What exactly does ‘should’ mean here? Should in order to achieve what?
If you want to know what the word means at the expense of interrupting the flow, then yes.
If you want to stay with the flow, then no.
That said, it is so simple in almost all situations these days to look a definition up that I almost always do on the odd occasions that I find a word I don’t know. And the more you do, the less you will need to in future.
If you're reading something and you don't understand a word, should you stop and research it or should you keep reading the whole thing first?