }
              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
              +lang: "en"
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              +ranking: 0
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              +apId: "https://lemmy.world/comment/5862796"
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                date: 2023-12-07 04:48:49.0 +01:00
              }
            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
              \n
              I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
              \n
              The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
              \n
              Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
              """
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            +isAdult: false
            +favouriteCount: 1
            +score: 0
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              "@Chetzemoka@startrek.website"
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              date: 2023-12-07 04:59:05.0 +01:00
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            Thanks, I’m in talks with the right expert hehe :)\n
            \n
            More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
            """
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            "@Chetzemoka@startrek.website"
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            date: 2023-12-23 00:18:32.0 +01:00
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            date: 2023-12-07 05:01:17.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Hahaha, I love working with older folks. They’re my favorite patients."
        +lang: "en"
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: "Re:Apigenin -> sleep quality?"
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        date: 2023-12-23 00:21:11.0 +01:00
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        date: 2023-12-07 05:06:34.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Literally the only thing that gives me refreshing sleep. (See also: mitochondrial dysfunction that I mentioned in my other comment about CQ10.) Apigenin seems to improve what’s called “sleep architecture” in a way that none of the pharmaceuticals I’ve ever tried do."
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    -id: 205217
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: "Shit, I may have to try it first. Im getting other sleep stuff done but every bit helps"
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}
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"App\Security\Voter\EntryCommentVoter"
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Show voter details
67 DENIED edit
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                            +body: """
                              > **Apigenin (herbal supplement)**\n
                              \n
                              Insomnia, anxiety\n
                              \n
                              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                              """
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                          +body: "Was curious about this since Andrew Huberman mentioned it"
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                        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                      +body: "Thanks! Is it expensive? How much do you get?"
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                    +body: """
                      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                      \n
                      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                      """
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                  +body: "Is that the dose, 1/night before bed?"
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                +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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              +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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            +body: """
              I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
              \n
              I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
              \n
              The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
              \n
              Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
              """
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          +body: """
            Thanks, I’m in talks with the right expert hehe :)\n
            \n
            More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
            """
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        +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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      +body: "Re:Apigenin -> sleep quality?"
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    +body: "Literally the only thing that gives me refreshing sleep. (See also: mitochondrial dysfunction that I mentioned in my other comment about CQ10.) Apigenin seems to improve what’s called “sleep architecture” in a way that none of the pharmaceuticals I’ve ever tried do."
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  +body: "Shit, I may have to try it first. Im getting other sleep stuff done but every bit helps"
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                            +body: """
                              > **Apigenin (herbal supplement)**\n
                              \n
                              Insomnia, anxiety\n
                              \n
                              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                              """
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                          +body: "Was curious about this since Andrew Huberman mentioned it"
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                        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                          "@Chetzemoka@startrek.website"
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                          date: 2023-12-07 04:25:07.0 +01:00
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                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Thanks! Is it expensive? How much do you get?"
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                        date: 2023-12-22 23:55:09.0 +01:00
                      }
                      +createdAt: DateTimeImmutable @1701919564 {#4673
                        date: 2023-12-07 04:26:04.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: """
                      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                      \n
                      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                      """
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                      date: 2023-12-07 04:43:04.0 +01:00
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                      "@Chetzemoka@startrek.website"
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                    -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                      date: 2023-12-07 04:43:04.0 +01:00
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Is that the dose, 1/night before bed?"
                  +lang: "en"
                  +isAdult: false
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                    "@Chetzemoka@startrek.website"
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                    date: 2023-12-07 04:45:44.0 +01:00
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
                +lang: "en"
                +isAdult: false
                +favouriteCount: 2
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                  "@Chetzemoka@startrek.website"
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                -id: 205166
                -bodyTs: "'200mg':8 'bedtim':13 'dose':7 'hour':11 'like':9 'recommend':6 'usual':5 'yep':1"
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                +createdAt: DateTimeImmutable @1701920820 {#4781
                  date: 2023-12-07 04:47:00.0 +01:00
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
              +lang: "en"
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
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                date: 2023-12-07 04:48:49.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
              \n
              I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
              \n
              The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
              \n
              Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
              """
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            +isAdult: false
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              "@Chetzemoka@startrek.website"
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              date: 2023-12-07 04:59:05.0 +01:00
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            Thanks, I’m in talks with the right expert hehe :)\n
            \n
            More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
            """
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            "@Chetzemoka@startrek.website"
          ]
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            date: 2023-12-23 00:18:32.0 +01:00
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            date: 2023-12-07 05:01:17.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Hahaha, I love working with older folks. They’re my favorite patients."
        +lang: "en"
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          date: 2023-12-07 05:05:08.0 +01:00
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: "Re:Apigenin -> sleep quality?"
      +lang: "en"
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        date: 2023-12-07 05:06:34.0 +01:00
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        "@Chetzemoka@startrek.website"
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      -bodyTs: "'apigenin':2 'qualiti':4 're':1 'sleep':3"
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        date: 2023-12-23 00:21:11.0 +01:00
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        date: 2023-12-07 05:06:34.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Literally the only thing that gives me refreshing sleep. (See also: mitochondrial dysfunction that I mentioned in my other comment about CQ10.) Apigenin seems to improve what’s called “sleep architecture” in a way that none of the pharmaceuticals I’ve ever tried do."
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      "@Chetzemoka@startrek.website"
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    -id: 205217
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: "Shit, I may have to try it first. Im getting other sleep stuff done but every bit helps"
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}
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App\Entity\EntryComment {#4936
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      +title: "asklemmy"
      +description: """
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        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        ---\n
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      > **Generic name (Brand/street name)**\n
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      Discussion paragraphs/submission\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                          +body: """
                            > **Apigenin (herbal supplement)**\n
                            \n
                            Insomnia, anxiety\n
                            \n
                            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                            """
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                        +body: "Was curious about this since Andrew Huberman mentioned it"
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                      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                    +body: "Thanks! Is it expensive? How much do you get?"
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                  +body: """
                    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                    \n
                    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                    """
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                +body: "Is that the dose, 1/night before bed?"
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              +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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            +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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          +body: """
            I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
            \n
            I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
            \n
            The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
            \n
            Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
            """
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        +body: """
          Thanks, I’m in talks with the right expert hehe :)\n
          \n
          More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
          """
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        +editedAt: DateTimeImmutable @1703287112 {#4857
          date: 2023-12-23 00:18:32.0 +01:00
        }
        +createdAt: DateTimeImmutable @1701921677 {#4859
          date: 2023-12-07 05:01:17.0 +01:00
        }
      }
      +root: App\Entity\EntryComment {#4157}
      +body: "Hahaha, I love working with older folks. They’re my favorite patients."
      +lang: "en"
      +isAdult: false
      +favouriteCount: 1
      +score: 0
      +lastActive: DateTime @1701921908 {#4877
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        "@cheese_greater@lemmy.world"
        "@Chetzemoka@startrek.website"
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        date: 2023-12-07 05:05:08.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Re:Apigenin -> sleep quality?"
    +lang: "en"
    +isAdult: false
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      "@cheese_greater@lemmy.world"
      "@Chetzemoka@startrek.website"
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    -id: 205201
    -bodyTs: "'apigenin':2 'qualiti':4 're':1 'sleep':3"
    +ranking: 0
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      date: 2023-12-23 00:21:11.0 +01:00
    }
    +createdAt: DateTimeImmutable @1701921994 {#4904
      date: 2023-12-07 05:06:34.0 +01:00
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: """
    Here, I found a good article for you:\n
    \n
    [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
    """
  +lang: "en"
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    date: 2023-12-07 05:16:15.0 +01:00
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    "@cheese_greater@lemmy.world"
    "@Chetzemoka@startrek.website"
  ]
  +children: Doctrine\ORM\PersistentCollection {#4937 …}
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  -id: 205227
  -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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    date: 2023-12-07 05:16:15.0 +01:00
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}
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71 DENIED edit
App\Entity\EntryComment {#4936
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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                +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                +magazine: App\Entity\Magazine {#265}
                +image: null
                +parent: App\Entity\EntryComment {#4728
                  +user: App\Entity\User {#4058 …}
                  +entry: App\Entity\Entry {#2400}
                  +magazine: App\Entity\Magazine {#265}
                  +image: null
                  +parent: App\Entity\EntryComment {#4674
                    +user: Proxies\__CG__\App\Entity\User {#1978 …}
                    +entry: App\Entity\Entry {#2400}
                    +magazine: App\Entity\Magazine {#265}
                    +image: null
                    +parent: App\Entity\EntryComment {#4606
                      +user: App\Entity\User {#4058 …}
                      +entry: App\Entity\Entry {#2400}
                      +magazine: App\Entity\Magazine {#265}
                      +image: null
                      +parent: App\Entity\EntryComment {#4506
                        +user: Proxies\__CG__\App\Entity\User {#1978 …}
                        +entry: App\Entity\Entry {#2400}
                        +magazine: App\Entity\Magazine {#265}
                        +image: null
                        +parent: App\Entity\EntryComment {#4157
                          +user: App\Entity\User {#4058 …}
                          +entry: App\Entity\Entry {#2400}
                          +magazine: App\Entity\Magazine {#265}
                          +image: null
                          +parent: null
                          +root: null
                          +body: """
                            > **Apigenin (herbal supplement)**\n
                            \n
                            Insomnia, anxiety\n
                            \n
                            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                            """
                          +lang: "en"
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                            date: 2023-12-23 01:53:45.0 +01:00
                          }
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                          +tags: null
                          +mentions: [
                            "@cheese_greater@lemmy.world"
                          ]
                          +children: Doctrine\ORM\PersistentCollection {#4158 …}
                          +nested: Doctrine\ORM\PersistentCollection {#4160 …}
                          +votes: Doctrine\ORM\PersistentCollection {#4162 …}
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                          +favourites: Doctrine\ORM\PersistentCollection {#4166 …}
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                          -id: 205080
                          -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
                          +ranking: 0
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                          +apId: "https://startrek.website/comment/4793481"
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                            date: 2023-12-22 23:57:18.0 +01:00
                          }
                          +createdAt: DateTimeImmutable @1701918902 {#4153
                            date: 2023-12-07 04:15:02.0 +01:00
                          }
                        }
                        +root: App\Entity\EntryComment {#4157}
                        +body: "Was curious about this since Andrew Huberman mentioned it"
                        +lang: "en"
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                          date: 2023-12-07 04:22:46.0 +01:00
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                          "@cheese_greater@lemmy.world"
                          "@Chetzemoka@startrek.website"
                        ]
                        +children: Doctrine\ORM\PersistentCollection {#4507 …}
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                        -id: 205105
                        -bodyTs: "'andrew':6 'curious':2 'huberman':7 'mention':8 'sinc':5"
                        +ranking: 0
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                        +createdAt: DateTimeImmutable @1701919366 {#4505
                          date: 2023-12-07 04:22:46.0 +01:00
                        }
                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
                      +lang: "en"
                      +isAdult: false
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                        date: 2023-12-07 04:25:07.0 +01:00
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
                      ]
                      +children: Doctrine\ORM\PersistentCollection {#4607 …}
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                      -id: 205119
                      -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                        date: 2023-12-07 04:25:07.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Thanks! Is it expensive? How much do you get?"
                    +lang: "en"
                    +isAdult: false
                    +favouriteCount: 2
                    +score: 0
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                      date: 2023-12-07 04:26:04.0 +01:00
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                      "@cheese_greater@lemmy.world"
                      "@Chetzemoka@startrek.website"
                    ]
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                    -id: 205122
                    -bodyTs: "'expens':4 'get':9 'much':6 'thank':1"
                    +ranking: 0
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                    +visibility: "visible             "
                    +apId: "https://lemmy.world/comment/5862429"
                    +editedAt: DateTimeImmutable @1703285709 {#4672
                      date: 2023-12-22 23:55:09.0 +01:00
                    }
                    +createdAt: DateTimeImmutable @1701919564 {#4673
                      date: 2023-12-07 04:26:04.0 +01:00
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: """
                    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                    \n
                    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                    """
                  +lang: "en"
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
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                  -id: 205159
                  -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                    date: 2023-12-07 04:43:04.0 +01:00
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Is that the dose, 1/night before bed?"
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                  "@Chetzemoka@startrek.website"
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              +root: App\Entity\EntryComment {#4157}
              +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                date: 2023-12-07 04:47:00.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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          +body: """
            I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
            \n
            I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
            \n
            The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
            \n
            Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
            """
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        +body: """
          Thanks, I’m in talks with the right expert hehe :)\n
          \n
          More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
          """
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      +root: App\Entity\EntryComment {#4157}
      +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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    +root: App\Entity\EntryComment {#4157}
    +body: "Re:Apigenin -> sleep quality?"
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    Here, I found a good article for you:\n
    \n
    [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
    """
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                          +entry: App\Entity\Entry {#2400}
                          +magazine: App\Entity\Magazine {#265}
                          +image: null
                          +parent: null
                          +root: null
                          +body: """
                            > **Apigenin (herbal supplement)**\n
                            \n
                            Insomnia, anxiety\n
                            \n
                            Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                            """
                          +lang: "en"
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                          +lastActive: DateTime @1703292825 {#4151
                            date: 2023-12-23 01:53:45.0 +01:00
                          }
                          +ip: null
                          +tags: null
                          +mentions: [
                            "@cheese_greater@lemmy.world"
                          ]
                          +children: Doctrine\ORM\PersistentCollection {#4158 …}
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                          -id: 205080
                          -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
                          +ranking: 0
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                          +visibility: "visible             "
                          +apId: "https://startrek.website/comment/4793481"
                          +editedAt: DateTimeImmutable @1703285838 {#4152
                            date: 2023-12-22 23:57:18.0 +01:00
                          }
                          +createdAt: DateTimeImmutable @1701918902 {#4153
                            date: 2023-12-07 04:15:02.0 +01:00
                          }
                        }
                        +root: App\Entity\EntryComment {#4157}
                        +body: "Was curious about this since Andrew Huberman mentioned it"
                        +lang: "en"
                        +isAdult: false
                        +favouriteCount: 1
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                        +lastActive: DateTime @1701919366 {#4504
                          date: 2023-12-07 04:22:46.0 +01:00
                        }
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                          "@cheese_greater@lemmy.world"
                          "@Chetzemoka@startrek.website"
                        ]
                        +children: Doctrine\ORM\PersistentCollection {#4507 …}
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                        -id: 205105
                        -bodyTs: "'andrew':6 'curious':2 'huberman':7 'mention':8 'sinc':5"
                        +ranking: 0
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                        +apId: "https://lemmy.world/comment/5862359"
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                        +createdAt: DateTimeImmutable @1701919366 {#4505
                          date: 2023-12-07 04:22:46.0 +01:00
                        }
                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
                      +lang: "en"
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                        date: 2023-12-07 04:25:07.0 +01:00
                      }
                      +ip: null
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
                      ]
                      +children: Doctrine\ORM\PersistentCollection {#4607 …}
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                      -id: 205119
                      -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
                      +ranking: 0
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                      +createdAt: DateTimeImmutable @1701919507 {#4605
                        date: 2023-12-07 04:25:07.0 +01:00
                      }
                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Thanks! Is it expensive? How much do you get?"
                    +lang: "en"
                    +isAdult: false
                    +favouriteCount: 2
                    +score: 0
                    +lastActive: DateTime @1701919564 {#4671
                      date: 2023-12-07 04:26:04.0 +01:00
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                      "@cheese_greater@lemmy.world"
                      "@Chetzemoka@startrek.website"
                    ]
                    +children: Doctrine\ORM\PersistentCollection {#4675 …}
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                    -id: 205122
                    -bodyTs: "'expens':4 'get':9 'much':6 'thank':1"
                    +ranking: 0
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                    +apId: "https://lemmy.world/comment/5862429"
                    +editedAt: DateTimeImmutable @1703285709 {#4672
                      date: 2023-12-22 23:55:09.0 +01:00
                    }
                    +createdAt: DateTimeImmutable @1701919564 {#4673
                      date: 2023-12-07 04:26:04.0 +01:00
                    }
                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: """
                    Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                    \n
                    I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                    """
                  +lang: "en"
                  +isAdult: false
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                  +score: 0
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                    date: 2023-12-07 04:43:04.0 +01:00
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
                  ]
                  +children: Doctrine\ORM\PersistentCollection {#4729 …}
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                  -id: 205159
                  -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
                  +ranking: 0
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                    date: 2023-12-07 04:43:04.0 +01:00
                  }
                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Is that the dose, 1/night before bed?"
