What was your particular orientation with that previously, like we’re all sort of shifty about death but I don’t think much about it (like before I was born, that doesn’t scare me so I kinda dont get the inverse of that)
do you have a condition that makes this all the more prescient or timely
any articulable messages you can share that encapsulate the experience we can try to glean from?
Fascinating medication that I have found to annihilate anxiety (excellent anxiolytic) and promote social cohesion/sociabillity/oversharing beware. Takes the edge of stimulants as well
Almost like a pharmaceutical slightly sedative-leaning version of ecstasy but obviously quite distinct pharmacologically and not a replacement for same.
It really is too bad people misuse it like that. I’ve heard the sleep is insanely deep and refreshing and its a damn shame you’re automatically sketch if you want that for your own benefit
I wish I could get diagnosed with narcolepsy so I could have it for that purpose, but it also sounds like an enormous bureaucratic headache and I also wouldn’t want someone to be able to take advantage of that knowledge/the rarity with which its prescribed to get you sucked into some bullshit sitch.
Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it
I want to more rigorously experiment with it and other compulsive things I have challenges with, it seems the opioidergic system mediates liking and the compulsive attachment that flows from that so I’m curious to what extent its effect is extensible to other problematic habits, chemical or otherwise
I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?
Thanks and no rush, I’ll listen to that article tomorrow :)
It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that
From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.
Yeah, ask about baclofen, its famously advocated by a French dr who struggled to find a proper treatment for his alcoholism until he arrived on baclofen. End of My Addiction is the title.
I used it as an adjuvant treatment along with naltrexone and careful timing in terms of the actual drinking that was required to make the naltrexone effective in addressing the neurochemical basis for much of the compulsion from alcohol.
Thats why I’m doing this thread, its a labor of love and curiosity but I’m intrigued to hear everyone dish freely about such a mundanely “taboo” subject
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[EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]
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