“Working well” is relative. You can make Nvidia work, but there are some caveats. Currently, there’s driver 535 and 545, and both have different quirks. Neither works particularly well with Wayland, certain applications can flicker when they need longer to draw than the display’s refresh rate.
So, when I tried with the 3080, I eventually gave up and used X11. X11 has a technical limitation though, and it prevents VRR to work with multiple displays. That’s because X11 combines all displays to a single virtual “screen”, so a full screen application on one display can’t set the refresh rate of that display independently. This isn’t a problem with single monitor setups though.
As I tested Baldur’s Gate 3, I found that choosing Vulkan in the launcher resulted in about half the performance compared to Windows, and DirectX 11 (which ironically gets translated to Vulkan by DXVK) had graphical glitches like black boxes instead of houses etc.
Knowing all that and if you’re willing to experiment with driver versions, it’s not that horrible, it’s just not as straightforward as AMD Radeon on Linux (or Nvidia on Windows for that matter).