Pythons are pretty chill snakes overall tbh. If you’re careful, handle them frequently, and make sure they’re comfortable in their environment they won’t do anything. It all comes down to owner handling.
They also aren’t that stupid and won’t (usually) try to attack anything that’s too big for them to eat, except out of fear. Because thats a waste of energy. And she is very much too big for him to get his mouth around to digest. So no, she isn’t going to die.