The settings themselves vary wildly, and technically the books occur before, during, and after the present. The level of technology varies wildly.
The one thing in common is the examination of the content of the character of the "human" being, and how we are the same or different, adapt or don't, expand or hide.
It's truly masterful work that, yes has cool gizmos and concepts but worries more about how the gizmos make you feel.