In general, consider setting up any kind of rollback functionality; this will enable you to get right back to action without any downtime when you’re time-restricted. This can be achieved by configuring your system with (GRUB-)Btrfs+TImeshift/Snapper. Please bear in mind that it’s likely that you have to come back to solve it eventually, though*. (Perhaps it’s worth thinking about what can be done to ensure that you don’t end up with a broken system in the first place. cough‘immutable’distrocough)
If you feel absolutely overwhelmed by the amount of choice, then you should probably consider the bold ones; not because I think they’re necessarily better but:
openSUSE’s offerings are generally speaking very polished, therefore being highly suitable to replace Linux Mint or Ubuntu. It’s its own thing though, therefore you might not be able to access packages that are exclusively found in Debian’s/Ubuntu’s repos (though Distrobox solves that trivially). Tumbleweed if you like rolling release, Slowroll if you prefer updates only once every 1-2 months and finally Leap if you lean more towards Stable/LTS releases.
siduction for being based on Debian; but it’s strictly on the Unstable(/Sid) branch.
SpiralLinux for being based on Debian; this one -however- has proper support for switching branches.
Vanilla OS for being based on Debian; this one is very ambitious. But, because it’s an ‘immutable’ distro, it might require the biggest changes to your workflow.
nvidia drivers are absent
While any of the aforementioned distros do a decent job at ‘supporting’ Nvidia, perhaps you might be best off with uBlue’s Nvidia images. As these are images relying on the same technology that Fedora’s immutable distros do, rollback functionality and all the other good stuff we’ve come to love -like automatic upgrades in the background- are present as well. In case you’re interested to know how these actually provide improved Nvidia support:
“We’ve slipstreamed the Nvidia drivers right onto the operating system image. Steps that once took place on your local laptop are now done in a continuous integration system in GitHub. Once they are complete, the system stamps out an image which then makes its way to your PC.
No more building drivers on your laptop, dealing with signing, akmods, third party repo conflicts, or any of that. We’ve fully automated it so that if there’s an issue, we fix it in GitHub, for everyone.
But it’s not just installation and configuration: We provide Nvidia driver versions 525, 520, and 470 for each of these. You can atomically switch between any of these, so if your driver worked perfectly on a certain day and you find a regression you just rebase to that image.
Or switch to another desktop entirely.
No other desktop Linux does this, and we’re just getting started.”