I found it really hard to believe people would care that much about karma to the point that I never really believed most accusations of “karmawhore.” Because who would care that much? You just don’t like this kind of content that got popular. I totally believed a few individuals would optimize their posts and comments for the most upvotes, but not nearly enough to justify how often I heard that accusation flung around. Sure, it feels nice to see that other people like your comment. And it’s nice to have the voting system so incorrect information, spam, and trolls get downvoted and thus hidden; while theoretically the helpful and insightful comments rise to the top (and at least in the subs I used, this is how it also worked in practice, although judging by all the complaining about Reddit I see here it wasn’t true for a lot of other peoples’s subs). And of course you will want to get your karma past the common thresholds for not getting your post removed for being a new, low-karma account. But otherwise, what does it really matter?