Like i give a fuck what cools best. I want my system to look awesome and the AIO sure looks better imo. At the end of the day: build the PC that makes you happy.
I feel like these two are additive. A script could present a vulnerability without being an ad (and thus be on the blocking list on adblock) could it not? So feel like to accept the least amount of scripts is the way to go. However i understand the annoyance because sometimes i just want to visit a page without going through every single one of the many scripts. What i have started doing is to use a different browser from my default one if this situation arises. This browser is only having adblock as addons so when a page does not work and i dont want to fiddle with the setting i just visit via the other browser. Not an ideal solution, i know, but i think its better than getting rid of NoScript.
I would love to hear better solutions though because i admit i am not an expert in anything.
Now hear me out: Get yourself a dakimakura. With depression you will spend more time in bed than you like anyways and this way you alteast got something nice and plush to cuddle with in bed. It sounds bad but it feels good, believe me. If you feel like seeing people again but are embaressed you can always hide it in the closet. Or go with a neutral cover and say it helps sleeping on the side.