                +lang: "en"
                +isAdult: false
                +favouriteCount: 2
                +score: 0
                +lastActive: DateTime @1701920744 {#4763
                  date: 2023-12-07 04:45:44.0 +01:00
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                  "@cheese_greater@lemmy.world"
                  "@Chetzemoka@startrek.website"
                ]
                +children: Doctrine\ORM\PersistentCollection {#4766 …}
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                -id: 205164
                -bodyTs: "'1/night':5 'bed':7 'dose':4"
                +ranking: 0
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                +apId: "https://lemmy.world/comment/5862753"
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                  date: 2023-12-07 04:45:44.0 +01:00
                }
              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
              +lang: "en"
              +isAdult: false
              +favouriteCount: 2
              +score: 0
              +lastActive: DateTime @1701920820 {#4784
                date: 2023-12-07 04:47:00.0 +01:00
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
              ]
              +children: Doctrine\ORM\PersistentCollection {#4787 …}
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              -id: 205166
              -bodyTs: "'200mg':8 'bedtim':13 'dose':7 'hour':11 'like':9 'recommend':6 'usual':5 'yep':1"
              +ranking: 0
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              +createdAt: DateTimeImmutable @1701920820 {#4781
                date: 2023-12-07 04:47:00.0 +01:00
              }
            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
            +lang: "en"
            +isAdult: false
            +favouriteCount: 2
            +score: 0
            +lastActive: DateTime @1701920929 {#4810
              date: 2023-12-07 04:48:49.0 +01:00
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
            ]
            +children: Doctrine\ORM\PersistentCollection {#4807 …}
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            -id: 205169
            -bodyTs: "'calm':18 'citrat':28 'd':44 'easier':36 'effect':25 'except':21 'extent':42 'gi':24 'grandmoth':10 'like':12,14,17 'magnesium':19,27 'might':11,34 'particular':8 'recommend':3 'senior':7 'sleep':20 'someth':13 'system':39 'wonder':31 'would':1"
            +ranking: 0
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            +apId: "https://lemmy.world/comment/5862796"
            +editedAt: null
            +createdAt: DateTimeImmutable @1701920929 {#4813
              date: 2023-12-07 04:48:49.0 +01:00
            }
          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
            \n
            I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
            \n
            The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
            \n
            Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
            """
          +lang: "en"
          +isAdult: false
          +favouriteCount: 1
          +score: 0
          +lastActive: DateTime @1701921545 {#4832
            date: 2023-12-07 04:59:05.0 +01:00
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
          ]
          +children: Doctrine\ORM\PersistentCollection {#4829 …}
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          -id: 205188
          -bodyTs: "'actual':2 'add':74 'anticholinerg':13 'anymor':128 'blood':32 'bodi':117 'build':113 'call':99 'cardiac':35,141 'caus':110 'cautious':106 'caveat':71 'citrat':60 'common':31 'could':63 'coumadin':101 'definit':78 'doctor':81 'doesn':25 'drug':98 'effect':15,57 'even':107 'folk':39,147 'glycin':51 'help':137 'hope':135 'interact':27 'laxat':56 'less':53 'like':16 'lot':18,149 'm':139 'mag':50,59 'magnesium':48 'med':36 'much':127 'nurs':142 'often':40 'older':38,146 'otc':89 'pharmaceut':20 'pressur':33 'problem':46 'recommend':4 'sedat':21 'senior':7 'side':14 'specif':95 'suck':119 'supplement':49,90 'take':41,84 'tell':79 'tri':64 'two':70 'tylenol':108 'unheard':133 'use':124 'warfarin':100,111,118 'well':67 'work':144 'would':3,73"
          +ranking: 0
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            date: 2023-12-07 04:59:05.0 +01:00
          }
        }
        +root: App\Entity\EntryComment {#4157}
        +body: """
          Thanks, I’m in talks with the right expert hehe :)\n
          \n
          More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
          """
        +lang: "en"
        +isAdult: false
        +favouriteCount: 2
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          "@cheese_greater@lemmy.world"
          "@Chetzemoka@startrek.website"
        ]
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        -id: 205195
        -bodyTs: "'construct':25 'end':28 'expert':9 'genuin':15 'hehe':10 'help':16 'm':3 'qualiti':18 'right':8 'sleep':20 'specif':12 'talk':5 'thank':1 'thing':23 'toward':26 'turn':30"
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        +editedAt: DateTimeImmutable @1703287112 {#4857
          date: 2023-12-23 00:18:32.0 +01:00
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        +createdAt: DateTimeImmutable @1701921677 {#4859
          date: 2023-12-07 05:01:17.0 +01:00
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: "Hahaha, I love working with older folks. They’re my favorite patients."
      +lang: "en"
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        "@cheese_greater@lemmy.world"
        "@Chetzemoka@startrek.website"
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        date: 2023-12-07 05:05:08.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: "Re:Apigenin -> sleep quality?"
    +lang: "en"
    +isAdult: false
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    +score: 0
    +lastActive: DateTime @1701921994 {#4899
      date: 2023-12-07 05:06:34.0 +01:00
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      "@cheese_greater@lemmy.world"
      "@Chetzemoka@startrek.website"
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    -id: 205201
    -bodyTs: "'apigenin':2 'qualiti':4 're':1 'sleep':3"
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    +visibility: "visible             "
    +apId: "https://lemmy.world/comment/5863034"
    +editedAt: DateTimeImmutable @1703287271 {#4902
      date: 2023-12-23 00:21:11.0 +01:00
    }
    +createdAt: DateTimeImmutable @1701921994 {#4904
      date: 2023-12-07 05:06:34.0 +01:00
    }
  }
  +root: App\Entity\EntryComment {#4157}
  +body: """
    Here, I found a good article for you:\n
    \n
    [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
    """
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    "@cheese_greater@lemmy.world"
    "@Chetzemoka@startrek.website"
  ]
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  -id: 205227
  -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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}
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App\Entity\EntryComment {#4973
  +user: Proxies\__CG__\App\Entity\User {#1978 …}
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    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                            +body: """
                              > **Apigenin (herbal supplement)**\n
                              \n
                              Insomnia, anxiety\n
                              \n
                              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                              """
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                          +body: "Was curious about this since Andrew Huberman mentioned it"
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                        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                      +body: "Thanks! Is it expensive? How much do you get?"
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                    +body: """
                      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                      \n
                      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                      """
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                  +body: "Is that the dose, 1/night before bed?"
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                +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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              +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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            +body: """
              I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
              \n
              I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
              \n
              The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
              \n
              Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
              """
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          +root: App\Entity\EntryComment {#4157}
          +body: """
            Thanks, I’m in talks with the right expert hehe :)\n
            \n
            More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
            """
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            "@Chetzemoka@startrek.website"
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        +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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      +body: "Re:Apigenin -> sleep quality?"
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        date: 2023-12-07 05:06:34.0 +01:00
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      Here, I found a good article for you:\n
      \n
      [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
      """
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    -id: 205227
    -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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      date: 2023-12-07 05:16:15.0 +01:00
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
    \n
    Thanks and no rush, I’ll listen to that article tomorrow :)
    """
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                            +body: """
                              > **Apigenin (herbal supplement)**\n
                              \n
                              Insomnia, anxiety\n
                              \n
                              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                              """
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                          +root: App\Entity\EntryComment {#4157}
                          +body: "Was curious about this since Andrew Huberman mentioned it"
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                        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
                        +lang: "en"
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                          "@Chetzemoka@startrek.website"
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                          date: 2023-12-07 04:25:07.0 +01:00
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                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Thanks! Is it expensive? How much do you get?"
                      +lang: "en"
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                        date: 2023-12-22 23:55:09.0 +01:00
                      }
                      +createdAt: DateTimeImmutable @1701919564 {#4673
                        date: 2023-12-07 04:26:04.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: """
                      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                      \n
                      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                      """
                    +lang: "en"
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                      date: 2023-12-07 04:43:04.0 +01:00
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                    -id: 205159
                    -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                      date: 2023-12-07 04:43:04.0 +01:00
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                  +root: App\Entity\EntryComment {#4157}
                  +body: "Is that the dose, 1/night before bed?"
                  +lang: "en"
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                    date: 2023-12-07 04:45:44.0 +01:00
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
                +lang: "en"
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                  date: 2023-12-07 04:47:00.0 +01:00
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
              +lang: "en"
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                date: 2023-12-07 04:48:49.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
              \n
              I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
              \n
              The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
              \n
              Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
              """
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            +isAdult: false
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              "@Chetzemoka@startrek.website"
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              date: 2023-12-07 04:59:05.0 +01:00
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          +root: App\Entity\EntryComment {#4157}
          +body: """
            Thanks, I’m in talks with the right expert hehe :)\n
            \n
            More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
            """
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
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            date: 2023-12-23 00:18:32.0 +01:00
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            date: 2023-12-07 05:01:17.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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          date: 2023-12-07 05:05:08.0 +01:00
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      +root: App\Entity\EntryComment {#4157}
      +body: "Re:Apigenin -> sleep quality?"
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        date: 2023-12-07 05:06:34.0 +01:00
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        "@Chetzemoka@startrek.website"
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      -id: 205201
      -bodyTs: "'apigenin':2 'qualiti':4 're':1 'sleep':3"
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        date: 2023-12-23 00:21:11.0 +01:00
      }
      +createdAt: DateTimeImmutable @1701921994 {#4904
        date: 2023-12-07 05:06:34.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: """
      Here, I found a good article for you:\n
      \n
      [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
      """
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      "@cheese_greater@lemmy.world"
      "@Chetzemoka@startrek.website"
    ]
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    -id: 205227
    -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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      date: 2023-12-07 05:16:15.0 +01:00
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: """
    I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
    \n
    Thanks and no rush, I’ll listen to that article tomorrow :)
    """
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        A Fediverse community for open-ended, thought provoking questions\n
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        **Rules: (interactive)**\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                            +body: """
                              > **Apigenin (herbal supplement)**\n
                              \n
                              Insomnia, anxiety\n
                              \n
                              Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                              """
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                          +body: "Was curious about this since Andrew Huberman mentioned it"
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                        +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                      +body: "Thanks! Is it expensive? How much do you get?"
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                    +body: """
                      Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                      \n
                      I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                      """
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                  +body: "Is that the dose, 1/night before bed?"
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                +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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              +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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            +body: """
              I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
              \n
              I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
              \n
              The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
              \n
              Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
              """
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          +body: """
            Thanks, I’m in talks with the right expert hehe :)\n
            \n
            More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
            """
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            date: 2023-12-23 00:18:32.0 +01:00
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            date: 2023-12-07 05:01:17.0 +01:00
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        +root: App\Entity\EntryComment {#4157}
        +body: "Hahaha, I love working with older folks. They’re my favorite patients."
        +lang: "en"
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          "@Chetzemoka@startrek.website"
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      +root: App\Entity\EntryComment {#4157}
      +body: "Re:Apigenin -> sleep quality?"
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        "@Chetzemoka@startrek.website"
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      }
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        date: 2023-12-07 05:06:34.0 +01:00
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      Here, I found a good article for you:\n
      \n
      [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
      """
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  +body: """
    I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
    \n
    Thanks and no rush, I’ll listen to that article tomorrow :)
    """
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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                          +magazine: App\Entity\Magazine {#265}
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                              +body: """
                                > **Apigenin (herbal supplement)**\n
                                \n
                                Insomnia, anxiety\n
                                \n
                                Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                """
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                            +root: App\Entity\EntryComment {#4157}
                            +body: "Was curious about this since Andrew Huberman mentioned it"
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                          +root: App\Entity\EntryComment {#4157}
                          +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                          -id: 205119
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                            date: 2023-12-07 04:25:07.0 +01:00
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                        }
                        +root: App\Entity\EntryComment {#4157}
                        +body: "Thanks! Is it expensive? How much do you get?"
                        +lang: "en"
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                          "@cheese_greater@lemmy.world"
                          "@Chetzemoka@startrek.website"
                        ]
                        +children: Doctrine\ORM\PersistentCollection {#4675 …}
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                        -bodyTs: "'expens':4 'get':9 'much':6 'thank':1"
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                        +editedAt: DateTimeImmutable @1703285709 {#4672
                          date: 2023-12-22 23:55:09.0 +01:00
                        }
                        +createdAt: DateTimeImmutable @1701919564 {#4673
                          date: 2023-12-07 04:26:04.0 +01:00
                        }
                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: """
                        Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                        \n
                        I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                        """
                      +lang: "en"
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                        date: 2023-12-07 04:43:04.0 +01:00
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
                      ]
                      +children: Doctrine\ORM\PersistentCollection {#4729 …}
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                      -id: 205159
                      -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
                      +ranking: 0
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                        date: 2023-12-07 04:43:04.0 +01:00
                      }
                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Is that the dose, 1/night before bed?"
                    +lang: "en"
                    +isAdult: false
                    +favouriteCount: 2
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                      date: 2023-12-07 04:45:44.0 +01:00
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                      "@cheese_greater@lemmy.world"
                      "@Chetzemoka@startrek.website"
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                    -id: 205164
                    -bodyTs: "'1/night':5 'bed':7 'dose':4"
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                      date: 2023-12-07 04:45:44.0 +01:00
                    }
                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
                  +lang: "en"
                  +isAdult: false
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
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                  -id: 205166
                  -bodyTs: "'200mg':8 'bedtim':13 'dose':7 'hour':11 'like':9 'recommend':6 'usual':5 'yep':1"
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                    date: 2023-12-07 04:47:00.0 +01:00
                  }
                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                +lang: "en"
                +isAdult: false
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                  date: 2023-12-07 04:48:49.0 +01:00
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                  "@cheese_greater@lemmy.world"
                  "@Chetzemoka@startrek.website"
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                -id: 205169
                -bodyTs: "'calm':18 'citrat':28 'd':44 'easier':36 'effect':25 'except':21 'extent':42 'gi':24 'grandmoth':10 'like':12,14,17 'magnesium':19,27 'might':11,34 'particular':8 'recommend':3 'senior':7 'sleep':20 'someth':13 'system':39 'wonder':31 'would':1"
                +ranking: 0
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                +editedAt: null
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                  date: 2023-12-07 04:48:49.0 +01:00
                }
              }
              +root: App\Entity\EntryComment {#4157}
              +body: """
                I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                \n
                I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                \n
                The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                \n
                Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                """
              +lang: "en"
              +isAdult: false
              +favouriteCount: 1
              +score: 0
              +lastActive: DateTime @1701921545 {#4832
                date: 2023-12-07 04:59:05.0 +01:00
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              +ip: null
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
              ]
              +children: Doctrine\ORM\PersistentCollection {#4829 …}
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              -id: 205188
              -bodyTs: "'actual':2 'add':74 'anticholinerg':13 'anymor':128 'blood':32 'bodi':117 'build':113 'call':99 'cardiac':35,141 'caus':110 'cautious':106 'caveat':71 'citrat':60 'common':31 'could':63 'coumadin':101 'definit':78 'doctor':81 'doesn':25 'drug':98 'effect':15,57 'even':107 'folk':39,147 'glycin':51 'help':137 'hope':135 'interact':27 'laxat':56 'less':53 'like':16 'lot':18,149 'm':139 'mag':50,59 'magnesium':48 'med':36 'much':127 'nurs':142 'often':40 'older':38,146 'otc':89 'pharmaceut':20 'pressur':33 'problem':46 'recommend':4 'sedat':21 'senior':7 'side':14 'specif':95 'suck':119 'supplement':49,90 'take':41,84 'tell':79 'tri':64 'two':70 'tylenol':108 'unheard':133 'use':124 'warfarin':100,111,118 'well':67 'work':144 'would':3,73"
              +ranking: 0
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              +editedAt: null
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                date: 2023-12-07 04:59:05.0 +01:00
              }
            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              Thanks, I’m in talks with the right expert hehe :)\n
              \n
              More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
              """
            +lang: "en"
            +isAdult: false
            +favouriteCount: 2
            +score: 0
            +lastActive: DateTime @1701921677 {#4854
              date: 2023-12-07 05:01:17.0 +01:00
            }
            +ip: null
            +tags: null
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
            ]
            +children: Doctrine\ORM\PersistentCollection {#4849 …}
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            -id: 205195
            -bodyTs: "'construct':25 'end':28 'expert':9 'genuin':15 'hehe':10 'help':16 'm':3 'qualiti':18 'right':8 'sleep':20 'specif':12 'talk':5 'thank':1 'thing':23 'toward':26 'turn':30"
            +ranking: 0
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            +apId: "https://lemmy.world/comment/5862964"
            +editedAt: DateTimeImmutable @1703287112 {#4857
              date: 2023-12-23 00:18:32.0 +01:00
            }
            +createdAt: DateTimeImmutable @1701921677 {#4859
              date: 2023-12-07 05:01:17.0 +01:00
            }
          }
          +root: App\Entity\EntryComment {#4157}
          +body: "Hahaha, I love working with older folks. They’re my favorite patients."
