re: Skyrim, could just be that some SKSE mod you’re using needs some newer .net runtime or similar
could also be not enough vram (even if you have enough ram wine/proton could have it’s vram allowance set too low)
If you don’t already have one get a crashlogger, for SkyrimSE 1.5.97 I would recommend .NET Script Framework (and use SSE Engine Fixes skse64 preloader instead of DLL Plugin Loader)
If you already knew about all this and still having issues then don’t mind me