Insignificant in the wider picture, maybe. But as you imply we have little to no control over that. All we can influence is our own actions, and hope that will be enough. The problem with the defeatist attitude that so often surrounds any discourse regarding, for example, climate change is that by declaring success impossible before you even try, all you do is guarantee failure.
All one need do is chose what changes one wishes to make and then make them to the best of one’s abilities. That’s it. If you can look yourself in the eye and say ‘I did all I could. I did my best’ then you have succeeded. Will it achieve everything we want it to? Maybe not, but it’ll achieve 100% more than not trying. Ultimately we all have a responsibility to do what we can. So I argue we should all try and do just that and be content that we did our best, because I will not except defeat. How about you?