          +lang: "en"
          +isAdult: false
          +favouriteCount: 1
          +score: 0
          +lastActive: DateTime @1701921908 {#4877
            date: 2023-12-07 05:05:08.0 +01:00
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
          ]
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          -id: 205200
          -bodyTs: "'favorit':11 'folk':7 'hahaha':1 'love':3 'older':6 'patient':12 're':9 'work':4"
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            date: 2023-12-07 05:05:08.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Re:Apigenin -> sleep quality?"
        +lang: "en"
        +isAdult: false
        +favouriteCount: 1
        +score: 0
        +lastActive: DateTime @1701921994 {#4899
          date: 2023-12-07 05:06:34.0 +01:00
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          "@cheese_greater@lemmy.world"
          "@Chetzemoka@startrek.website"
        ]
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        -id: 205201
        -bodyTs: "'apigenin':2 'qualiti':4 're':1 'sleep':3"
        +ranking: 0
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        +visibility: "visible             "
        +apId: "https://lemmy.world/comment/5863034"
        +editedAt: DateTimeImmutable @1703287271 {#4902
          date: 2023-12-23 00:21:11.0 +01:00
        }
        +createdAt: DateTimeImmutable @1701921994 {#4904
          date: 2023-12-07 05:06:34.0 +01:00
        }
      }
      +root: App\Entity\EntryComment {#4157}
      +body: """
        Here, I found a good article for you:\n
        \n
        [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
        """
      +lang: "en"
      +isAdult: false
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        date: 2023-12-07 05:16:15.0 +01:00
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        "@cheese_greater@lemmy.world"
        "@Chetzemoka@startrek.website"
      ]
      +children: Doctrine\ORM\PersistentCollection {#4937 …}
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      -id: 205227
      -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
      +ranking: 0
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      +createdAt: DateTimeImmutable @1701922575 {#4935
        date: 2023-12-07 05:16:15.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: """
      I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
      \n
      Thanks and no rush, I’ll listen to that article tomorrow :)
      """
    +lang: "en"
    +isAdult: false
    +favouriteCount: 1
    +score: 0
    +lastActive: DateTime @1701922937 {#4971
      date: 2023-12-07 05:22:17.0 +01:00
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      "@cheese_greater@lemmy.world"
      "@Chetzemoka@startrek.website"
    ]
    +children: Doctrine\ORM\PersistentCollection {#4974 …}
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    -id: 205242
    -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
    +ranking: 0
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    +createdAt: DateTimeImmutable @1701922937 {#4972
      date: 2023-12-07 05:22:17.0 +01:00
    }
  }
  +root: App\Entity\EntryComment {#4157}
  +body: """
    So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
    \n
    So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
    \n
    Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
    """
  +lang: "en"
  +isAdult: false
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    "@cheese_greater@lemmy.world"
    "@Chetzemoka@startrek.website"
  ]
  +children: Doctrine\ORM\PersistentCollection {#4995 …}
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  -id: 205267
  -bodyTs: "'/pmc/articles/pmc6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6472148/)':110 'addict':27 'alphabet':101 'also':67 'alzheim':81 'antiinflammatori':71 'apigenin':32 'articl':106 'benzo':44 'benzodiazepin':20 'better':76 'call':45 'consist':36 'could':54 'crawl':98 'depend':29 'doesn':33 'drug':39 'effect':13,59,73 'efficaci':79 'entir':51 'exampl':84 'explain':77 'feel':95 'flumazenil':46 'free':96 'gaba':17,58 'help':61 'host':69 'interest':4 'known':10 'like':21 'lol':107 'neurolog':72 'none':24 'physic':28 'probabl':75 'problem':30 'put':91 're':49 'realli':88 'receptor':18 'research':105 'respond':35 'revers':43 'sleep':63,94 'soup':102 'still':55 'sure':52 'use':41 'want':89 'well':9 'well-known':8 'www.ncbi.nlm.nih.gov':109 'www.ncbi.nlm.nih.gov/pmc/articles/pmc6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6472148/)':108 'xanax':22"
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    date: 2023-12-07 05:31:12.0 +01:00
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}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
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"App\Security\Voter\EntryCommentVoter"
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"App\Security\Voter\EntryVoter"
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"App\Security\Voter\MagazineVoter"
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"App\Security\Voter\MessageThreadVoter"
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"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
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ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
79 DENIED edit
App\Entity\EntryComment {#4987
  +user: App\Entity\User {#4058 …}
  +entry: App\Entity\Entry {#2400
    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
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      > **Generic name (Brand/street name)**\n
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      Discussion paragraphs/submission\n
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      ---\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                              +body: """
                                > **Apigenin (herbal supplement)**\n
                                \n
                                Insomnia, anxiety\n
                                \n
                                Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                """
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                            +body: "Was curious about this since Andrew Huberman mentioned it"
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                          +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                        +body: "Thanks! Is it expensive? How much do you get?"
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                      +body: """
                        Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                        \n
                        I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                        """
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                    +body: "Is that the dose, 1/night before bed?"
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                  +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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              +body: """
                I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                \n
                I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                \n
                The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                \n
                Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                """
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                date: 2023-12-07 04:59:05.0 +01:00
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            +root: App\Entity\EntryComment {#4157}
            +body: """
              Thanks, I’m in talks with the right expert hehe :)\n
              \n
              More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
              """
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              "@Chetzemoka@startrek.website"
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            -bodyTs: "'construct':25 'end':28 'expert':9 'genuin':15 'hehe':10 'help':16 'm':3 'qualiti':18 'right':8 'sleep':20 'specif':12 'talk':5 'thank':1 'thing':23 'toward':26 'turn':30"
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              date: 2023-12-23 00:18:32.0 +01:00
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          +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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        +body: "Re:Apigenin -> sleep quality?"
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      +body: """
        Here, I found a good article for you:\n
        \n
        [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
        """
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    +body: """
      I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
      \n
      Thanks and no rush, I’ll listen to that article tomorrow :)
      """
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  +body: """
    So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
    \n
    So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
    \n
    Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
    """
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                              +body: """
                                > **Apigenin (herbal supplement)**\n
                                \n
                                Insomnia, anxiety\n
                                \n
                                Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                """
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                                date: 2023-12-22 23:57:18.0 +01:00
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                            +body: "Was curious about this since Andrew Huberman mentioned it"
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                              "@Chetzemoka@startrek.website"
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                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                          -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                        +root: App\Entity\EntryComment {#4157}
                        +body: "Thanks! Is it expensive? How much do you get?"
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                      +body: """
                        Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                        \n
                        I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                        """
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                    +body: "Is that the dose, 1/night before bed?"
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                  +root: App\Entity\EntryComment {#4157}
                  +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: """
                I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                \n
                I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                \n
                The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                \n
                Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                """
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            +body: """
              Thanks, I’m in talks with the right expert hehe :)\n
              \n
              More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
              """
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: "Re:Apigenin -> sleep quality?"
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      +body: """
        Here, I found a good article for you:\n
        \n
        [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
        """
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    +body: """
      I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
      \n
      Thanks and no rush, I’ll listen to that article tomorrow :)
      """
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    -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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  +body: """
    So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
    \n
    So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
    \n
    Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
    """
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}
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Show voter details
81 DENIED ROLE_USER
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82 DENIED moderate
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
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        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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  }
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              +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                +user: App\Entity\User {#4058 …}
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                  +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                    +parent: App\Entity\EntryComment {#4765
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                      +magazine: App\Entity\Magazine {#265}
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                      +parent: App\Entity\EntryComment {#4728
                        +user: App\Entity\User {#4058 …}
                        +entry: App\Entity\Entry {#2400}
                        +magazine: App\Entity\Magazine {#265}
                        +image: null
                        +parent: App\Entity\EntryComment {#4674
                          +user: Proxies\__CG__\App\Entity\User {#1978 …}
                          +entry: App\Entity\Entry {#2400}
                          +magazine: App\Entity\Magazine {#265}
                          +image: null
                          +parent: App\Entity\EntryComment {#4606
                            +user: App\Entity\User {#4058 …}
                            +entry: App\Entity\Entry {#2400}
                            +magazine: App\Entity\Magazine {#265}
                            +image: null
                            +parent: App\Entity\EntryComment {#4506
                              +user: Proxies\__CG__\App\Entity\User {#1978 …}
                              +entry: App\Entity\Entry {#2400}
                              +magazine: App\Entity\Magazine {#265}
                              +image: null
                              +parent: App\Entity\EntryComment {#4157
                                +user: App\Entity\User {#4058 …}
                                +entry: App\Entity\Entry {#2400}
                                +magazine: App\Entity\Magazine {#265}
                                +image: null
                                +parent: null
                                +root: null
                                +body: """
                                  > **Apigenin (herbal supplement)**\n
                                  \n
                                  Insomnia, anxiety\n
                                  \n
                                  Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                  """
                                +lang: "en"
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                                  "@cheese_greater@lemmy.world"
                                ]
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                                -id: 205080
                                -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
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                                +createdAt: DateTimeImmutable @1701918902 {#4153
                                  date: 2023-12-07 04:15:02.0 +01:00
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                              }
                              +root: App\Entity\EntryComment {#4157}
                              +body: "Was curious about this since Andrew Huberman mentioned it"
                              +lang: "en"
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                                "@cheese_greater@lemmy.world"
                                "@Chetzemoka@startrek.website"
                              ]
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                              -bodyTs: "'andrew':6 'curious':2 'huberman':7 'mention':8 'sinc':5"
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                                date: 2023-12-07 04:22:46.0 +01:00
                              }
                            }
                            +root: App\Entity\EntryComment {#4157}
                            +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
                            +lang: "en"
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                              "@cheese_greater@lemmy.world"
                              "@Chetzemoka@startrek.website"
                            ]
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                            -id: 205119
                            -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Thanks! Is it expensive? How much do you get?"
                          +lang: "en"
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                            "@cheese_greater@lemmy.world"
                            "@Chetzemoka@startrek.website"
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                            date: 2023-12-22 23:55:09.0 +01:00
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                        +root: App\Entity\EntryComment {#4157}
                        +body: """
                          Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                          \n
                          I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                          """
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                          date: 2023-12-07 04:43:04.0 +01:00
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                          "@cheese_greater@lemmy.world"
                          "@Chetzemoka@startrek.website"
                        ]
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                        -id: 205159
                        -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Is that the dose, 1/night before bed?"
                      +lang: "en"
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                        "@Chetzemoka@startrek.website"
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                      }
                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
                    +lang: "en"
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                      date: 2023-12-07 04:47:00.0 +01:00
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                  +lang: "en"
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                    date: 2023-12-07 04:48:49.0 +01:00
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                +root: App\Entity\EntryComment {#4157}
                +body: """
                  I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                  \n
                  I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                  \n
                  The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                  \n
                  Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                  """
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                  date: 2023-12-07 04:59:05.0 +01:00
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              +root: App\Entity\EntryComment {#4157}
              +body: """
                Thanks, I’m in talks with the right expert hehe :)\n
                \n
                More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                """
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                date: 2023-12-23 00:18:32.0 +01:00
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                date: 2023-12-07 05:01:17.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Hahaha, I love working with older folks. They’re my favorite patients."
            +lang: "en"
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              date: 2023-12-07 05:05:08.0 +01:00
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          +root: App\Entity\EntryComment {#4157}
          +body: "Re:Apigenin -> sleep quality?"
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            date: 2023-12-23 00:21:11.0 +01:00
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            date: 2023-12-07 05:06:34.0 +01:00
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        +root: App\Entity\EntryComment {#4157}
        +body: """
          Here, I found a good article for you:\n
          \n
          [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
          """
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        -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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          date: 2023-12-07 05:16:15.0 +01:00
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      +root: App\Entity\EntryComment {#4157}
      +body: """
        I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
        \n
        Thanks and no rush, I’ll listen to that article tomorrow :)
        """
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      -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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        date: 2023-12-07 05:22:17.0 +01:00
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
      \n
      So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
      \n
      Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
      \n
      [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
    \n
    Thats all for tonight, night
    """
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    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
    +url: null
    +body: """
      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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                            +magazine: App\Entity\Magazine {#265}
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                                +magazine: App\Entity\Magazine {#265}
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                                +body: """
                                  > **Apigenin (herbal supplement)**\n
                                  \n
                                  Insomnia, anxiety\n
                                  \n
                                  Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                  """
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                              +body: "Was curious about this since Andrew Huberman mentioned it"
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                            +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                          +body: "Thanks! Is it expensive? How much do you get?"
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                        +body: """
                          Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                          \n
                          I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                          """
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                      +body: "Is that the dose, 1/night before bed?"
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                    +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                  }
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                  +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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                +body: """
                  I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                  \n
                  I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                  \n
                  The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                  \n
                  Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                  """
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              +body: """
                Thanks, I’m in talks with the right expert hehe :)\n
                \n
                More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                """
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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              date: 2023-12-07 05:05:08.0 +01:00
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          +root: App\Entity\EntryComment {#4157}
          +body: "Re:Apigenin -> sleep quality?"
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            "@Chetzemoka@startrek.website"
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        +body: """
          Here, I found a good article for you:\n
          \n
          [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
          """
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      +body: """
        I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
        \n
        Thanks and no rush, I’ll listen to that article tomorrow :)
        """
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    +body: """
      So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
      \n
      So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
      \n
      Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
      \n
      [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
      """
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  +body: """
    Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
    \n
    Thats all for tonight, night
    """
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                                +body: """
                                  > **Apigenin (herbal supplement)**\n
                                  \n
                                  Insomnia, anxiety\n
                                  \n
                                  Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                  """
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                              +body: "Was curious about this since Andrew Huberman mentioned it"
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                                date: 2023-12-07 04:22:46.0 +01:00
                              }
                            }
                            +root: App\Entity\EntryComment {#4157}
                            +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                              "@Chetzemoka@startrek.website"
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                            -id: 205119
                            -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                            }
                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Thanks! Is it expensive? How much do you get?"
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                            date: 2023-12-22 23:55:09.0 +01:00
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                        +body: """
                          Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                          \n
                          I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                          """
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                          "@cheese_greater@lemmy.world"
                          "@Chetzemoka@startrek.website"
                        ]
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                        -id: 205159
                        -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                      +body: "Is that the dose, 1/night before bed?"
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                    +root: App\Entity\EntryComment {#4157}
                    +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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                    date: 2023-12-07 04:48:49.0 +01:00
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: """
                  I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                  \n
                  I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                  \n
                  The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                  \n
                  Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                  """
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              +root: App\Entity\EntryComment {#4157}
              +body: """
                Thanks, I’m in talks with the right expert hehe :)\n
                \n
                More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                """
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                "@Chetzemoka@startrek.website"
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: "Re:Apigenin -> sleep quality?"
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        +root: App\Entity\EntryComment {#4157}
        +body: """
          Here, I found a good article for you:\n
          \n
          [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
          """
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          "@Chetzemoka@startrek.website"
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        -id: 205227
        -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: """
        I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
        \n
        Thanks and no rush, I’ll listen to that article tomorrow :)
        """
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      -id: 205242
      -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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    +body: """
      So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
      \n
      So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
      \n
      Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
      \n
      [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
    \n
    Thats all for tonight, night
    """
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        A Fediverse community for open-ended, thought provoking questions\n
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        **Rules: (interactive)**\n
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        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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                          +user: App\Entity\User {#4058 …}
                          +entry: App\Entity\Entry {#2400}
                          +magazine: App\Entity\Magazine {#265}
                          +image: null
                          +parent: App\Entity\EntryComment {#4674
                            +user: Proxies\__CG__\App\Entity\User {#1978 …}
                            +entry: App\Entity\Entry {#2400}
                            +magazine: App\Entity\Magazine {#265}
                            +image: null
                            +parent: App\Entity\EntryComment {#4606
                              +user: App\Entity\User {#4058 …}
                              +entry: App\Entity\Entry {#2400}
                              +magazine: App\Entity\Magazine {#265}
                              +image: null
                              +parent: App\Entity\EntryComment {#4506
                                +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                                +magazine: App\Entity\Magazine {#265}
                                +image: null
                                +parent: App\Entity\EntryComment {#4157
                                  +user: App\Entity\User {#4058 …}
                                  +entry: App\Entity\Entry {#2400}
                                  +magazine: App\Entity\Magazine {#265}
                                  +image: null
                                  +parent: null
                                  +root: null
                                  +body: """
                                    > **Apigenin (herbal supplement)**\n
                                    \n
                                    Insomnia, anxiety\n
                                    \n
                                    Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                    """
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                                    "@cheese_greater@lemmy.world"
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                                  -id: 205080
                                  -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
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                                    date: 2023-12-22 23:57:18.0 +01:00
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                                  +createdAt: DateTimeImmutable @1701918902 {#4153
                                    date: 2023-12-07 04:15:02.0 +01:00
                                  }
                                }
                                +root: App\Entity\EntryComment {#4157}
                                +body: "Was curious about this since Andrew Huberman mentioned it"
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                                  "@cheese_greater@lemmy.world"
                                  "@Chetzemoka@startrek.website"
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                                -bodyTs: "'andrew':6 'curious':2 'huberman':7 'mention':8 'sinc':5"
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                                  date: 2023-12-07 04:22:46.0 +01:00
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                              +root: App\Entity\EntryComment {#4157}
                              +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
                              +lang: "en"
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                                "@cheese_greater@lemmy.world"
                                "@Chetzemoka@startrek.website"
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                              -id: 205119
                              -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                                date: 2023-12-07 04:25:07.0 +01:00
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                            +root: App\Entity\EntryComment {#4157}
                            +body: "Thanks! Is it expensive? How much do you get?"
