EDIT: I wanted a Noctua but with my two big GPUs, there is no space for a Noctua… and depends on which motherboard also includes water cooling tubes already built-in.
Much more space on CPU (at least you see the RAM and other components), yeah, depends on how you built it. The PC can “breath”. When I said “you need a lot of space” I mean on the CPU, if your RAM and 2 GPU is all near there… all the heat gets concentrated.