Have a prednisone horror story as well, couldn’t taper off without severe withdrawal and it led to me needing emergency surgery after an ulcer rupture, which led to my resections and eventual clinical remission. Did they actually test you for antibodies against infliximab or is that just a general safety precaution they’re following? I was off it for a couple months because of coverage issues but they had no problem starting me on it again and following normal infusion protocols. I think I’ve been on it for 15 years now. My GI specialist was one of the first in the area to start with the “top-down” approach for treatment around when I had my surgeries. Etrolizumab looked promising but the Phase III failed to deliver unfortunately, was hoping for that one if I had issues with infliximab.