                            +lang: "en"
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                              "@cheese_greater@lemmy.world"
                              "@Chetzemoka@startrek.website"
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                              date: 2023-12-22 23:55:09.0 +01:00
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                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: """
                            Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                            \n
                            I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                            """
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                            "@cheese_greater@lemmy.world"
                            "@Chetzemoka@startrek.website"
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                            date: 2023-12-07 04:43:04.0 +01:00
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                        +root: App\Entity\EntryComment {#4157}
                        +body: "Is that the dose, 1/night before bed?"
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                          date: 2023-12-07 04:45:44.0 +01:00
                        }
                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
                      +lang: "en"
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                        date: 2023-12-07 04:47:00.0 +01:00
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
                      ]
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                      -id: 205166
                      -bodyTs: "'200mg':8 'bedtim':13 'dose':7 'hour':11 'like':9 'recommend':6 'usual':5 'yep':1"
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                        date: 2023-12-07 04:47:00.0 +01:00
                      }
                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                    +lang: "en"
                    +isAdult: false
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                      date: 2023-12-07 04:48:49.0 +01:00
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                      "@cheese_greater@lemmy.world"
                      "@Chetzemoka@startrek.website"
                    ]
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                    +ranking: 0
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                    +apId: "https://lemmy.world/comment/5862796"
                    +editedAt: null
                    +createdAt: DateTimeImmutable @1701920929 {#4813
                      date: 2023-12-07 04:48:49.0 +01:00
                    }
                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: """
                    I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                    \n
                    I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                    \n
                    The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                    \n
                    Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                    """
                  +lang: "en"
                  +isAdult: false
                  +favouriteCount: 1
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                    date: 2023-12-07 04:59:05.0 +01:00
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
                  ]
                  +children: Doctrine\ORM\PersistentCollection {#4829 …}
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                  -id: 205188
                  -bodyTs: "'actual':2 'add':74 'anticholinerg':13 'anymor':128 'blood':32 'bodi':117 'build':113 'call':99 'cardiac':35,141 'caus':110 'cautious':106 'caveat':71 'citrat':60 'common':31 'could':63 'coumadin':101 'definit':78 'doctor':81 'doesn':25 'drug':98 'effect':15,57 'even':107 'folk':39,147 'glycin':51 'help':137 'hope':135 'interact':27 'laxat':56 'less':53 'like':16 'lot':18,149 'm':139 'mag':50,59 'magnesium':48 'med':36 'much':127 'nurs':142 'often':40 'older':38,146 'otc':89 'pharmaceut':20 'pressur':33 'problem':46 'recommend':4 'sedat':21 'senior':7 'side':14 'specif':95 'suck':119 'supplement':49,90 'take':41,84 'tell':79 'tri':64 'two':70 'tylenol':108 'unheard':133 'use':124 'warfarin':100,111,118 'well':67 'work':144 'would':3,73"
                  +ranking: 0
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                    date: 2023-12-07 04:59:05.0 +01:00
                  }
                }
                +root: App\Entity\EntryComment {#4157}
                +body: """
                  Thanks, I’m in talks with the right expert hehe :)\n
                  \n
                  More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                  """
                +lang: "en"
                +isAdult: false
                +favouriteCount: 2
                +score: 0
                +lastActive: DateTime @1701921677 {#4854
                  date: 2023-12-07 05:01:17.0 +01:00
                }
                +ip: null
                +tags: null
                +mentions: [
                  "@cheese_greater@lemmy.world"
                  "@Chetzemoka@startrek.website"
                ]
                +children: Doctrine\ORM\PersistentCollection {#4849 …}
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                -id: 205195
                -bodyTs: "'construct':25 'end':28 'expert':9 'genuin':15 'hehe':10 'help':16 'm':3 'qualiti':18 'right':8 'sleep':20 'specif':12 'talk':5 'thank':1 'thing':23 'toward':26 'turn':30"
                +ranking: 0
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                +apId: "https://lemmy.world/comment/5862964"
                +editedAt: DateTimeImmutable @1703287112 {#4857
                  date: 2023-12-23 00:18:32.0 +01:00
                }
                +createdAt: DateTimeImmutable @1701921677 {#4859
                  date: 2023-12-07 05:01:17.0 +01:00
                }
              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Hahaha, I love working with older folks. They’re my favorite patients."
              +lang: "en"
              +isAdult: false
              +favouriteCount: 1
              +score: 0
              +lastActive: DateTime @1701921908 {#4877
                date: 2023-12-07 05:05:08.0 +01:00
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
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              +children: Doctrine\ORM\PersistentCollection {#4874 …}
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              -id: 205200
              -bodyTs: "'favorit':11 'folk':7 'hahaha':1 'love':3 'older':6 'patient':12 're':9 'work':4"
              +ranking: 0
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                date: 2023-12-07 05:05:08.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: "Re:Apigenin -> sleep quality?"
            +lang: "en"
            +isAdult: false
            +favouriteCount: 1
            +score: 0
            +lastActive: DateTime @1701921994 {#4899
              date: 2023-12-07 05:06:34.0 +01:00
            }
            +ip: null
            +tags: null
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
            ]
            +children: Doctrine\ORM\PersistentCollection {#4894 …}
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            -id: 205201
            -bodyTs: "'apigenin':2 'qualiti':4 're':1 'sleep':3"
            +ranking: 0
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            +visibility: "visible             "
            +apId: "https://lemmy.world/comment/5863034"
            +editedAt: DateTimeImmutable @1703287271 {#4902
              date: 2023-12-23 00:21:11.0 +01:00
            }
            +createdAt: DateTimeImmutable @1701921994 {#4904
              date: 2023-12-07 05:06:34.0 +01:00
            }
          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            Here, I found a good article for you:\n
            \n
            [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
            """
          +lang: "en"
          +isAdult: false
          +favouriteCount: 1
          +score: 0
          +lastActive: DateTime @1701922575 {#4934
            date: 2023-12-07 05:16:15.0 +01:00
          }
          +ip: null
          +tags: null
          +mentions: [
            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
          ]
          +children: Doctrine\ORM\PersistentCollection {#4937 …}
          +nested: Doctrine\ORM\PersistentCollection {#4939 …}
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          -id: 205227
          -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
          +ranking: 0
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          +createdAt: DateTimeImmutable @1701922575 {#4935
            date: 2023-12-07 05:16:15.0 +01:00
          }
        }
        +root: App\Entity\EntryComment {#4157}
        +body: """
          I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
          \n
          Thanks and no rush, I’ll listen to that article tomorrow :)
          """
        +lang: "en"
        +isAdult: false
        +favouriteCount: 1
        +score: 0
        +lastActive: DateTime @1701922937 {#4971
          date: 2023-12-07 05:22:17.0 +01:00
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          "@cheese_greater@lemmy.world"
          "@Chetzemoka@startrek.website"
        ]
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        -id: 205242
        -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
        +ranking: 0
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        +apId: "https://lemmy.world/comment/5863243"
        +editedAt: null
        +createdAt: DateTimeImmutable @1701922937 {#4972
          date: 2023-12-07 05:22:17.0 +01:00
        }
      }
      +root: App\Entity\EntryComment {#4157}
      +body: """
        So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
        \n
        So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
        \n
        Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
        """
      +lang: "en"
      +isAdult: false
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        date: 2023-12-07 05:31:12.0 +01:00
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        "@cheese_greater@lemmy.world"
        "@Chetzemoka@startrek.website"
      ]
      +children: Doctrine\ORM\PersistentCollection {#4995 …}
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      -id: 205267
      -bodyTs: "'/pmc/articles/pmc6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6472148/)':110 'addict':27 'alphabet':101 'also':67 'alzheim':81 'antiinflammatori':71 'apigenin':32 'articl':106 'benzo':44 'benzodiazepin':20 'better':76 'call':45 'consist':36 'could':54 'crawl':98 'depend':29 'doesn':33 'drug':39 'effect':13,59,73 'efficaci':79 'entir':51 'exampl':84 'explain':77 'feel':95 'flumazenil':46 'free':96 'gaba':17,58 'help':61 'host':69 'interest':4 'known':10 'like':21 'lol':107 'neurolog':72 'none':24 'physic':28 'probabl':75 'problem':30 'put':91 're':49 'realli':88 'receptor':18 'research':105 'respond':35 'revers':43 'sleep':63,94 'soup':102 'still':55 'sure':52 'use':41 'want':89 'well':9 'well-known':8 'www.ncbi.nlm.nih.gov':109 'www.ncbi.nlm.nih.gov/pmc/articles/pmc6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6472148/)':108 'xanax':22"
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        date: 2023-12-07 05:31:12.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4157}
    +body: """
      Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
      \n
      Thats all for tonight, night
      """
    +lang: "en"
    +isAdult: false
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      date: 2023-12-07 05:39:15.0 +01:00
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      "@cheese_greater@lemmy.world"
      "@Chetzemoka@startrek.website"
    ]
    +children: Doctrine\ORM\PersistentCollection {#5013 …}
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    -id: 205282
    -bodyTs: "'b':13 'check':5 'displac':11 'flumazenil':10 'gaba':12 'ligands/receptors':14 'night':24 'thank':1 'that':20 'tonight':23 'well':16"
    +ranking: 0
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    +editedAt: DateTimeImmutable @1703291296 {#5021
      date: 2023-12-23 01:28:16.0 +01:00
    }
    +createdAt: DateTimeImmutable @1701923955 {#5023
      date: 2023-12-07 05:39:15.0 +01:00
    }
  }
  +root: App\Entity\EntryComment {#4157}
  +body: """
    Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
    \n
    I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
    """
  +lang: "en"
  +isAdult: false
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    date: 2023-12-07 05:50:36.0 +01:00
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    "@cheese_greater@lemmy.world"
    "@Chetzemoka@startrek.website"
  ]
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  -id: 205304
  -bodyTs: "'/pmc/articles/pmc5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc5326685/)':19 'angri':51 'beyond':37 'breath':42 'bro':57 'check':34 'gaba':15 'get':4 'haha':28 'hahaha':9 'high':55 'like':11 'lol':58 'look':10,24 'm':45 'make':48 'never':31 'oh':1 'primarili':14 're':3,40 'revers':53 'shit':26 'sorri':56 'thought':32 've':30 'weed':7 'www.ncbi.nlm.nih.gov':18 'www.ncbi.nlm.nih.gov/pmc/articles/pmc5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc5326685/)':17"
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    date: 2023-12-07 05:50:36.0 +01:00
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}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
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"App\Security\Voter\EntryCommentVoter"
ACCESS DENIED
"App\Security\Voter\EntryVoter"
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ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
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Show voter details
87 DENIED edit
App\Entity\EntryComment {#5046
  +user: App\Entity\User {#4058 …}
  +entry: App\Entity\Entry {#2400
    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
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        ---\n
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        **Rules: (interactive)**\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        ---\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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                                  +body: """
                                    > **Apigenin (herbal supplement)**\n
                                    \n
                                    Insomnia, anxiety\n
                                    \n
                                    Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                    """
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                                +body: "Was curious about this since Andrew Huberman mentioned it"
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                              +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                            +body: "Thanks! Is it expensive? How much do you get?"
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                          +body: """
                            Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                            \n
                            I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                            """
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                        +body: "Is that the dose, 1/night before bed?"
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                      +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                    +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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                  +body: """
                    I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                    \n
                    I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                    \n
                    The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                    \n
                    Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                    """
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                +root: App\Entity\EntryComment {#4157}
                +body: """
                  Thanks, I’m in talks with the right expert hehe :)\n
                  \n
                  More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                  """
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              +root: App\Entity\EntryComment {#4157}
              +body: "Hahaha, I love working with older folks. They’re my favorite patients."
              +lang: "en"
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            +body: "Re:Apigenin -> sleep quality?"
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          +body: """
            Here, I found a good article for you:\n
            \n
            [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
            """
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        +body: """
          I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
          \n
          Thanks and no rush, I’ll listen to that article tomorrow :)
          """
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          date: 2023-12-07 05:22:17.0 +01:00
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      +body: """
        So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
        \n
        So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
        \n
        Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
        """
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    +body: """
      Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
      \n
      Thats all for tonight, night
      """
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  +body: """
    Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
    \n
    I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
    """
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                                  +magazine: App\Entity\Magazine {#265}
                                  +image: null
                                  +parent: null
                                  +root: null
                                  +body: """
                                    > **Apigenin (herbal supplement)**\n
                                    \n
                                    Insomnia, anxiety\n
                                    \n
                                    Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                    """
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                                    "@cheese_greater@lemmy.world"
                                  ]
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                                  -id: 205080
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                                    date: 2023-12-22 23:57:18.0 +01:00
                                  }
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                                +body: "Was curious about this since Andrew Huberman mentioned it"
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                              +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                            +body: "Thanks! Is it expensive? How much do you get?"
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                          +body: """
                            Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                            \n
                            I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                            """
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                        +body: "Is that the dose, 1/night before bed?"
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                      +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                    }
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                    +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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                  +body: """
                    I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                    \n
                    I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                    \n
                    The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                    \n
                    Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                    """
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                +body: """
                  Thanks, I’m in talks with the right expert hehe :)\n
                  \n
                  More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                  """
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              }
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              +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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            }
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            +body: "Re:Apigenin -> sleep quality?"
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              date: 2023-12-07 05:06:34.0 +01:00
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          +root: App\Entity\EntryComment {#4157}
          +body: """
            Here, I found a good article for you:\n
            \n
            [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
            """
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
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            date: 2023-12-07 05:16:15.0 +01:00
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        +root: App\Entity\EntryComment {#4157}
        +body: """
          I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
          \n
          Thanks and no rush, I’ll listen to that article tomorrow :)
          """
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        -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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          date: 2023-12-07 05:22:17.0 +01:00
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      +body: """
        So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
        \n
        So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
        \n
        Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
        """
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        "@Chetzemoka@startrek.website"
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    +body: """
      Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
      \n
      Thats all for tonight, night
      """
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  +body: """
    Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
    \n
    I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
    """
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                                    +body: """
                                      > **Apigenin (herbal supplement)**\n
                                      \n
                                      Insomnia, anxiety\n
                                      \n
                                      Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                      """
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                                    -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
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                                    +editedAt: DateTimeImmutable @1703285838 {#4152
                                      date: 2023-12-22 23:57:18.0 +01:00
                                    }
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                                  }
                                  +root: App\Entity\EntryComment {#4157}
                                  +body: "Was curious about this since Andrew Huberman mentioned it"
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                                    "@Chetzemoka@startrek.website"
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                                }
                                +root: App\Entity\EntryComment {#4157}
                                +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
                                +lang: "en"
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                                  "@Chetzemoka@startrek.website"
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                                -id: 205119
                                -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                                  date: 2023-12-07 04:25:07.0 +01:00
                                }
                              }
                              +root: App\Entity\EntryComment {#4157}
                              +body: "Thanks! Is it expensive? How much do you get?"
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                                date: 2023-12-22 23:55:09.0 +01:00
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                            +body: """
                              Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                              \n
                              I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                              """
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                              "@cheese_greater@lemmy.world"
                              "@Chetzemoka@startrek.website"
                            ]
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                            -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Is that the dose, 1/night before bed?"
