So I decided while playing Fallout 4 (around the time it came out) that I was going to try to break this habit, because it meant I never got to use any of the cool shit.
I made this decision while retaking the castle, fighting the queen crab thing. I used all the mini nukes I had on it.
Those who have played the game knows what happens next... after killing the queen, the king emerges. Way bigger, way harder to kill.
I've been a hardcore no exceptions hoarder ever since