ext4 certainly has its place, it’s a fine default file system, there’s really no problems with it.
But others, like ZFS and BTRFS, have features that you may want to use, but ext4 doesn’t do: fs snapshots, data compression, built in encryption (to a degree, usually only happening for data and some of the metadata, so LUKS is often better IMHO), checking for bitrot and restoring it when possible (whether it is depends on your config), quotas per user group or project, spanning multiple disks like with RAID but safer (to a degree), and others.