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                            "@Chetzemoka@startrek.website"
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                        +root: App\Entity\EntryComment {#4157}
                        +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                          "@Chetzemoka@startrek.website"
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                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                      +lang: "en"
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                        "@Chetzemoka@startrek.website"
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                        date: 2023-12-07 04:48:49.0 +01:00
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                    }
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                    +body: """
                      I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                      \n
                      I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                      \n
                      The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                      \n
                      Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                      """
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                      "@Chetzemoka@startrek.website"
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: """
                    Thanks, I’m in talks with the right expert hehe :)\n
                    \n
                    More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                    """
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Re:Apigenin -> sleep quality?"
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                "@Chetzemoka@startrek.website"
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              -bodyTs: "'apigenin':2 'qualiti':4 're':1 'sleep':3"
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              Here, I found a good article for you:\n
              \n
              [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
              """
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
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            -id: 205227
            -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
            \n
            Thanks and no rush, I’ll listen to that article tomorrow :)
            """
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
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          -id: 205242
          -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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            date: 2023-12-07 05:22:17.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: """
          So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
          \n
          So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
          \n
          Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
          """
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          "@Chetzemoka@startrek.website"
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          date: 2023-12-07 05:31:12.0 +01:00
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      +root: App\Entity\EntryComment {#4157}
      +body: """
        Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
        \n
        Thats all for tonight, night
        """
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        "@Chetzemoka@startrek.website"
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      -id: 205282
      -bodyTs: "'b':13 'check':5 'displac':11 'flumazenil':10 'gaba':12 'ligands/receptors':14 'night':24 'thank':1 'that':20 'tonight':23 'well':16"
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        date: 2023-12-23 01:28:16.0 +01:00
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        date: 2023-12-07 05:39:15.0 +01:00
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
      \n
      [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
      \n
      I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
    \n
    From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
    """
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        A Fediverse community for open-ended, thought provoking questions\n
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      \n
      Discussion paragraphs/submission\n
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      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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      """
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                                    +body: """
                                      > **Apigenin (herbal supplement)**\n
                                      \n
                                      Insomnia, anxiety\n
                                      \n
                                      Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                      """
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                                  +root: App\Entity\EntryComment {#4157}
                                  +body: "Was curious about this since Andrew Huberman mentioned it"
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                                  }
                                }
                                +root: App\Entity\EntryComment {#4157}
                                +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                                  "@cheese_greater@lemmy.world"
                                  "@Chetzemoka@startrek.website"
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                                -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                              +root: App\Entity\EntryComment {#4157}
                              +body: "Thanks! Is it expensive? How much do you get?"
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                                date: 2023-12-22 23:55:09.0 +01:00
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                            +body: """
                              Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                              \n
                              I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                              """
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                              "@cheese_greater@lemmy.world"
                              "@Chetzemoka@startrek.website"
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                            -id: 205159
                            -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                              date: 2023-12-07 04:43:04.0 +01:00
                            }
                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Is that the dose, 1/night before bed?"
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                        +root: App\Entity\EntryComment {#4157}
                        +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                          "@Chetzemoka@startrek.website"
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                        }
                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
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                        date: 2023-12-07 04:48:49.0 +01:00
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                    }
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                    +body: """
                      I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                      \n
                      I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                      \n
                      The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                      \n
                      Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                      """
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                      "@Chetzemoka@startrek.website"
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: """
                    Thanks, I’m in talks with the right expert hehe :)\n
                    \n
                    More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                    """
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
                  ]
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Re:Apigenin -> sleep quality?"
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                "@Chetzemoka@startrek.website"
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            +root: App\Entity\EntryComment {#4157}
            +body: """
              Here, I found a good article for you:\n
              \n
              [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
              """
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
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            -id: 205227
            -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
            \n
            Thanks and no rush, I’ll listen to that article tomorrow :)
            """
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          -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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        }
        +root: App\Entity\EntryComment {#4157}
        +body: """
          So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
          \n
          So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
          \n
          Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
          """
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          "@Chetzemoka@startrek.website"
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      }
      +root: App\Entity\EntryComment {#4157}
      +body: """
        Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
        \n
        Thats all for tonight, night
        """
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        "@Chetzemoka@startrek.website"
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      -id: 205282
      -bodyTs: "'b':13 'check':5 'displac':11 'flumazenil':10 'gaba':12 'ligands/receptors':14 'night':24 'thank':1 'that':20 'tonight':23 'well':16"
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        date: 2023-12-23 01:28:16.0 +01:00
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        date: 2023-12-07 05:39:15.0 +01:00
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
      \n
      [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
      \n
      I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
    \n
    From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
    """
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        A Fediverse community for open-ended, thought provoking questions\n
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        **Rules: (interactive)**\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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      \n
      Discussion paragraphs/submission\n
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      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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      """
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                                +magazine: App\Entity\Magazine {#265}
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                                +parent: App\Entity\EntryComment {#4506
                                  +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                                    +body: """
                                      > **Apigenin (herbal supplement)**\n
                                      \n
                                      Insomnia, anxiety\n
                                      \n
                                      Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                      """
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                                      date: 2023-12-07 04:15:02.0 +01:00
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                                  +root: App\Entity\EntryComment {#4157}
                                  +body: "Was curious about this since Andrew Huberman mentioned it"
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                                    "@cheese_greater@lemmy.world"
                                    "@Chetzemoka@startrek.website"
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                                +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                                -id: 205119
                                -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                              +body: "Thanks! Is it expensive? How much do you get?"
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                                date: 2023-12-22 23:55:09.0 +01:00
                              }
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                                date: 2023-12-07 04:26:04.0 +01:00
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                            +root: App\Entity\EntryComment {#4157}
                            +body: """
                              Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                              \n
                              I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                              """
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                              date: 2023-12-07 04:43:04.0 +01:00
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                              "@cheese_greater@lemmy.world"
                              "@Chetzemoka@startrek.website"
                            ]
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                            -id: 205159
                            -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                              date: 2023-12-07 04:43:04.0 +01:00
                            }
                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Is that the dose, 1/night before bed?"
                          +lang: "en"
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                            "@Chetzemoka@startrek.website"
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                          -bodyTs: "'1/night':5 'bed':7 'dose':4"
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                        +root: App\Entity\EntryComment {#4157}
                        +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
                        +lang: "en"
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                          "@Chetzemoka@startrek.website"
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                        }
                      }
                      +root: App\Entity\EntryComment {#4157}
                      +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                      +lang: "en"
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                        "@Chetzemoka@startrek.website"
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                        date: 2023-12-07 04:48:49.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: """
                      I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                      \n
                      I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                      \n
                      The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                      \n
                      Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                      """
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                      "@Chetzemoka@startrek.website"
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                  +root: App\Entity\EntryComment {#4157}
                  +body: """
                    Thanks, I’m in talks with the right expert hehe :)\n
                    \n
                    More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                    """
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
                  ]
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                    date: 2023-12-23 00:18:32.0 +01:00
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Hahaha, I love working with older folks. They’re my favorite patients."
                +lang: "en"
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: "Re:Apigenin -> sleep quality?"
              +lang: "en"
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                date: 2023-12-07 05:06:34.0 +01:00
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                "@Chetzemoka@startrek.website"
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            +root: App\Entity\EntryComment {#4157}
            +body: """
              Here, I found a good article for you:\n
              \n
              [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
              """
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
            ]
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            -id: 205227
            -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
            \n
            Thanks and no rush, I’ll listen to that article tomorrow :)
            """
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
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          -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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        +body: """
          So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
          \n
          So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
          \n
          Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
          """
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          "@Chetzemoka@startrek.website"
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      }
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      +body: """
        Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
        \n
        Thats all for tonight, night
        """
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      -id: 205282
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    }
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    +body: """
      Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
      \n
      [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
      \n
      I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
    \n
    From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
    """
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}
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        **Rules: (interactive)**\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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                                +magazine: App\Entity\Magazine {#265}
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                                  +entry: App\Entity\Entry {#2400}
                                  +magazine: App\Entity\Magazine {#265}
                                  +image: null
                                  +parent: App\Entity\EntryComment {#4506
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                                      +magazine: App\Entity\Magazine {#265}
                                      +image: null
                                      +parent: null
                                      +root: null
                                      +body: """
                                        > **Apigenin (herbal supplement)**\n
                                        \n
                                        Insomnia, anxiety\n
                                        \n
                                        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                        """
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                                    +root: App\Entity\EntryComment {#4157}
                                    +body: "Was curious about this since Andrew Huberman mentioned it"
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                                      "@cheese_greater@lemmy.world"
                                      "@Chetzemoka@startrek.website"
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                                  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                                  -id: 205119
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                                +body: "Thanks! Is it expensive? How much do you get?"
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                              }
                              +root: App\Entity\EntryComment {#4157}
                              +body: """
                                Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                                \n
                                I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                                """
                              +lang: "en"
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                                "@cheese_greater@lemmy.world"
                                "@Chetzemoka@startrek.website"
                              ]
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                              -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                            +root: App\Entity\EntryComment {#4157}
                            +body: "Is that the dose, 1/night before bed?"
                            +lang: "en"
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                            -bodyTs: "'1/night':5 'bed':7 'dose':4"
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                          +root: App\Entity\EntryComment {#4157}
                          +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                          }
                        }
                        +root: App\Entity\EntryComment {#4157}
                        +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                        +lang: "en"
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                          "@Chetzemoka@startrek.website"
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                      +body: """
                        I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                        \n
                        I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                        \n
                        The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                        \n
                        Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                        """
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
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                    +body: """
                      Thanks, I’m in talks with the right expert hehe :)\n
                      \n
                      More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                      """
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                      "@cheese_greater@lemmy.world"
                      "@Chetzemoka@startrek.website"
                    ]
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                      date: 2023-12-23 00:18:32.0 +01:00
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                    }
                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Hahaha, I love working with older folks. They’re my favorite patients."
                  +lang: "en"
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Re:Apigenin -> sleep quality?"
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                  date: 2023-12-07 05:06:34.0 +01:00
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              +root: App\Entity\EntryComment {#4157}
              +body: """
                Here, I found a good article for you:\n
                \n
                [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
                """
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
              ]
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              -id: 205227
              -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
              \n
              Thanks and no rush, I’ll listen to that article tomorrow :)
              """
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
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            -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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          +body: """
            So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
            \n
            So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
            \n
            Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
            \n
            [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
            """
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            "@Chetzemoka@startrek.website"
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        +body: """
          Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
          \n
          Thats all for tonight, night
          """
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      }
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      +body: """
        Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
        \n
        I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
        """
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    +body: """
      It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
      \n
      From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
      """
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  +body: """
    Huh, now that’s super interesting.\n
    \n
    Ok you and I both have to go to sleep, but now you’ve got me wondering about the eternal debate amongst our medical residents about benzos vs. barbiturates for acute alcohol withdrawal. I’ll have to read up on this some more
    """
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        A Fediverse community for open-ended, thought provoking questions\n
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        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      \n
      Discussion paragraphs/submission\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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      """
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                                  +entry: App\Entity\Entry {#2400}
                                  +magazine: App\Entity\Magazine {#265}
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                                      +image: null
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                                      +body: """
                                        > **Apigenin (herbal supplement)**\n
                                        \n
                                        Insomnia, anxiety\n
                                        \n
                                        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                        """
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                                    +body: "Was curious about this since Andrew Huberman mentioned it"
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                                  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                                +body: "Thanks! Is it expensive? How much do you get?"
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                              +root: App\Entity\EntryComment {#4157}
                              +body: """
                                Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                                \n
                                I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                                """
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                                "@cheese_greater@lemmy.world"
                                "@Chetzemoka@startrek.website"
                              ]
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                              -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                                date: 2023-12-07 04:43:04.0 +01:00
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                            }
                            +root: App\Entity\EntryComment {#4157}
                            +body: "Is that the dose, 1/night before bed?"
                            +lang: "en"
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                              "@Chetzemoka@startrek.website"
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                            -bodyTs: "'1/night':5 'bed':7 'dose':4"
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                          +root: App\Entity\EntryComment {#4157}
                          +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                          }
                        }
                        +root: App\Entity\EntryComment {#4157}
                        +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                        +lang: "en"
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                          "@Chetzemoka@startrek.website"
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                      +body: """
                        I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                        \n
                        I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                        \n
                        The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                        \n
                        Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                        """
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
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                    +body: """
                      Thanks, I’m in talks with the right expert hehe :)\n
                      \n
                      More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                      """
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                      "@cheese_greater@lemmy.world"
                      "@Chetzemoka@startrek.website"
                    ]
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                      date: 2023-12-23 00:18:32.0 +01:00
                    }
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                    }
                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Hahaha, I love working with older folks. They’re my favorite patients."
                  +lang: "en"
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Re:Apigenin -> sleep quality?"
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                  date: 2023-12-07 05:06:34.0 +01:00
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                  "@Chetzemoka@startrek.website"
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                }
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              +root: App\Entity\EntryComment {#4157}
              +body: """
                Here, I found a good article for you:\n
                \n
                [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
                """
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
              ]
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              -id: 205227
              -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
              \n
              Thanks and no rush, I’ll listen to that article tomorrow :)
              """
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
            ]
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            -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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              date: 2023-12-07 05:22:17.0 +01:00
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
            \n
            So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
            \n
            Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
            \n
            [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
            """
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
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        +body: """
          Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
          \n
          Thats all for tonight, night
          """
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      }
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      +body: """
        Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
        \n
        I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
        """
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    +body: """
      It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
      \n
      From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
      """
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      "@Chetzemoka@startrek.website"
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  }
  +root: App\Entity\EntryComment {#4157}
  +body: """
    Huh, now that’s super interesting.\n
    \n
    Ok you and I both have to go to sleep, but now you’ve got me wondering about the eternal debate amongst our medical residents about benzos vs. barbiturates for acute alcohol withdrawal. I’ll have to read up on this some more
    """
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}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
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"App\Security\Voter\EntryCommentVoter"
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Show voter details
96 DENIED moderate
App\Entity\EntryComment {#5090
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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                            +magazine: App\Entity\Magazine {#265}
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                              +magazine: App\Entity\Magazine {#265}
                              +image: null
                              +parent: App\Entity\EntryComment {#4674
                                +user: Proxies\__CG__\App\Entity\User {#1978 …}
                                +entry: App\Entity\Entry {#2400}
                                +magazine: App\Entity\Magazine {#265}
                                +image: null
                                +parent: App\Entity\EntryComment {#4606
                                  +user: App\Entity\User {#4058 …}
                                  +entry: App\Entity\Entry {#2400}
                                  +magazine: App\Entity\Magazine {#265}
                                  +image: null
                                  +parent: App\Entity\EntryComment {#4506
                                    +user: Proxies\__CG__\App\Entity\User {#1978 …}
                                    +entry: App\Entity\Entry {#2400}
                                    +magazine: App\Entity\Magazine {#265}
                                    +image: null
                                    +parent: App\Entity\EntryComment {#4157
                                      +user: App\Entity\User {#4058 …}
                                      +entry: App\Entity\Entry {#2400}
                                      +magazine: App\Entity\Magazine {#265}
                                      +image: null
                                      +parent: null
                                      +root: null
                                      +body: """
                                        > **Apigenin (herbal supplement)**\n
                                        \n
                                        Insomnia, anxiety\n
                                        \n
                                        Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                        """
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                                        "@cheese_greater@lemmy.world"
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                                      -bodyTs: "'anxieti':5 'apigenin':1 'believ':34 'chamomil':8 'chronic':25 'deriv':6 'flower':9 'found':16 'herbal':2 'insomnia':4,26 'option':32 'pharmaceut':31 'plant':12 'sourc':13 'success':21 'supplement':3 'treat':23 'tri':38 've':15,37"
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                                      }
                                      +createdAt: DateTimeImmutable @1701918902 {#4153
                                        date: 2023-12-07 04:15:02.0 +01:00
                                      }
                                    }
                                    +root: App\Entity\EntryComment {#4157}
                                    +body: "Was curious about this since Andrew Huberman mentioned it"
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                                      "@cheese_greater@lemmy.world"
                                      "@Chetzemoka@startrek.website"
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                                  }
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                                  +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                                    "@cheese_greater@lemmy.world"
                                    "@Chetzemoka@startrek.website"
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                                  -id: 205119
                                  -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                                    date: 2023-12-07 04:25:07.0 +01:00
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                                }
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                                +body: "Thanks! Is it expensive? How much do you get?"
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                                  "@cheese_greater@lemmy.world"
                                  "@Chetzemoka@startrek.website"
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                                  date: 2023-12-22 23:55:09.0 +01:00
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                              }
                              +root: App\Entity\EntryComment {#4157}
                              +body: """
                                Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                                \n
                                I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                                """
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                                "@cheese_greater@lemmy.world"
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                              -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                                date: 2023-12-07 04:43:04.0 +01:00
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                            +root: App\Entity\EntryComment {#4157}
                            +body: "Is that the dose, 1/night before bed?"
