To add to this, another viable path is using Nix, the package manager, on its own. That way you can get Home Manager to manage your applications and dotfiles independently of your base system, as long as you are able to install Nix.
It’s my general workflow, run Determinate Nix Installer, install Home Manager, clone my config and I’m off to the races. Been sharing that config between Debian, Ubuntu on WSL and Bazzite for a while and it’s served me well so far.