If you can figure out how to get the remote open, you’ll probably find that the buttons are all part of the same flexible rubbery insert (unless it’s 10+ years old). Put a little tape on the bottoms of the ones causing you problems. The insulation should keep them from working, and it’s 100% reversible if you ever do find a use for them.
If it’s one of the older, more expensive remotes with individual switches, then, yeah, pliers and superglue. 😅