For me, it’s not the DAW (Reaper works fine), but this is not the case for every DAW and it must be recognized that switching DAWs is non-trivial (nor should it be expected). In my case, it’s the HW. I can likely get my interface to run (unsupported) but my Maschine is a non-starter. Yes - I know there are a few drivers for similar HW around written by clever folk who’ve done reverse engineering, but it only covers a few minor use cases and is, at best a science experiment and not something one should ever depend on even if it did work.
SW is a problem too - yes most plugins can be coaxed into working, but certainly not all. Add to that the underlying tech is usually wine, and it’s a perpetual game of whackamole to maybe get the stuff you paid for to run.
The folks writing these bridging tools are not too blame - it’s brilliant, wonderful work. Fundamentally, it’s an act of good will that one can’t rely afford to fully depend on if it even does work. I love FOSS, but it’s not everything - I certainly don’t expect a free ride, but I do want the option to pay to run what I want.
The issue is the HW and SW manufacturers - they need a critical mass of potential users to be bothered to commit to developing for Linux. My hope is that as user bases grow (in places like India) the cost/benefit analysis shifts.