I’m very aware of the history of race science. Tell me what that has to do with physics, chemistry, astronomy, geology, and exactly why we should “require many barriers to science” today because the already thoroughly refuted race science existed? Because that is what the other commenter stated.
I’m sorry, is there something inherent in communism that suggests we should be anti-intellectual because racism exists? There are valid criticisms of racism in all aspects of our society, yes including academia. But “the dominant source of academic science is race science” therefore we need barriers to all science ain’t it
Thank you for reminding me to reach out to the Boost app dev to ask why I’m still seeing lemmygrad dumbass trash takes even though I blocked the grad the day I downloaded the app.
Lord, you and I must have been on different forms of reddit if you think the users over here are more overly assured and aggressive than reddit. Personally, I find most conversations so much more productive here.
Thanks for the well wishes. Also last year I participated in a clinical trial with this same team at the Brigham. The drug trialed there is called bocidelpar. It targets a mitochondrial receptor called PPAR-δ. We’re still waiting on the results of that trial to be released and it’s probably a good 3-5 years away from FDA approval in the US if all goes well. So here’s hoping for the best
So, the team that I’m seeing at Brigham & Women’s in Boston has a testing protocol called invasive cardiopulmonary exercise testing or iCPET, which involves putting a tube into a large vein in the neck, putting a heart catheterization through that, then putting a tube in an artery in the wrist. This allows monitoring and comparison of blood pressures inside the heart vs. outside the heart as well as comparison sampling of arterial blood vs. venous blood. In addition to this, they apply EKG heart monitoring and respiratory monitoring via a gadget you hold in your mouth and breathe through. With all this insanity in place, they put you on an exercise bike until you can’t stand it anymore.
What they find on this test is a combination of two things. First, the pressures inside the ventricles of the heart do not increase in response to increased physical activity the way that they should. “Low ventricular filling pressure caused by preload failure.” And second, the DEoxygenated blood returning to the heart has too much oxygen in it, indicating poor oxygen uptake on a cellular level, which they hypothesize is caused by mitochondrial problems.
The treatments include a drug called pyridostygmine, which increases acetylcholine neurotransmitter to increase autonomic nervous system response to physical activity (and therefore increase blood return to the heart). Or a drug called midodrine, which also supports blood pressure. Plus supplements to support mitochondrial function like CoQ10, creatine, and ALCAR.
I’m not cured and back to where I was prior to getting sick by any means, but I’m able to hold down a full time job, which prior to treatment I most definitely would not have been able to.
I’ve eaten at a 2 star Michelin restaurant. It was definitely theater and not a meal. The Menu is one of the best dark humor movies I’ve ever seen because it’s honestly not that far off lol
The more critical a situation is, the slower and more deliberately I move because mistakes waste time. We have a saying “slow is smooth and smooth is fast.” Validate and verify everything.
Validate monitoring: Is that heart rate or blood pressure really that high or low? Don’t just believe the computer monitor, grab a stethoscope and listen to the chest, grab a manual BP and double check. Does the appearance of the patient correlate with what the numbers say? (ie: does the human being look as sick as those numbers imply?)
Verify interventions: I think to myself “clamp that line, unclamp this line, attach that device, open this lid, engage the safety on this needle” with every action. Repeat out loud to colleagues in the room what you’re going to do, then after you’ve done it, say out loud again what you just did. Especially if you do something out of the ordinary or unexpected.
Like yesterday, we had a patient who suddenly had symptoms of a myocardial infarction (“heart attack”), had some concerning findings on EKG, so we were trying to draw blood labs urgently and having such a hard time that one of the doctors even had a needle trying to help us. I was leaving the room to get more supplies and I took a bunch of trash with me, so I took the 3 seconds to count what I was holding and said out loud, “There are no sharps in the bed, you guys, I have them all,” because we were just laying discarded needles (with safeties engaged) on top of the bed blanket.
Two minutes is an eternity when life is on the line. Slow down, don’t hurry, do things on purpose, double check what you’re doing. That’s a lesson applicable to a surprising number of life situations
Yeah we had a lot of that kind of thing, where you get a kid who starts helping provide for family finances when they hit age 18 (some as minors), but it was never like a parents “charging them rent” kinda situation. And I’ve certainly never seen that kind of behavior encouraged in any way. Anyone who charged their kids rent would be considered real assholes. But I’m from Appalachia and Midwestern social circles.
No they’re not lol. It’s considered very weird to charge your own child rent. Those stories make headlines because even Americans find them shocking. My sister lived with my parents until she was 27 and they never charged her a dime. I could move back in with them tomorrow and they wouldn’t charge me either. This is the norm in American families