                            +lang: "en"
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                              "@cheese_greater@lemmy.world"
                              "@Chetzemoka@startrek.website"
                            ]
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                            -bodyTs: "'1/night':5 'bed':7 'dose':4"
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                          +root: App\Entity\EntryComment {#4157}
                          +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                          }
                        }
                        +root: App\Entity\EntryComment {#4157}
                        +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                        +lang: "en"
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                          "@Chetzemoka@startrek.website"
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                      +body: """
                        I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                        \n
                        I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                        \n
                        The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                        \n
                        Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                        """
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
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                    +body: """
                      Thanks, I’m in talks with the right expert hehe :)\n
                      \n
                      More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                      """
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                      "@cheese_greater@lemmy.world"
                      "@Chetzemoka@startrek.website"
                    ]
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                      date: 2023-12-23 00:18:32.0 +01:00
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                    }
                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Hahaha, I love working with older folks. They’re my favorite patients."
                  +lang: "en"
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: "Re:Apigenin -> sleep quality?"
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                  date: 2023-12-07 05:06:34.0 +01:00
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                  "@Chetzemoka@startrek.website"
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                }
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              +root: App\Entity\EntryComment {#4157}
              +body: """
                Here, I found a good article for you:\n
                \n
                [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
                """
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
              ]
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              -id: 205227
              -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
              \n
              Thanks and no rush, I’ll listen to that article tomorrow :)
              """
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
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            -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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              date: 2023-12-07 05:22:17.0 +01:00
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          }
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          +body: """
            So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
            \n
            So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
            \n
            Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
            \n
            [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
            """
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            "@cheese_greater@lemmy.world"
            "@Chetzemoka@startrek.website"
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        +body: """
          Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
          \n
          Thats all for tonight, night
          """
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      }
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      +body: """
        Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
        \n
        [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
        \n
        I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
        """
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    +body: """
      It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
      \n
      From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
      """
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      "@Chetzemoka@startrek.website"
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    Huh, now that’s super interesting.\n
    \n
    Ok you and I both have to go to sleep, but now you’ve got me wondering about the eternal debate amongst our medical residents about benzos vs. barbiturates for acute alcohol withdrawal. I’ll have to read up on this some more
    """
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}
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97 DENIED ROLE_USER
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
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        ---\n
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        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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                                +user: App\Entity\User {#4058 …}
                                +entry: App\Entity\Entry {#2400}
                                +magazine: App\Entity\Magazine {#265}
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                                +parent: App\Entity\EntryComment {#4674
                                  +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                                  +magazine: App\Entity\Magazine {#265}
                                  +image: null
                                  +parent: App\Entity\EntryComment {#4606
                                    +user: App\Entity\User {#4058 …}
                                    +entry: App\Entity\Entry {#2400}
                                    +magazine: App\Entity\Magazine {#265}
                                    +image: null
                                    +parent: App\Entity\EntryComment {#4506
                                      +user: Proxies\__CG__\App\Entity\User {#1978 …}
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                                      +magazine: App\Entity\Magazine {#265}
                                      +image: null
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                                        +magazine: App\Entity\Magazine {#265}
                                        +image: null
                                        +parent: null
                                        +root: null
                                        +body: """
                                          > **Apigenin (herbal supplement)**\n
                                          \n
                                          Insomnia, anxiety\n
                                          \n
                                          Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                          """
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                                      +root: App\Entity\EntryComment {#4157}
                                      +body: "Was curious about this since Andrew Huberman mentioned it"
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                                        "@cheese_greater@lemmy.world"
                                        "@Chetzemoka@startrek.website"
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                                    +root: App\Entity\EntryComment {#4157}
                                    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                                      "@cheese_greater@lemmy.world"
                                      "@Chetzemoka@startrek.website"
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                                    -id: 205119
                                    -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                                      date: 2023-12-07 04:25:07.0 +01:00
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                                  }
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                                  +body: "Thanks! Is it expensive? How much do you get?"
                                  +lang: "en"
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                                    "@cheese_greater@lemmy.world"
                                    "@Chetzemoka@startrek.website"
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                                    date: 2023-12-22 23:55:09.0 +01:00
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                                }
                                +root: App\Entity\EntryComment {#4157}
                                +body: """
                                  Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                                  \n
                                  I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                                  """
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                                  "@cheese_greater@lemmy.world"
                                  "@Chetzemoka@startrek.website"
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                                -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                                  date: 2023-12-07 04:43:04.0 +01:00
                                }
                              }
                              +root: App\Entity\EntryComment {#4157}
                              +body: "Is that the dose, 1/night before bed?"
                              +lang: "en"
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                              -bodyTs: "'1/night':5 'bed':7 'dose':4"
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                            +root: App\Entity\EntryComment {#4157}
                            +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                            }
                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                          +lang: "en"
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                            "@Chetzemoka@startrek.website"
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                        +body: """
                          I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                          \n
                          I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                          \n
                          The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                          \n
                          Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                          """
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                          "@Chetzemoka@startrek.website"
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                      +body: """
                        Thanks, I’m in talks with the right expert hehe :)\n
                        \n
                        More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                        """
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
                      ]
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                        date: 2023-12-23 00:18:32.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Re:Apigenin -> sleep quality?"
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                    date: 2023-12-07 05:06:34.0 +01:00
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
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                  }
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                +root: App\Entity\EntryComment {#4157}
                +body: """
                  Here, I found a good article for you:\n
                  \n
                  [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
                  """
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                  "@cheese_greater@lemmy.world"
                  "@Chetzemoka@startrek.website"
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                -id: 205227
                -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: """
                I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
                \n
                Thanks and no rush, I’ll listen to that article tomorrow :)
                """
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
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              -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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            +body: """
              So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
              \n
              So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
              \n
              Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
              \n
              [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
              """
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
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          +body: """
            Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
            \n
            Thats all for tonight, night
            """
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        }
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        +body: """
          Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
          \n
          I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
          """
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      +body: """
        It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
        \n
        From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
        """
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    +body: """
      Huh, now that’s super interesting.\n
      \n
      Ok you and I both have to go to sleep, but now you’ve got me wondering about the eternal debate amongst our medical residents about benzos vs. barbiturates for acute alcohol withdrawal. I’ll have to read up on this some more
      """
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  +root: App\Entity\EntryComment {#4157}
  +body: """
    Yeah, ask about baclofen, its famously advocated by a French dr who struggled to find a proper treatment for his alcoholism until he arrived on baclofen. `End of My Addiction` is the title.\n
    \n
    I used it as an adjuvant treatment along with naltrexone and careful timing in terms of the actual drinking that was required to make the naltrexone effective in addressing the neurochemical basis for much of the compulsion from alcohol.
    """
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        A Fediverse community for open-ended, thought provoking questions\n
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        ---\n
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        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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                                    +magazine: App\Entity\Magazine {#265}
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                                        +body: """
                                          > **Apigenin (herbal supplement)**\n
                                          \n
                                          Insomnia, anxiety\n
                                          \n
                                          Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                          """
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                                      +root: App\Entity\EntryComment {#4157}
                                      +body: "Was curious about this since Andrew Huberman mentioned it"
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                                        "@cheese_greater@lemmy.world"
                                        "@Chetzemoka@startrek.website"
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                                    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                                  +body: "Thanks! Is it expensive? How much do you get?"
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                                    date: 2023-12-22 23:55:09.0 +01:00
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                                +body: """
                                  Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                                  \n
                                  I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                                  """
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                                  date: 2023-12-07 04:43:04.0 +01:00
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                                  "@cheese_greater@lemmy.world"
                                  "@Chetzemoka@startrek.website"
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                                -id: 205159
                                -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                                  date: 2023-12-07 04:43:04.0 +01:00
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                              }
                              +root: App\Entity\EntryComment {#4157}
                              +body: "Is that the dose, 1/night before bed?"
                              +lang: "en"
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                            +root: App\Entity\EntryComment {#4157}
                            +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
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                            }
                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                          +lang: "en"
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                        +body: """
                          I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                          \n
                          I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                          \n
                          The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                          \n
                          Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                          """
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                      +body: """
                        Thanks, I’m in talks with the right expert hehe :)\n
                        \n
                        More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                        """
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
                      ]
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Re:Apigenin -> sleep quality?"
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                +root: App\Entity\EntryComment {#4157}
                +body: """
                  Here, I found a good article for you:\n
                  \n
                  [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
                  """
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                  "@cheese_greater@lemmy.world"
                  "@Chetzemoka@startrek.website"
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                -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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              +root: App\Entity\EntryComment {#4157}
              +body: """
                I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
                \n
                Thanks and no rush, I’ll listen to that article tomorrow :)
                """
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              -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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            +body: """
              So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
              \n
              So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
              \n
              Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
              \n
              [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
              """
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              "@Chetzemoka@startrek.website"
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          +body: """
            Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
            \n
            Thats all for tonight, night
            """
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        }
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        +body: """
          Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
          \n
          I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
          """
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        -bodyTs: "'/pmc/articles/pmc5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc5326685/)':19 'angri':51 'beyond':37 'breath':42 'bro':57 'check':34 'gaba':15 'get':4 'haha':28 'hahaha':9 'high':55 'like':11 'lol':58 'look':10,24 'm':45 'make':48 'never':31 'oh':1 'primarili':14 're':3,40 'revers':53 'shit':26 'sorri':56 'thought':32 've':30 'weed':7 'www.ncbi.nlm.nih.gov':18 'www.ncbi.nlm.nih.gov/pmc/articles/pmc5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/pmc5326685/)':17"
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          date: 2023-12-07 05:50:36.0 +01:00
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      +body: """
        It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
        \n
        From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
        """
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    +body: """
      Huh, now that’s super interesting.\n
      \n
      Ok you and I both have to go to sleep, but now you’ve got me wondering about the eternal debate amongst our medical residents about benzos vs. barbiturates for acute alcohol withdrawal. I’ll have to read up on this some more
      """
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  +body: """
    Yeah, ask about baclofen, its famously advocated by a French dr who struggled to find a proper treatment for his alcoholism until he arrived on baclofen. `End of My Addiction` is the title.\n
    \n
    I used it as an adjuvant treatment along with naltrexone and careful timing in terms of the actual drinking that was required to make the naltrexone effective in addressing the neurochemical basis for much of the compulsion from alcohol.
    """
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      Discussion paragraphs/submission\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
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                                        +body: """
                                          > **Apigenin (herbal supplement)**\n
                                          \n
                                          Insomnia, anxiety\n
                                          \n
                                          Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)
                                          """
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                                      +root: App\Entity\EntryComment {#4157}
                                      +body: "Was curious about this since Andrew Huberman mentioned it"
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                                        "@cheese_greater@lemmy.world"
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                                    +body: "It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me."
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                                      "@Chetzemoka@startrek.website"
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                                    -id: 205119
                                    -bodyTs: "'400mg/night':29 'absolut':7 'advertis':38,47 'dosag':34 'dose':9,15 'even':5 'gram':19 'high':22 'larg':8 'like':55 'll':36 'low':52 'mention':41 'multipl':18 'peopl':54 'perform':13 'person':26 'probabl':50 'rang':20,48 'realli':3 'recommend':23 'safe':4 'see':37 'standard':46 'studi':12 'take':28 'think':44 'tri':24 'twice':32 'use':14"
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                                  }
                                  +root: App\Entity\EntryComment {#4157}
                                  +body: "Thanks! Is it expensive? How much do you get?"
                                  +lang: "en"
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                                    date: 2023-12-22 23:55:09.0 +01:00
                                  }
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                                +body: """
                                  Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha\n
                                  \n
                                  I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.
                                  """
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                                  "@cheese_greater@lemmy.world"
                                  "@Chetzemoka@startrek.website"
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                                -id: 205159
                                -bodyTs: "'20':33 '200mg':40 '30':36 'bold':18 'bottl':38 'brain':10 'capsul':41 'challeng':6 'citizen':9 'compani':28 'count':37 'depot':24 'haha':20 'know':15 'like':22 'man':2 'nootrop':23 'oh':1 'realli':5 'sell':30 'senior':8 'sourc':27 'thing':19 'think':13"
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                                  date: 2023-12-07 04:43:04.0 +01:00
                                }
                              }
                              +root: App\Entity\EntryComment {#4157}
                              +body: "Is that the dose, 1/night before bed?"
                              +lang: "en"
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                              -bodyTs: "'1/night':5 'bed':7 'dose':4"
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                            +root: App\Entity\EntryComment {#4157}
                            +body: "Yep, that’s the usual recommended dose - 200mg like an hour before bedtime"
                            +lang: "en"
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                            }
                          }
                          +root: App\Entity\EntryComment {#4157}
                          +body: "Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it"
                          +lang: "en"
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                        +body: """
                          I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.\n
                          \n
                          I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.\n
                          \n
                          The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)\n
                          \n
                          Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)
                          """
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                          "@Chetzemoka@startrek.website"
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                      +body: """
                        Thanks, I’m in talks with the right expert hehe :)\n
                        \n
                        More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?
                        """
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                        "@cheese_greater@lemmy.world"
                        "@Chetzemoka@startrek.website"
                      ]
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                        date: 2023-12-23 00:18:32.0 +01:00
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                    }
                    +root: App\Entity\EntryComment {#4157}
                    +body: "Hahaha, I love working with older folks. They’re my favorite patients."
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                  }
                  +root: App\Entity\EntryComment {#4157}
                  +body: "Re:Apigenin -> sleep quality?"
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                    date: 2023-12-07 05:06:34.0 +01:00
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                    "@cheese_greater@lemmy.world"
                    "@Chetzemoka@startrek.website"
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                  -bodyTs: "'apigenin':2 'qualiti':4 're':1 'sleep':3"
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                }
                +root: App\Entity\EntryComment {#4157}
                +body: """
                  Here, I found a good article for you:\n
                  \n
                  [uspharmacist.com/…/assisting-seniors-with-insomni…](https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)
                  """
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                  "@cheese_greater@lemmy.world"
                  "@Chetzemoka@startrek.website"
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                -id: 205227
                -bodyTs: "'/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':13 '/assisting-seniors-with-insomni':10 'articl':6 'found':3 'good':5 'uspharmacist.com':9 'www.uspharmacist.com':12 'www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach)':11"
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              }
              +root: App\Entity\EntryComment {#4157}
              +body: """
                I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?\n
                \n
                Thanks and no rush, I’ll listen to that article tomorrow :)
                """
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                "@cheese_greater@lemmy.world"
                "@Chetzemoka@startrek.website"
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              -id: 205242
              -bodyTs: "'aha':5 'apigenin':22 'articl':49 'behind':32 'efficaci':24,34 'gotta':2 'last':13 'leav':9 'like':27 'listen':46 'll':8,45 'mechan':31 'mediat':21 'modul':39 'question':14 'rush':43 'sleep':3,26 'soon':4 'system':36 'thank':40 'think':20 'tomorrow':50 'tonight':16"
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                date: 2023-12-07 05:22:17.0 +01:00
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            }
            +root: App\Entity\EntryComment {#4157}
            +body: """
              So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).\n
              \n
              So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.\n
              \n
              Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:\n
              \n
              [www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/)
              """
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              "@cheese_greater@lemmy.world"
              "@Chetzemoka@startrek.website"
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          }
          +root: App\Entity\EntryComment {#4157}
          +body: """
            Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?\n
            \n
            Thats all for tonight, night
            """
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            "@Chetzemoka@startrek.website"
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          -bodyTs: "'b':13 'check':5 'displac':11 'flumazenil':10 'gaba':12 'ligands/receptors':14 'night':24 'thank':1 'that':20 'tonight':23 'well':16"
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            date: 2023-12-23 01:28:16.0 +01:00
          }
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            date: 2023-12-07 05:39:15.0 +01:00
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        +root: App\Entity\EntryComment {#4157}
        +body: """
          Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A\n
          \n
          [www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/)\n
          \n
          I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol
          """
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      +root: App\Entity\EntryComment {#4157}
      +body: """
        It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that\n
        \n
        From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
        """
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        date: 2023-12-07 05:57:54.0 +01:00
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    +root: App\Entity\EntryComment {#4157}
    +body: """
      Huh, now that’s super interesting.\n
      \n
      Ok you and I both have to go to sleep, but now you’ve got me wondering about the eternal debate amongst our medical residents about benzos vs. barbiturates for acute alcohol withdrawal. I’ll have to read up on this some more
      """
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    Yeah, ask about baclofen, its famously advocated by a French dr who struggled to find a proper treatment for his alcoholism until he arrived on baclofen. `End of My Addiction` is the title.\n
    \n
    I used it as an adjuvant treatment along with naltrexone and careful timing in terms of the actual drinking that was required to make the naltrexone effective in addressing the neurochemical basis for much of the compulsion from alcohol.
