That’s pretty much the point. (ie - stuff I need won’t work in wine or won’t work at a HW level).
Wine is fun, but are a growing number of features that are not supported and likely never will be. (by way of example - NI Access 2 installer uses UAC calls. Not workable.
It becomes a game of whackamole trying to find workaround after workaround (and a coin toss as to whether or not one actually exists…)