asklemmy

This magazine is from a federated server and may be incomplete. Browse more on the original instance.

CarlsIII, in What do you call this place?

It’s that scene from the Shining with the twins, being played by a couple of those giant robots I keep seeing on the hills while driving on I-5

paddirn, in What do you call this place?

The Dead Zone

Soku, in What country are you using lemmy from?

UK, London

cashews_best_nut,

London

A shit’ole full o’ poncey cunts.

t0fr, in What country are you using lemmy from?
@t0fr@lemmy.ca avatar

Canada

sirxdaemon, in What country are you using lemmy from?
@sirxdaemon@lemmy.ca avatar

Country is fine. City too.

Soku,

Echolalia?

can,

GPS coordinates are acceptable.

Pons_Aelius,

0.000000, 0.000000

sasquash471, in What country are you using lemmy from?

Liechtenstein

TomSelleck, in What country are you using lemmy from?

AZ

Alkaseltzer028, in What country are you using lemmy from?

Curaçao

idunnololz, in What gifts are you getting for your friends and family members?
@idunnololz@lemmy.world avatar

I’m getting my mom a rowing machine because she wants one to help her exercise more. I’m getting my SO a Chromebook because his old one is like 7 years old now.

BigDanishGuy, in What are your "poor person" money life hacks?

Pay cash for groceries. At the start of each pay period, withdraw your grocery budget in cash for that period.

Make sure that you get bills that exactly covers a day each.

Every morning pull out a bill from your drawer, whatever you have in your wallet is what you have for groceries.

effward,
@effward@lemmy.world avatar

You must not live in the typical American city, where it’s completely impractical to go grocery shopping that often.

BigDanishGuy, (edited )

Nope, as per my username I live in a place where infrastructure was developed before the car.

Update: you don’t need to purchase groceries daily. That would be more expensive, you put the money aside for later. The trick is that you don’t spend money that should cover expenses next week, that way you can more closely monitor your spending.

effward, (edited )
@effward@lemmy.world avatar

Yeah, I figured.

I didn’t mean it as a critique of what you were saying, and certainly not as an insult to you, but rather as a disappointed critique of American city layouts.

31337, in What are your "poor person" money life hacks?

I once met some hippie-like people who fed themselves exclusively by dumpster diving. Not sure where they got their stuff, but they had a lot of high-end foods (cheese wheels, expensive meats, not-so-fresh produce, etc). They lived in busses, vans, RVs and stuff like that. They didn’t have jobs; not sure how they got money for things like clothes; odd-jobs I guess.

Less extreme “hacks”: Goodwill, or Ross/Marshalls if you’re feeling fancy. Ebay/Craigslist/Offer-up (need to be careful about getting ripped-off, and Ebay isn’t as cheap as it used to be). Buy, cook, and eat mostly cheap staples (rice, beans, pasta, etc). If eating meat, you can use it sparingly by cooking recipes that comprise mostly of cheap staples. Budget Bytes has decent recipes. Unfortunately, most people’s biggest expense is housing, and there aren’t many “hacks” for that. Maybe, get a work-from-home job and move to Wyoming or something

shinigamiookamiryuu, in What would be some of your top choices of things to see if you were the size of an ant?

Being the size of an ant would make riding small helium balloons fun.

DesertCreosote, (edited ) in What are the best e-readers on the market?

I’m going to jump on the Kobo train along with everyone else. I have a Kobo Libra H2O that I really love. I had a couple Kindles before deciding that I really didn’t want to stick with an Amazon product, and chose Kobo because of its integrations with Overdrive. It’s really nice to be able to check out a book from the library directly on my e-reader.

The screen is bright when it needs to be, but dims down quite nicely. The touchscreen is fairly responsive, though it’s e-ink and there are limits to refresh rates. The physical buttons to turn the page are perfect, and I still can’t believe Amazon took them off their Kindles (though I guess I understand them removing the keyboard… even though I liked it).

I actually like mine so much, I bought a second of the same model after I somehow managed to lose my first one. So the one thing I wish they had was integration with Apple Airtag or one of the other device tracking networks!

speck,

Can you do things like highlight text on a kobo? And can you then export with all the edits?

Also, can you the plug into a computer and transfer books over?

DesertCreosote,

You can definitely highlight text. I haven’t tried exporting with edits, though, so I can’t speak to that.

You can plug it in and transfer, but again, I haven’t personally done it. I get most of my books from the library, so I just use the Overdrive stuff for that.

speck,

I should follow the law of the internet and insist that you can't export edits and that's why Kobo sux and then someone can let us know if it can!

In all seriousness, I appreciate the input, thank you! I just don't enjoy reading on my ipad as much as I did on the Nook I had, back when. So the recent posts about e-readers has me considering getting one. But I also need the ability to highlight and jot notes when I read.

Chetzemoka, (edited ) in [EXPERIMENTAL] What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase [**Bolded Substance Name (Brand/Street Name)** + New Paragraph folks]

Apigenin (herbal supplement)

Insomnia, anxiety

Derived from chamomile flowers (and other plant sources), I’ve found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I’ve tried them all.)

cheese_greater,

Was curious about this since Andrew Huberman mentioned it

Chetzemoka,

It’s really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you’ll see advertised. I only mention because I think the standard advertised range is probably too low for people like me.

cheese_greater, (edited )

Thanks! Is it expensive? How much do you get?

