In English, lack of second-person plural, aside from a dozen regionalisms: y’all, yinz, youse, etc.
No distinction between inclusive & exclusive ‘we’: if I say “we’ve got to go now”, do I expect you to come?
Unnecessarily generated pronouns. I know ‘they/them’ has been used for individuals for ages, but I still find it awkward. I wish we just used one set of ungendered pronouns for every specific person.