It also uses the Red Hat RPM package format and a different package manager. But it just amounts to a few different commands to learn if you manage packages on the command line.
I have no knowledge about or experience with immutable distros, but I’ve been maining the Fedora KDE spin on my laptop for several major releases now and so far have found no reason to switch away from it. The Plasma Wayland session has been solid from the beginning and everything has just worked.