Chetzemoka,

Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha

I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.

cheese_greater,

Is that the dose, 1/night before bed?

Chetzemoka,

Yep, that’s the usual recommended dose - 200mg like an hour before bedtime

cheese_greater,

Would you recommend it for other seniors particularly? My grandmother might like something like this? She liked Calm Magnesium Sleep except for the GI effect of magnesium citrate and I wonder it this might be easier on the system to the extent she’d be into it

Chetzemoka,

I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn’t interact with the most common blood pressure or cardiac meds that older folks often take.

I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.

The only two caveats I would add are: she should definitely tell her doctors she’s taking it, as with any OTC supplement. And if she’s specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don’t use it as much anymore, but it’s not unheard of.)

Hope that helps! (I’m a cardiac nurse. I work with older folks a lot.)

cheese_greater, (edited )

Thanks, I’m in talks with the right expert hehe :)

More specifically, is it genuinely helpful for quality of sleep, all other things being constructive towards that end in turn?

Chetzemoka,

Hahaha, I love working with older folks. They’re my favorite patients.

cheese_greater, (edited )

Re:Apigenin -> sleep quality?

Chetzemoka,

Literally the only thing that gives me refreshing sleep. (See also: mitochondrial dysfunction that I mentioned in my other comment about CQ10.) Apigenin seems to improve what’s called “sleep architecture” in a way that none of the pharmaceuticals I’ve ever tried do.

cheese_greater,

Shit, I may have to try it first. Im getting other sleep stuff done but every bit helps

Chetzemoka,

Here, I found a good article for you:

uspharmacist.com/…/assisting-seniors-with-insomni…

cheese_greater,

I gotta sleep soon aha but I’ll leave you with a last question for tonight: what do you think mediates Apigenin’s efficacy for sleep? Like what is the mechanism behind its efficacy, what systems does it modulate?

Thanks and no rush, I’ll listen to that article tomorrow :)

Chetzemoka,

So, it’s interesting, because it’s well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn’t respond consistently to the drug we use to reverse benzos (called flumazenil).

So… we’re not entirely sure? It could still be the GABA effects that help with sleep. But there’s also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer’s, for example.

Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:

www.ncbi.nlm.nih.gov/pmc/articles/PMC6472148/

cheese_greater, (edited )

Thanks and I will check those out. Does the flumazenil displace GABA_B ligands/receptors as well or only _A?

Thats all for tonight, night

Chetzemoka,

Oh you’re getting in the weeds now hahaha. Looks like it’s primarily GABA_A

www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/

I just had to look that shit up haha. I’ve never thought to check into it beyond just “you’re not breathing, so I’m about to make you very angry by reversing your high, sorry bro” lol

cheese_greater,

It seems as if _B ligands are both way less ubiquitous and also variably less-reinforcing than traditional alcohol-type sedatives like benzos/barbs/sleeps, although I say that very conjecturally (is that a word? Aha). And less likely to be overdone to the point the therapeutic window is being dangerously exceeded or a polypharmacy situation that leads to medical emergency like that

From my own experience with baclofen which I used to wean off drinking and help with the induced anxiety, I didn’t really find it super pleasent or enjoyable and there were enough annoying sides like tearing up and a crappy fuzziness that was super offputting. Alcohol and sedatives (especially sleeping pills), totes different story (I find them as a class GABA_A way more dangerous and mindlessly compulsive.

Chetzemoka,

Huh, now that’s super interesting.

Ok you and I both have to go to sleep, but now you’ve got me wondering about the eternal debate amongst our medical residents about benzos vs. barbiturates for acute alcohol withdrawal. I’ll have to read up on this some more

cheese_greater,

Yeah, ask about baclofen, its famously advocated by a French dr who struggled to find a proper treatment for his alcoholism until he arrived on baclofen. End of My Addiction is the title.

I used it as an adjuvant treatment along with naltrexone and careful timing in terms of the actual drinking that was required to make the naltrexone effective in addressing the neurochemical basis for much of the compulsion from alcohol.

Drusas, in What are the best e-readers on the market?

I know everybody hates Amazon and they want an alternative to the Kindle, but my Kindle is waterproof and I almost exclusively want to use it in the bathtub. I also want one that doesn't have a strong backlight and feels natural to look at. The Kindle is damn near perfect.

Grass,

I’ve taken my Kobo into a stream that people cliff jump into. I felt off about it because it doesn’t look waterproof even though it is advertised as such. Maybe I’m just too old for waterproof electronics.

Drusas,

That's fair. I mostly want my device to survive if my dog knocks it into the bathtub. This has happened before and it will happen again.

  • All
  • Subscribed
  • Moderated
  • Favorites
  • asklemmy@lemmy.world
  • localhost
  • All magazines
  • Loading…
    Loading the web debug toolbar…
    Attempt #