Not for AdSense ads, like what YouTube uses. Click-Through Rate (CTR) is only used to determine how much of a cut Google gives to the ad hosts, the advertisers just bid for the spots. The advertisers can see the CTR metrics, and so they might be willing to bid more, but that’s not guaranteed.
So google makes money either way, and the advertisers spend money either way. The only difference is that your favorite websites and youtubers get paid too.