It might not help you as it seems you might be in the US, but I regularly donate to MIND (a UK mental health charity), mermaids UK (A UK trans youth charity), Stonewall, and Greenpeace. I think they’re all awesome.
I also support the Awesome Socks Club, which isn’t really a charity donation but they’re donating 100% of profits to various charities, they said they’re trying to beat Paul Newman’s company’s charitable contributions which is a huge effort, it supports independent artists, and you get cool socks to top it off. (www.good.store)