That was a great watch. I love how the next step in competitive Tetris means the player will need to learn which moves won’t crash it so you can get to the final level. How cool.
I think that there is a massive gap between competitive sports (almost inherently toxic) and massively online games (juvenile masses combined with lack of moderation) and, for example, speed running and challenge games or tabletop and board gaming which are all likely to be more wholesome and positive even if there is a competitive angle.
There is probably more visibility on the first side. Maybe because that’s where the money is. And I very much agree that this was a nice story and I hope there will be more of this kind of inspiration shown in public.
Kind of reminds me of Pleasant Green who scambaits, but also makes attempts to get to know the scammers and actually makes an effort to help them turn their lives around.
How in did violent crimes decrease in the US? Didn’t Mr. housespeaker get his head smashed in this year? If nbc news is saying the crime rate dropped, that’s a bad sign. If anyone has a reason we should trust mainstream, please state your case.
I find it hard to believe that during a year of homelessness, armed robberies and drug abuse that this year would have seen less violent crime. The year ended with pro-palestinians calling for a massacre!
I like how he pulls out “If nbc news is saying…” and the posted link goes right to Time.com, not even taking into account the data source which is listed right under the graph in that section of the article. Arguing with these MAGA people is useless because they’re not even doing any basic research, they’re just knee-jerk reacting to whatever liberal source they think it comes from. They spread fecal matter from their mouths and their fingertips everytime they talk or write and somehow it becomes everybody else’s responsibility to clean up their shit arguments.
I would want to add: A lot of scientific studies are made to understand animals better - their well-being, their language, their relation with us. Another series of studies has begun to document human knowledge around plants and their traditional use.
Myself and many humans around me have started to seek contact and communication with our non-human neighbors. Even people who still say “It’s all lost, I don’t care” show clear signs of caring.
It’s great to see a major publication is pushing great news for the world. There’s a lot of noise out there about every single negative thing, but the overall trend is positive, even if we don’t see it.
The VAST majority of people are just out there trying to live their lives and make the world a little better every day, and it’s great to see that their efforts are moving the needle.
zosurabalpin doesn’t seem to work on any other Gram-negative bacteria besides A. baumannii. The proteins in the LPS transporter complex are not conserved across different bacteria. Thus, targeting the LPS transporters of other nefarious Gram-negative bacteria will take yet more drug development research. One bright side of this, as Gugger and Hergenrother note in their commentary, is that it may produce species-specific antibiotics, which could protect patients’ microbiomes from being obliterated by broad-spectrum drugs, which we now appreciate is bad for human health.
And, of course, with any new antibiotic, there’s the inevitability that bacteria will develop resistance. The researchers already found that select mutations in the LPS transporter machinery can knock back the drug’s potency. Also, A. baumannii doesn’t need LPS to stay alive. That said, simply blocking LPS production would leave A. baumannii more vulnerable, and it’s unclear how that trade-off will play out in clinical settings.
No, not really. It’s only a matter of time before they are resistant to this one too, and I don’t know that we can help it even if distribution antibiotics carefully.
A war like Ukraine or a Genocide like Gaza tends to speed up bacterial resistance a lot, while breakthroughs are rare. I don’t see anything in this article that says it will be more difficult for bugs to become resistant to it. All bugs evolve constantly.
Name me one thing humans have been 100% reponsible with, from nuclear weapons to airplanes. Especially when it comes to antibiotics, people are going to take what they have available.
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