Do these files come pre-patched or are they clean? If they’re clean, re-install, disconnect from the internet, and see if it is able to open normally. That way we’d then be able to isolate the issue to the patch painter.
If they come pre-patched, then aside from trying on another system or in a VM, i’m not too sure how this would be fixed. Have a look at the readme/description of wherever you downloaded it from, there could be extra steps needed that haven’t been done yet. If the collection came inside an ISO file, mount it instead of extracting it, as Windows Defender can’t delete things from ISOs AFAIK. If you extracted, then maybe something important was deleted by Windows defender
Also, at your own risk, disable Windows defender, it may delete the patched Adobe DLLs off your system the second it sees an executable loading them