I am happy with my simple docker-compose setup - one root folder with one subfolder per project containing the compose file and any configuration mounted into the container. Traefik automatically exposes all services I want under a well-known URL using a single line in each compose file. Watchtower updates the containers.
This has been running stable for over two years with probably 2-3 reboots in between. If my current NUC ever breaks I’ll set it up again using Podman instead of Docker, but aside from that I couldn’t be happier!