If it can be proven to be "self dealing" aka your NGO, charity, or non profit purchases or accepts a tax deductible donation of say, a portrait of you, from you or one of your businesses for hypothetically, 100 million dollars, then you may, if you did something particularly odious such as say, run for president. Then you might lose the legal ability to run that sort of organization.
Not unless you do it outside a golden palace that abstracts your money into vouchers and chips.
But generally wealthy people make more gambles in business, partnership, accountability, other people's lives and social welfare, and the general stability of the world.
Like say becoming an arms dealer then paying the cost of a F-150 economy package to a couple senators and having them spend their endless war chests with no audits or oversight on some missiles to kill some goat farmers or something.
Or creating a pesticide with the upside of remaining active in soil for 4 or 5 centuries (and recycling in the human liver for up to a year after exposure) and having it produced in an impoverished southern town and then exported to French Polynesia so they can continue to grow cloned banana trees.
Or like taking doctors on nice yacht lunches and golf trips and telling them yes you really have developed a non addictive opioid.
I believe this is right after psychotic mommy issues superman murders a protestor with his Lazer vision and is surprised to be cheered for it by his supporters.