Orbital fatalities so far are just Soyuz 1, Soyuz 11, STS-51-L, and STS-107. We are still a bit early, but Space exploration has been surprisingly safe so far.
It’s been gradually ramping up with things like the Inspiration4 and Axiom missions, but still relatively slow. Yuri Gagarin’s historic flight is further from today than the Wright Brothers’ flight is from Yuri Gagarin’s flight.
Ponies aboard the ship 'Terra Nova' during an Antarctic expedition, 1910 (lemmy.world)