    """
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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    > **Pregabalin (Lyrica)**\n
    \n
    Fascinating medication that I have found to annihilate anxiety (excellent anxiolytic) and promote social cohesion/sociabillity/oversharing beware. Takes the edge of stimulants as well\n
    \n
    Almost like a pharmaceutical slightly sedative-leaning version of ecstasy but obviously quite distinct pharmacologically and not a replacement for same.
    """
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        A Fediverse community for open-ended, thought provoking questions\n
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        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        \n
        ---\n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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111 DENIED edit
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        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        ---\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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112 DENIED moderate
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        \n
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        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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    I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
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Show voter details
114 DENIED moderate
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        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      \n
      I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
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  +root: App\Entity\EntryComment {#4188}
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    > GHB\n
    \n
    It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
    """
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ACCESS ABSTAIN
Show voter details
115 DENIED edit
App\Entity\EntryComment {#4559
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        ---\n
        \n
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        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        \n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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        > **Trazodone (Desyrel)**\n
        \n
        [in relation to deep sleep promotion]
        """
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      As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
      \n
      I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
      """
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  +root: App\Entity\EntryComment {#4188}
  +body: """
    > GHB\n
    \n
    It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
    """
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}
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ACCESS ABSTAIN
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ACCESS DENIED
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
116 DENIED moderate
App\Entity\EntryComment {#4559
  +user: Proxies\__CG__\App\Entity\User {#1978 …}
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
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        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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    +user: App\Entity\User {#4359 …}
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      +body: """
        > **Trazodone (Desyrel)**\n
        \n
        [in relation to deep sleep promotion]
        """
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        date: 2023-12-07 02:04:23.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4188}
    +body: """
      As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
      \n
      I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
      """
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    > GHB\n
    \n
    It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
    """
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        ---\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      \n
      Discussion paragraphs/submission\n
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      \n
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      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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          > **Trazodone (Desyrel)**\n
          \n
          [in relation to deep sleep promotion]
          """
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      +body: """
        As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
        \n
        I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
        """
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        date: 2023-12-07 03:20:45.0 +01:00
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    +body: """
      > GHB\n
      \n
      It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
      """
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      date: 2023-12-07 03:40:04.0 +01:00
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  }
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  +body: "That's the one. Very effective for people like me, but not very available."
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}
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Show voter details
119 DENIED edit
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
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          > **Trazodone (Desyrel)**\n
          \n
          [in relation to deep sleep promotion]
          """
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        As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
        \n
        I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
        """
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      > GHB\n
      \n
      It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
      """
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  +body: "That's the one. Very effective for people like me, but not very available."
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ACCESS ABSTAIN
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"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
Show voter details
120 DENIED moderate
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
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        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        -id: 204823
        -bodyTs: "'deep':6 'desyrel':2 'promot':8 'relat':4 'sleep':7 'trazodon':1"
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          date: 2023-12-22 19:47:36.0 +01:00
        }
        +createdAt: DateTimeImmutable @1701911063 {#4154
          date: 2023-12-07 02:04:23.0 +01:00
        }
      }
      +root: App\Entity\EntryComment {#4188}
      +body: """
        As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
        \n
        I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
        """
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        "@cheese_greater@lemmy.world"
      ]
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      -id: 204982
      -bodyTs: "'appar':48 'asleep':17,29,37,60,65 'basic':49 'common':68,76 'date':69 'doctor':44 'doesn':32 'drug':71 'fall':16,28,64 'find':21 'frequent':10 'good':55 'help':24,27,34,57 'night':13 'one':35 'oppos':62 'prescrib':77 'primari':7 'problem':8 'rape':70 'rather':14 'sleep':43 'somebodi':58 'spoken':40 'stay':36,59 'thing':52 'user':3 've':39 'wake':11 'whose':6"
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        date: 2023-12-07 03:20:45.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4188}
    +body: """
      > GHB\n
      \n
      It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
      """
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      date: 2023-12-07 03:40:04.0 +01:00
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  }
  +root: App\Entity\EntryComment {#4188}
  +body: "That's the one. Very effective for people like me, but not very available."
  +lang: "en"
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}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
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"App\Security\Voter\EntryCommentVoter"
ACCESS DENIED
"App\Security\Voter\EntryVoter"
ACCESS ABSTAIN
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
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"App\Security\Voter\NotificationVoter"
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"App\Security\Voter\OAuth2UserConsentVoter"
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"App\Security\Voter\PostCommentVoter"
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"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
121 DENIED ROLE_USER
null
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"Symfony\Component\Security\Core\Authorization\Voter\RoleHierarchyVoter"
ACCESS DENIED
"App\Security\Voter\EntryCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryVoter"
ACCESS ABSTAIN
"App\Security\Voter\MagazineVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostCommentVoter"
ACCESS ABSTAIN
"App\Security\Voter\PostVoter"
ACCESS ABSTAIN
"App\Security\Voter\UserVoter"
ACCESS ABSTAIN
Show voter details
122 DENIED moderate
App\Entity\EntryComment {#4696
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
    +type: "article"
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  }
  +magazine: App\Entity\Magazine {#265}
  +image: null
  +parent: App\Entity\EntryComment {#4643
    +user: App\Entity\User {#4359 …}
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    +magazine: App\Entity\Magazine {#265}
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    +parent: App\Entity\EntryComment {#4559
      +user: Proxies\__CG__\App\Entity\User {#1978 …}
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        +user: App\Entity\User {#4359 …}
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        +parent: App\Entity\EntryComment {#4188
          +user: Proxies\__CG__\App\Entity\User {#1978 …}
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          +image: null
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          +body: """
            > **Trazodone (Desyrel)**\n
            \n
            [in relation to deep sleep promotion]
            """
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            date: 2023-12-07 02:04:23.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4188}
        +body: """
          As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
          \n
          I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
          """
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          date: 2023-12-07 03:20:45.0 +01:00
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      +root: App\Entity\EntryComment {#4188}
      +body: """
        > GHB\n
        \n
        It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
        """
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        date: 2023-12-07 03:40:04.0 +01:00
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        "@cheese_greater@lemmy.world"
        "@Drusas@kbin.social"
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        date: 2023-12-07 03:40:04.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4188}
    +body: "That's the one. Very effective for people like me, but not very available."
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      "@Drusas@kbin.social"
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      date: 2023-12-07 03:42:51.0 +01:00
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  }
  +root: App\Entity\EntryComment {#4188}
  +body: """
    I wish I could get diagnosed with narcolepsy so I could have it for that purpose, but it also sounds like an enormous bureaucratic headache and I also wouldn’t want someone to be able to take advantage of that knowledge/the rarity with which its prescribed to get you sucked into some bullshit sitch.\n
    \n
    Edit:\n
    \n
    > people like me [you]\n
    \n
    u narcoleptic dude?
    """
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Show voter details
123 DENIED edit
App\Entity\EntryComment {#4696
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      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
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      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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  +magazine: App\Entity\Magazine {#265}
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  +parent: App\Entity\EntryComment {#4643
    +user: App\Entity\User {#4359 …}
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    +magazine: App\Entity\Magazine {#265}
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    +parent: App\Entity\EntryComment {#4559
      +user: Proxies\__CG__\App\Entity\User {#1978 …}
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            > **Trazodone (Desyrel)**\n
            \n
            [in relation to deep sleep promotion]
            """
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        +body: """
          As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
          \n
          I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
          """
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      +body: """
        > GHB\n
        \n
        It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
        """
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        date: 2023-12-22 22:00:05.0 +01:00
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        date: 2023-12-07 03:40:04.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4188}
    +body: "That's the one. Very effective for people like me, but not very available."
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      date: 2023-12-07 03:42:51.0 +01:00
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  }
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  +body: """
    I wish I could get diagnosed with narcolepsy so I could have it for that purpose, but it also sounds like an enormous bureaucratic headache and I also wouldn’t want someone to be able to take advantage of that knowledge/the rarity with which its prescribed to get you sucked into some bullshit sitch.\n
    \n
    Edit:\n
    \n
    > people like me [you]\n
    \n
    u narcoleptic dude?
    """
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Show voter details
124 DENIED moderate
App\Entity\EntryComment {#4696
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      +title: "asklemmy"
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
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      \n
      [relevant keywords associated]
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            > **Trazodone (Desyrel)**\n
            \n
            [in relation to deep sleep promotion]
            """
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          As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
          \n
          I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
          """
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      +body: """
        > GHB\n
        \n
        It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
        """
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    +root: App\Entity\EntryComment {#4188}
    +body: "That's the one. Very effective for people like me, but not very available."
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  +body: """
    I wish I could get diagnosed with narcolepsy so I could have it for that purpose, but it also sounds like an enormous bureaucratic headache and I also wouldn’t want someone to be able to take advantage of that knowledge/the rarity with which its prescribed to get you sucked into some bullshit sitch.\n
    \n
    Edit:\n
    \n
    > people like me [you]\n
    \n
    u narcoleptic dude?
    """
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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              > **Trazodone (Desyrel)**\n
              \n
              [in relation to deep sleep promotion]
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              date: 2023-12-07 02:04:23.0 +01:00
            }
          }
          +root: App\Entity\EntryComment {#4188}
          +body: """
            As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
            \n
            I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
            """
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            date: 2023-12-07 03:20:45.0 +01:00
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        }
        +root: App\Entity\EntryComment {#4188}
        +body: """
          > GHB\n
          \n
          It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
          """
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          date: 2023-12-07 03:40:04.0 +01:00
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      }
      +root: App\Entity\EntryComment {#4188}
      +body: "That's the one. Very effective for people like me, but not very available."
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        date: 2023-12-07 03:42:51.0 +01:00
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    +body: """
      I wish I could get diagnosed with narcolepsy so I could have it for that purpose, but it also sounds like an enormous bureaucratic headache and I also wouldn’t want someone to be able to take advantage of that knowledge/the rarity with which its prescribed to get you sucked into some bullshit sitch.\n
      \n
      Edit:\n
      \n
      > people like me [you]\n
      \n
      u narcoleptic dude?
      """
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  +root: App\Entity\EntryComment {#4188}
  +body: "Yep"
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}
"Scheb\TwoFactorBundle\Security\Authorization\Voter\TwoFactorInProgressVoter"
ACCESS ABSTAIN
"App\Security\Voter\EntryCommentVoter"
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"App\Security\Voter\EntryVoter"
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ACCESS ABSTAIN
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ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
"App\Security\Voter\OAuth2UserConsentVoter"
ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
Show voter details
127 DENIED edit
App\Entity\EntryComment {#4751
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        A Fediverse community for open-ended, thought provoking questions\n
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        **Rules: (interactive)**\n
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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    +slug: "EXPERIMENTAL-What-are-your-hidden-gem-medications-drugs-substances-and-what-makes"
    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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            +body: """
              > **Trazodone (Desyrel)**\n
              \n
              [in relation to deep sleep promotion]
              """
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          +root: App\Entity\EntryComment {#4188}
          +body: """
            As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
            \n
            I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
            """
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        +root: App\Entity\EntryComment {#4188}
        +body: """
          > GHB\n
          \n
          It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
          """
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          date: 2023-12-07 03:40:04.0 +01:00
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      }
      +root: App\Entity\EntryComment {#4188}
      +body: "That's the one. Very effective for people like me, but not very available."
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      I wish I could get diagnosed with narcolepsy so I could have it for that purpose, but it also sounds like an enormous bureaucratic headache and I also wouldn’t want someone to be able to take advantage of that knowledge/the rarity with which its prescribed to get you sucked into some bullshit sitch.\n
      \n
      Edit:\n
      \n
      > people like me [you]\n
      \n
      u narcoleptic dude?
      """
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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              > **Trazodone (Desyrel)**\n
              \n
              [in relation to deep sleep promotion]
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          +root: App\Entity\EntryComment {#4188}
          +body: """
            As a user of this whose primary problem is frequent waking at night rather than falling asleep, I don't find it that helpful. It does help falling asleep, but it doesn't help one stay asleep.\n
            \n
            I've spoken with my sleep doctor about this and apparently basically the only thing that's good for helping somebody stay asleep as opposed to fall asleep is a common date rape drug so it's not commonly prescribed.
            """
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        +body: """
          > GHB\n
          \n
          It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
          """
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      +body: "That's the one. Very effective for people like me, but not very available."
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      I wish I could get diagnosed with narcolepsy so I could have it for that purpose, but it also sounds like an enormous bureaucratic headache and I also wouldn’t want someone to be able to take advantage of that knowledge/the rarity with which its prescribed to get you sucked into some bullshit sitch.\n
      \n
      Edit:\n
      \n
      > people like me [you]\n
      \n
      u narcoleptic dude?
      """
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        \n
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
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    > **D-Phenylalanine**\n
    \n
    [“endorphin reuptake inhibitor”?]
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Show voter details
131 DENIED edit
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        -----------------------------------------------------------------\n
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        \n
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        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        \n
        ---\n
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        \n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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    > **D-Phenylalanine**\n
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    [“endorphin reuptake inhibitor”?]
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132 DENIED moderate
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        -----------------------------------------------------------------\n
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        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        \n
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        \n
        ---\n
        \n
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        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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135 DENIED edit
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        \n
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        \n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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Show voter details
136 DENIED moderate
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        \n
        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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Show voter details
137 DENIED ROLE_USER
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Show voter details
138 DENIED moderate
App\Entity\EntryComment {#4236
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        \n
        ---\n
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        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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    > **Naltrexone**\n
    \n
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    \n
    I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
    """
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Show voter details
139 DENIED edit
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        \n
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        \n
        ---\n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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142 DENIED moderate
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        \n
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        ------------------------\n
        \n
        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
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        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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Show voter details
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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Show voter details
147 DENIED edit
App\Entity\EntryComment {#4575
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
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        ---\n
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        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
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        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
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        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
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        > **Naltrexone**\n
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        \n
        I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
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  +body: "I want to more rigorously experiment with it and other compulsive things I have challenges with, it seems the opioidergic system mediates `liking` and the compulsive attachment that flows from that so I’m curious to what extent its effect is extensible to other problematic habits, chemical or otherwise"
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Show voter details
148 DENIED moderate
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        \n
        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        > **Naltrexone**\n
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        \n
        I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        > **Naltrexone**\n
        \n
        I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.\n
        \n
        I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
        """
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    +body: "It's also used for opioid abuse disorders. Truly a miracle drug."
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  +body: "Can you expand on its actual use (like Vivitrol?) My understanding is its primarily used to treat alcoholism/AUD but maybe Vivitrol is used for both…"
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        \n
        ---\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        > **Naltrexone**\n
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        \n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
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      \n
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          > **Naltrexone**\n
          \n
          I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.\n
          \n
          I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
          """
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      +body: "It's also used for opioid abuse disorders. Truly a miracle drug."
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    +body: "Can you expand on its actual use (like Vivitrol?) My understanding is its primarily used to treat alcoholism/AUD but maybe Vivitrol is used for both…"
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    I can't comment on it personally, no, I've just heard and read about it some.\n
    \n
    This article, for example, mentions dosage guidelines: <https://www.mayoclinic.org/drugs-supplements/naltrexone-oral-route/proper-use/drg-20068408>
    """
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155 DENIED edit
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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          \n
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          \n
          I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
          """
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    I can't comment on it personally, no, I've just heard and read about it some.\n
    \n
    This article, for example, mentions dosage guidelines: <https://www.mayoclinic.org/drugs-supplements/naltrexone-oral-route/proper-use/drg-20068408>
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        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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          > **Naltrexone**\n
          \n
          I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.\n
          \n
          I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
          """
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    +body: "Can you expand on its actual use (like Vivitrol?) My understanding is its primarily used to treat alcoholism/AUD but maybe Vivitrol is used for both…"
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  +body: """
    I can't comment on it personally, no, I've just heard and read about it some.\n
    \n
    This article, for example, mentions dosage guidelines: <https://www.mayoclinic.org/drugs-supplements/naltrexone-oral-route/proper-use/drg-20068408>
    """
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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            > **Naltrexone**\n
            \n
            I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.\n
            \n
            I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
            """
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        +body: "It's also used for opioid abuse disorders. Truly a miracle drug."
