Instead of guessing, looking at the log might help. Launch the game with PROTON_LOG=1 %command% set in “Set Launch Options” setting in the game properties. The log file will appear on your home directory.
Don’t use the official Reddit app. Instead, grab the last release apk of Sync for Reddit from apkmirror, then use revanced manager to patch it with your own api key (and probably patched out the ads while you’re at it).
The one that bother me the most about Wayland is the future of *BSD desktop. Can you run Wayland on NetBSD/FreeBSD yet? Also, currently you can run x server on Mac so you can run X11 apps remotely for example. Is there any attempt to make waypipe work on MacOS?
It’s a long shot, but sometimes when I have issues with proton which I can’t figure out, switching from Wayland to X11 (or vice versa) magically fixed it.