It’s not just car-centric Euclidean zoning and suburban sprawl.
The US also builds really dangerous stroads that you don’t really see in most other countries.
5+ lanes of 55mph traffic next to a sidewalk and tons of driveways for businesses is inherently unsafe.
It’s also interesting to note that the biggest spike in fatalities was during the pandemic.
The best explanation I’ve heard is that bumper-to-bumper rush hour traffic essentially disappeared with the switch to WFH during the pandemic. Streets artificially looked safer pre-pandemic due to drivers getting stuck in traffic at peak periods. The pandemic just revealed how inherently unsafe American stroads are.