Bitwig and Blender work great on Linux, as well as most games. MS Office and the proprietary apps will need a separate Windows install. Wine is a compatibility layer that essentially translates the Windows files into something that your Linux OS can use. It works great for some things, like games, but isnt recommended/doesn’t work for others, like Office or Adobe suite. Personally I’d recommend finding the alternatives for the programs you need on Windows and trying them out, while keeping the original programs in your Windows install. You can get used to the workflow of the new programs and decide if switching is a viable thing for you. And if not, hey now you’re comfortable with another set of programs just in case you need them in the future.