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      +body: "Can you expand on its actual use (like Vivitrol?) My understanding is its primarily used to treat alcoholism/AUD but maybe Vivitrol is used for both…"
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      I can't comment on it personally, no, I've just heard and read about it some.\n
      \n
      This article, for example, mentions dosage guidelines: <https://www.mayoclinic.org/drugs-supplements/naltrexone-oral-route/proper-use/drg-20068408>
      """
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  +body: "[not snarky ;)] Pretty sure my understanding is correct, I’ve read about it before"
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        **Rules: (interactive)**\n
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      date: 2023-12-23 02:44:46.0 +01:00
    }
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      date: 2023-12-07 00:10:36.0 +01:00
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    +user: App\Entity\User {#4359 …}
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    +magazine: App\Entity\Magazine {#265}
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    +parent: App\Entity\EntryComment {#4591
      +user: Proxies\__CG__\App\Entity\User {#1978 …}
      +entry: App\Entity\Entry {#2400}
      +magazine: App\Entity\Magazine {#265}
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        +user: App\Entity\User {#4359 …}
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          +body: """
            > **Naltrexone**\n
            \n
            I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.\n
            \n
            I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
            """
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            date: 2023-12-07 02:00:29.0 +01:00
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        +body: "It's also used for opioid abuse disorders. Truly a miracle drug."
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      +root: App\Entity\EntryComment {#4236}
      +body: "Can you expand on its actual use (like Vivitrol?) My understanding is its primarily used to treat alcoholism/AUD but maybe Vivitrol is used for both…"
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    +body: """
      I can't comment on it personally, no, I've just heard and read about it some.\n
      \n
      This article, for example, mentions dosage guidelines: <https://www.mayoclinic.org/drugs-supplements/naltrexone-oral-route/proper-use/drg-20068408>
      """
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  +root: App\Entity\EntryComment {#4236}
  +body: "[not snarky ;)] Pretty sure my understanding is correct, I’ve read about it before"
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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            > **Naltrexone**\n
            \n
            I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.\n
            \n
            I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
            """
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        +body: "It's also used for opioid abuse disorders. Truly a miracle drug."
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      +body: "Can you expand on its actual use (like Vivitrol?) My understanding is its primarily used to treat alcoholism/AUD but maybe Vivitrol is used for both…"
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        date: 2023-12-07 03:42:07.0 +01:00
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    +root: App\Entity\EntryComment {#4236}
    +body: """
      I can't comment on it personally, no, I've just heard and read about it some.\n
      \n
      This article, for example, mentions dosage guidelines: <https://www.mayoclinic.org/drugs-supplements/naltrexone-oral-route/proper-use/drg-20068408>
      """
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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      > **Naltrexone**\n
      \n
      I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.\n
      \n
      I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
      """
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    Low Dose Naltrexone is amazing for all kinds of chronic pain and inflammation.\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/)
    """
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        \n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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      > **Naltrexone**\n
      \n
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      \n
      I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
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    Low Dose Naltrexone is amazing for all kinds of chronic pain and inflammation.\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/)
    """
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        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        \n
        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      > **Naltrexone**\n
      \n
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      \n
      I consider this the closest thing to a “cure” for drinking problems but it required discipline and it doesn’t prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
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    Low Dose Naltrexone is amazing for all kinds of chronic pain and inflammation.\n
    \n
    [www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/)
    """
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166 DENIED moderate
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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171 DENIED edit
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        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
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        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        ---\n
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172 DENIED moderate
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        \n
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        ------------------------\n
        \n
        ---\n
        \n
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        \n
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        \n
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        \n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        \n
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ACCESS ABSTAIN
Show voter details
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        \n
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        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        \n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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Show voter details
177 DENIED ROLE_USER
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Show voter details
178 DENIED moderate
App\Entity\EntryComment {#4445
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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  +root: App\Entity\EntryComment {#4283}
  +body: """
    Allowed for a sense of peace with my own mortality.\n
    \n
    ---\n
    \n
    Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
    \n
    (speaking as a user, not as a mod. Forgot lemmy always shows the icon)
    """
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Show voter details
179 DENIED edit
App\Entity\EntryComment {#4445
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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    Allowed for a sense of peace with my own mortality.\n
    \n
    ---\n
    \n
    Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
    \n
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Show voter details
180 DENIED moderate
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        \n
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        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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  +root: App\Entity\EntryComment {#4283}
  +body: """
    Allowed for a sense of peace with my own mortality.\n
    \n
    ---\n
    \n
    Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
    \n
    (speaking as a user, not as a mod. Forgot lemmy always shows the icon)
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Show voter details
181 DENIED ROLE_USER
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ACCESS ABSTAIN
Show voter details
182 DENIED moderate
App\Entity\EntryComment {#4524
  +user: Proxies\__CG__\App\Entity\User {#1978 …}
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    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
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      """
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      date: 2023-12-23 02:44:46.0 +01:00
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      date: 2023-12-07 00:10:36.0 +01:00
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  +magazine: App\Entity\Magazine {#265}
  +image: null
  +parent: App\Entity\EntryComment {#4445
    +user: Proxies\__CG__\App\Entity\User {#4446 …}
    +entry: App\Entity\Entry {#2400}
    +magazine: App\Entity\Magazine {#265}
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    +parent: App\Entity\EntryComment {#4283
      +user: Proxies\__CG__\App\Entity\User {#1978 …}
      +entry: App\Entity\Entry {#2400}
      +magazine: App\Entity\Magazine {#265}
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        "@cheese_greater@lemmy.world"
      ]
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        date: 2023-12-22 19:31:15.0 +01:00
      }
      +createdAt: DateTimeImmutable @1701909790 {#4264
        date: 2023-12-07 01:43:10.0 +01:00
      }
    }
    +root: App\Entity\EntryComment {#4283}
    +body: """
      Allowed for a sense of peace with my own mortality.\n
      \n
      ---\n
      \n
      Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
      \n
      (speaking as a user, not as a mod. Forgot lemmy always shows the icon)
      """
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      "@cheese_greater@lemmy.world"
    ]
    +children: Doctrine\ORM\PersistentCollection {#4447 …}
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    -bodyTs: "'allow':1 'alway':55 'better':36 'come':41 'empti':16 'forgot':53 'icon':58 'leav':15 'lemmi':54 'let':39 'like':18,23 'mod':52 'mortal':10 'necessari':13 'peac':6 'peopl':40 'read':29 'repli':17,27 'sens':4 'show':56 'speak':45 'think':33 'though':20 'user':48 'would':22"
    +ranking: 0
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    +apId: "https://sh.itjust.works/comment/6382135"
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      date: 2023-12-22 19:52:14.0 +01:00
    }
    +createdAt: DateTimeImmutable @1701911058 {#4444
      date: 2023-12-07 02:04:18.0 +01:00
    }
  }
  +root: App\Entity\EntryComment {#4283}
  +body: """
    - What was your particular orientation with that previously, like we’re all sort of shifty about death but I don’t think much about it (like before I was born, that doesn’t scare me so I kinda dont get the inverse of that)\n
    - do you have a condition that makes this all the more prescient or timely\n
    - any articulable messages you can share that encapsulate the experience we can try to glean from?
    """
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    date: 2023-12-07 02:56:04.0 +01:00
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    "@cheese_greater@lemmy.world"
    "@can@sh.itjust.works"
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    date: 2023-12-07 02:56:04.0 +01:00
  }
}
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"App\Security\Voter\EntryCommentVoter"
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"App\Security\Voter\EntryVoter"
ACCESS ABSTAIN
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ACCESS ABSTAIN
"App\Security\Voter\MessageThreadVoter"
ACCESS ABSTAIN
"App\Security\Voter\MessageVoter"
ACCESS ABSTAIN
"App\Security\Voter\NotificationVoter"
ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
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ACCESS ABSTAIN
Show voter details
183 DENIED edit
App\Entity\EntryComment {#4524
  +user: Proxies\__CG__\App\Entity\User {#1978 …}
  +entry: App\Entity\Entry {#2400
    +user: Proxies\__CG__\App\Entity\User {#1978 …}
    +magazine: App\Entity\Magazine {#265
      +icon: Proxies\__CG__\App\Entity\Image {#246 …}
      +name: "asklemmy@lemmy.world"
      +title: "asklemmy"
      +description: """
        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
        \n
        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
        \n
        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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    +title: "[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]"
    +url: null
    +body: """
      > **Generic name (Brand/street name)**\n
      \n
      Discussion paragraphs/submission\n
      \n
      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
      """
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        date: 2023-12-07 01:43:10.0 +01:00
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    }
    +root: App\Entity\EntryComment {#4283}
    +body: """
      Allowed for a sense of peace with my own mortality.\n
      \n
      ---\n
      \n
      Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
      \n
      (speaking as a user, not as a mod. Forgot lemmy always shows the icon)
      """
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      "@cheese_greater@lemmy.world"
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    - What was your particular orientation with that previously, like we’re all sort of shifty about death but I don’t think much about it (like before I was born, that doesn’t scare me so I kinda dont get the inverse of that)\n
    - do you have a condition that makes this all the more prescient or timely\n
    - any articulable messages you can share that encapsulate the experience we can try to glean from?
    """
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        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
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    +body: """
      Allowed for a sense of peace with my own mortality.\n
      \n
      ---\n
      \n
      Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
      \n
      (speaking as a user, not as a mod. Forgot lemmy always shows the icon)
      """
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    - What was your particular orientation with that previously, like we’re all sort of shifty about death but I don’t think much about it (like before I was born, that doesn’t scare me so I kinda dont get the inverse of that)\n
    - do you have a condition that makes this all the more prescient or timely\n
    - any articulable messages you can share that encapsulate the experience we can try to glean from?
    """
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185 DENIED ROLE_USER
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
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        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      ---\n
      \n
      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
      \n
      [relevant keywords associated]
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      date: 2023-12-23 02:44:46.0 +01:00
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      date: 2023-12-07 00:10:36.0 +01:00
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    +magazine: App\Entity\Magazine {#265}
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    +parent: App\Entity\EntryComment {#4445
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          date: 2023-12-07 01:43:10.0 +01:00
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      +root: App\Entity\EntryComment {#4283}
      +body: """
        Allowed for a sense of peace with my own mortality.\n
        \n
        ---\n
        \n
        Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
        \n
        (speaking as a user, not as a mod. Forgot lemmy always shows the icon)
        """
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    +body: """
      - What was your particular orientation with that previously, like we’re all sort of shifty about death but I don’t think much about it (like before I was born, that doesn’t scare me so I kinda dont get the inverse of that)\n
      - do you have a condition that makes this all the more prescient or timely\n
      - any articulable messages you can share that encapsulate the experience we can try to glean from?
      """
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  +root: App\Entity\EntryComment {#4283}
  +body: """
    - roughly the same with added suicidal ideation\n
    - no\n
    - no
    """
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}
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Show voter details
187 DENIED edit
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        A Fediverse community for open-ended, thought provoking questions\n
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
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        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
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        Partnered Communities:\n
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        [Tech Support](/c/techsupport@lemmy.world)\n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      Discussion paragraphs/submission\n
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      *If you are curious about a specific substance but can’t answer, please follow this format—\n
      \n
      > **Generic name (Brand/street name)**\n
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          date: 2023-12-07 01:43:10.0 +01:00
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      +body: """
        Allowed for a sense of peace with my own mortality.\n
        \n
        ---\n
        \n
        Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
        \n
        (speaking as a user, not as a mod. Forgot lemmy always shows the icon)
        """
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        date: 2023-12-07 02:04:18.0 +01:00
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      - What was your particular orientation with that previously, like we’re all sort of shifty about death but I don’t think much about it (like before I was born, that doesn’t scare me so I kinda dont get the inverse of that)\n
      - do you have a condition that makes this all the more prescient or timely\n
      - any articulable messages you can share that encapsulate the experience we can try to glean from?
      """
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      date: 2023-12-07 02:56:04.0 +01:00
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  }
  +root: App\Entity\EntryComment {#4283}
  +body: """
    - roughly the same with added suicidal ideation\n
    - no\n
    - no
    """
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        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
        ---\n
        \n
        2) All posts must end with a '?'This is sort of like Jeopardy. Please phrase all post titles in the form of a proper question ending with ?\n
        \n
        ---\n
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        3) No spamPlease do not flood the community with nonsense. Actual suspected spammers will be banned on site. No astroturfing.\n
        \n
        ---\n
        \n
        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
        \n
        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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      +body: """
        Allowed for a sense of peace with my own mortality.\n
        \n
        ---\n
        \n
        Is it necessary to leave empty replies like this though? I would like to have more replies to read too but I think it’s better to just let people come up with them.\n
        \n
        (speaking as a user, not as a mod. Forgot lemmy always shows the icon)
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    +body: """
      - What was your particular orientation with that previously, like we’re all sort of shifty about death but I don’t think much about it (like before I was born, that doesn’t scare me so I kinda dont get the inverse of that)\n
      - do you have a condition that makes this all the more prescient or timely\n
      - any articulable messages you can share that encapsulate the experience we can try to glean from?
      """
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  }
  +root: App\Entity\EntryComment {#4283}
  +body: """
    - roughly the same with added suicidal ideation\n
    - no\n
    - no
    """
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Show voter details
189 DENIED ROLE_USER
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Show voter details
190 DENIED moderate
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        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        \n
        ---\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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192 DENIED moderate
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        -----------------------------------------------------------------\n
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        \n
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        ------------------------\n
        \n
        ---\n
        \n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        \n
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        \n
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        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
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        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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194 DENIED moderate
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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199 DENIED edit
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        \n
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        ------------------------\n
        \n
        ---\n
        \n
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        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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Show voter details
200 DENIED moderate
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        ---\n
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        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
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        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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    > **Baclofen**\n
    \n
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Show voter details
201 DENIED ROLE_USER
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202 DENIED moderate
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        \n
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        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        5) This is not a support community.It is not a place for ‘how do I?’, type questions. If you have any questions regarding the site itself or would like to report a community, please direct them to [Lemmy.world Support](https://lemmy.world/c/support) or email info@lemmy.world. For other questions check our partnered communities list, or use the search function.\n
        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
        ----------------------\n
        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
        \n
        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
        ---\n
        \n
        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
        \n
        ---\n
        \n
        ![](https://img.shields.io/lemmy/asklemmy%40lemmy.world?logo=lemmy&label=Total%20Subscribers)
        """
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    Rapidly cures migraines.
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203 DENIED edit
App\Entity\EntryComment {#4346
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    +magazine: App\Entity\Magazine {#265
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        A Fediverse community for open-ended, thought provoking questions\n
        -----------------------------------------------------------------\n
        \n
        ---\n
        \n
        **Rules: (interactive)**\n
        ------------------------\n
        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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        \n
        ---\n
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        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
        \n
        [Reddit](/c/reddit@lemmy.world)\n
        \n
        [Jokes](/c/jokes@lemmy.world)\n
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        [Ask Ouija](/c/askouija@lemmy.world)\n
        \n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
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        \n
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        ------------------------\n
        \n
        ---\n
        \n
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        \n
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        \n
        Partnered Communities:\n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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        ---\n
        \n
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        \n
        ---\n
        \n
        1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
        \n
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        \n
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        \n
        ---\n
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        4) NSFW is okay, within reasonJust remember to tag posts with either a content warning or a [NSFW] tag. Overtly sexual posts are not allowed, please direct them to either [!asklemmyafterdark@lemmy.world](https://lemmy.world/c/asklemmyafterdark) or [!asklemmynsfw@lemmynsfw.com](https://lemmynsfw.com/c/asklemmynsfw). NSFW comments should be restricted to posts tagged [NSFW].\n
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        \n
        ---\n
        \n
        Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
        \n
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        \n
        [Tech Support](/c/techsupport@lemmy.world)\n
        \n
        [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
        \n
        [You Should Know](/c/youshouldknow@lemmy.world)\n
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Show voter details
213 DENIED edit
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    -----------------------------------------------------------------\n
    \n
    ---\n
    \n
    **Rules: (interactive)**\n
    ------------------------\n
    \n
    ---\n
    \n
    1) Be nice and; have funDoxxing, trolling, sealioning, racism, and toxicity are not welcomed in AskLemmy. Remember what your mother said: if you can’t say something nice, don’t say anything at all. In addition, the site-wide Lemmy.world terms of service also apply here. [Please familiarize yourself with them](https://legal.lemmy.world/tos/)\n
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    ---\n
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    \n
    ---\n
    \n
    Reminder: The [terms of service](https://legal.lemmy.world/tos/) apply here too.\n
    \n
    Partnered Communities:\n
    ----------------------\n
    \n
    [Tech Support](/c/techsupport@lemmy.world)\n
    \n
    [No Stupid Questions](/c/nostupidquestions@lemmy.world)\n
    \n
    [You Should Know](/c/youshouldknow@lemmy.world)\n
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    \n
    Logo design credit goes to: [tubbadu](/u/tubbadu@lemmy.world)\n
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