The problem I’ve found is that the services will query indexers and that not all of the trackers allow you to use multiple IPs. This is where I found it easier to make all outbound requests go through the VPN so I didn’t get in trouble. It’s also why I have the Firefox container set up inside the network with it exposed over the local network as a VNC session. So I can browse the sites while maintaining a single IP.
I do have qbittorrent set up with a kill switch on the VPN interface managed by Gluetun.